Results 91 to 100 of about 7,937 (163)

Peer review of the pesticide risk assessment of the active substance Trichoderma afroharzianum (formerly harzianum) T‐22

EFSA Journal, Volume 24, Issue 10, October 2026.
Abstract The conclusions of the European Food Safety Authority (EFSA) following the peer review of the initial risk assessments carried out by the competent authorities of the rapporteur Member State, Sweden, and co‐rapporteur Member State, Netherlands, for the pesticide active substance Trichoderma afroharzianum (formerly harzianum) T‐22 are reported.
European Food Safety Authority (EFSA), Fernando Álvarez, Maria Arena, Domenica Auteri, Sofia Batista Leite, Marco Binaglia, Anna Federica Castoldi, Arianna Chiusolo, Angelo Colagiorgi, Mathilde Colas, Federica Crivellente, Chloe De Lentdecker, Isabella De Magistris, Gabriella Fait, Franco Ferilli, German Giner Santonja, Varvara Gouliarmou, Alessio Ippolito, Frederique Istace, Dimitra Kardassi, Aude Kienzler, Anna Lanzoni, Roberto Lava, Renata Leuschner, Alberto Linguadoca, Mariano Lopez Romano, Jochem Louisse, Christopher Lythgo, Oriol Magrans, Iris Mangas, Silvia Mazzega, Andrea Mioč, Ileana Miron, Tunde Molnar, Laura Padovani, Vincenzo Padricello, Martina Panzarea, Juan Manuel Parra Morte, Simone Rizzuto, Miguel Santos, Rositsa Serafimova, Rachel Sharp, Csaba Szentes, Anne Theobald, Manuela Tiramani, Giorgia Vianello, Laura Villamar‐Bouza, Adriana Scattareggia Marchese   +47 more
wiley   +1 more source

Modification of the existing maximum residue levels for propyzamide in oilseeds and honey

EFSA Journal, Volume 24, Issue 10, October 2026.
Abstract In accordance with Article 6 of Regulation (EC) No 396/2005, the applicant Corteva submitted a request to the competent national authority in Sweden to modify the existing maximum residue levels (MRLs) for the active substance propyzamide in oilseed rape, mustard seeds, gold of pleasure seeds, linseeds, sesame seeds, hemp seeds, borage seeds ...
European Food Safety Authority (EFSA), Sofia Batista Leite, Giulia Bellisai, Giovanni Bernasconi, Marco Binaglia, Irene Castellan, Anna Federica Castoldi, Arianna Chiusolo, Mathilde Colas, Federica Crivellente, Monica Del Aguila, Lucien Ferreira, Frederique Istace, Anna Lanzoni, Renata Leuschner, Jochem Louisse, Iris Mangas, Silvia Mazzega, Andrea Mioč, Martina Panzarea, Juan Manuel Parra Morte, Simone Rizzuto, Marta Szot, Manuela Tiramani, Alessia Verani   +24 more
wiley   +1 more source

Safety evaluation of the food enzyme containing endo‐polygalacturonase, pectinesterase, pectin lyase and arabinan endo‐1,5‐α‐l‐arabinanase activities from the non‐genetically modified Aspergillus sp. strain ASNSC

EFSA Journal, Volume 24, Issue 10, October 2026.
Abstract The food enzyme containing endo‐polygalacturonase (1,4‐α‐d‐galacturonan glycanohydrolase; EC 3.2.1.15), pectinesterase (pectin pectylhydrolase; EC 3.1.1.11), pectin lyase (1,4‐6‐O‐methyl‐α‐d‐galacturonan lyase; EC 4.2.2.10) and arabinan endo‐1,5‐α‐l‐arabinanase (5‐α‐l‐arabinan 5‐α‐l‐arabinanohydrolase; EC 3.2.1.99) activities is produced with ...
EFSA Panel on Food Enzymes (FEZ), Holger Zorn, José Manuel Barat Baviera, Claudia Bolognesi, Francesco Catania, Gabriele Gadermaier, Ralf Greiner, Baltasar Mayo, Alicja Mortensen, Yrjö Henrik Roos, Marize L. M. Solano, Henk Van Loveren, Laurence Vernis, Cristina Andreoli, Andrea Terron, Andrey Yurkov, Magdalena Andryszkiewicz, Daniele Cavanna, Ana Criado, Simone Lunardi, Yi Liu   +20 more
wiley   +1 more source

Safety evaluation of an extension of use of the food enzyme non‐reducing end α‐l‐arabinofuranosidase from the genetically modified Trichoderma reesei strain NZYM‐GV [PDF]

EFSA J
Abstract The food enzyme non‐reducing end α‐l‐arabinofuranosidase (α‐l‐arabinofuranoside non‐reducing end α‐l‐arabinofuranosidase; EC 3.2.1.55) is produced with the genetically modified Trichoderma reesei strain NZYM‐GV by Novozymes A/S. The safety of this food enzyme was evaluated previously, and it did not give rise to safety concerns when used in ...
EFSA Panel on Food Enzymes (FEZ), Holger Zorn, José Manuel Barat Baviera, Claudia Bolognesi, Francesco Catania, Gabriele Gadermaier, Ralf Greiner, Baltasar Mayo, Alicja Mortensen, Yrjö Henrik Roos, Marize L. M. Solano, Henk Van Loveren, Laurence Vernis, Daniele Cavanna, Yi Liu, Valentina Tokić   +15 more
europepmc   +2 more sources

Safety evaluation of the food enzyme cellulase from the genetically modified Trichoderma reesei strain NZYM‐FS

EFSA Journal, Volume 24, Issue 10, October 2026.
Abstract The food enzyme cellulase (4‐(1,3; 1,4)‐β‐d‐glucan‐4‐glucanohydrolase, EC 3.2.1.4) is produced with the genetically modified Trichoderma reesei strain NZYM‐FS by Novozymes A/S. The genetic modifications did not give rise to safety concerns. The food enzyme was considered free from viable cells of the production organism and its DNA.
EFSA Panel on Food Enzymes (FEZ), Holger Zorn, José Manuel Barat Baviera, Claudia Bolognesi, Francesco Catania, Gabriele Gadermaier, Ralf Greiner, Baltasar Mayo, Alicja Mortensen, Yrjö Henrik Roos, Marize L. M. Solano, Henk Van Loveren, Laurence Vernis, Cristina Andreoli, Andrea Terron, Andrey Yurkov, Ana Gomes, Daniele Cavanna, Cristina Fernández‐Fraguas, Natália Kovalkovičová, Yi Liu   +20 more
wiley   +1 more source

Safety evaluation of a food enzyme containing leucyl aminopeptidase and Xaa‐Pro dipeptidyl‐peptidase activities from the non‐genetically modified Aspergillus sp. strain DAP 19‐109

EFSA Journal, Volume 24, Issue 10, October 2026.
Abstract The food enzyme containing leucyl aminopeptidase (EC 3.4.11.1) and Xaa‐Pro dipeptidyl‐peptidase (EC 3.4.14.11) activities is produced with the non‐genetically modified Aspergillus sp. strain DAP 19‐109 by Shin Nihon Chemical Co., Ltd. The food enzyme was considered free from viable cells of the production organism. It is intended to be used in
EFSA Panel on Food Enzymes (FEZ), Holger Zorn, José Manuel Barat Baviera, Claudia Bolognesi, Francesco Catania, Gabriele Gadermaier, Ralf Greiner, Baltasar Mayo, Alicja Mortensen, Yrjö Henrik Roos, Marize L. M. Solano, Henk Van Loveren, Laurence Vernis, Cristina Andreoli, Andrea Terron, Andrey Yurkov, Simone Lunardi, Magdalena Andryszkiewicz, Daniele Cavanna, Natalia Kovalkovicova, Yi Liu   +20 more
wiley   +1 more source

Safety assessment of (S)-Equol: Subchronic toxicity study in Sprague Dawley Rats

Toxicology Reports
(S)-Equol is a chemically synthesized nutraceutical compound and its consumption provides several health benefits for humans. The new nutraceutical, enantiopure (S)-Equol was studied for acute and sub-chronic toxicity in Sprague Dawley Rats.
Seethakallu Ramachandraiah AnandaKumar, Mukund Handral, Srinivas Seekallu   +2 more
doaj   +1 more source

Nonmonotonic Dose–Response Curves Occur in Dose Ranges That Are Relevant to Regulatory Decision-Making

Dose-Response, 2018
Non-monotonic dose response curves (NMDRCs) occur in cells, tissues, animals and human populations in response to nutrients, vitamins, pharmacological compounds, hormones and endocrine disrupting chemicals (EDCs).
Corinne E. Hill, J. P. Myers, Laura N. Vandenberg   +2 more
doaj   +1 more source

Safety evaluation of the food enzyme phospholipase A1 from the non‐genetically modified Fusarium commune strain LFC

EFSA Journal, Volume 24, Issue 10, October 2026.
Abstract The food enzyme phospholipase A1 (phosphatidylcholine 1‐acylhydrolase; EC 3.1.1.32) is produced with the non‐genetically modified Fusarium commune strain LFC by DSM Food Specialties B.V. The food enzyme was considered free from viable cells of the production organism. It is intended to be used in two food manufacturing processes.
EFSA Panel on Food Enzymes (FEZ), Holger Zorn, José Manuel Barat Baviera, Claudia Bolognesi, Francesco Catania, Gabriele Gadermaier, Ralf Greiner, Baltasar Mayo, Alicja Mortensen, Yrjö Henrik Roos, Marize L. M. Solano, Henk Van Loveren, Laurence Vernis, Cristina Andreoli, Andrea Terron, Andrey Yurkov, Simone Lunardi, Magdalena Andryszkiewicz, Ana Criado, Yi Liu, Irene Bonino   +20 more
wiley   +1 more source

The estimation and translation uncertainties in applying NOAEL to clinical dose escalation

Clinical and Translational Science
The systemic exposure at the no‐observed‐adverse‐effect‐level (NOAEL) estimated from animals is an important criterion commonly applied to guard the safety of participants in clinical trials of investigational drugs.
Chao Chen, Silvia Maria Lavezzi, David McDougall   +2 more
doaj   +1 more source