Results 91 to 100 of about 1,583,705 (314)

Analyzing body composition in living kidney donors: impact on post-transplant kidney function

Frontiers in Nephrology
Living donor kidney transplantation boasts superior patient and graft survival rates compared to deceased donor kidney transplantation. However, the impact of living donor body composition (BC) on post-transplant kidney function remains uncertain.
Evelien E. Quint, Lisa B. Westenberg, Gertrude J. Nieuwenhuijs-Moeke, Eva A. N. van den Broek, Marcel Zorgdrager, Alain R. Viddeleer, Stephan J. L. Bakker, Ija M. Nolte, Marco van Londen, Robert A. Pol, TransplantLines Investigators   +10 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Sacrificial electron donor reagents for solar fuel production

, 2017
Although justly considered as a cumbersome component in artificial photosystems, these simple molecules are a “necessary evil” to drive photo-induced reactions aiming at producing high added value molecules by photo-induced reduction of low energy value ...
Y. Pellegrin, F. Odobel
semanticscholar   +1 more source

Enhanced CRISPR/Cas9-mediated precise genome editing by improved design and delivery of gRNA, Cas9 nuclease, and donor DNA.

Journal of Biotechnology, 2017
While CRISPR-based gene knock out in mammalian cells has proven to be very efficient, precise insertion of genetic elements via the cellular homology directed repair (HDR) pathway remains a rate-limiting step to seamless genome editing.
Xiquan Liang, J. Potter, Shantanu Kumar, N. Ravinder, J. Chesnut   +4 more
semanticscholar   +1 more source

Retraction Note: miR-1301 inhibits hepatocellular carcinoma cell migration, invasion, and angiogenesis by decreasing Wnt/β-catenin signaling through targeting BCL9

Cell Death and Disease, 2023
Chao Yang, Yonghua Xu, Feng Cheng, Yuanchang Hu, Shikun Yang, Jianhua Rao, Xuehao Wang   +6 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Chimerism in Myeloid Malignancies following Stem Cell Transplantation Using FluBu4 with and without Busulfan Pharmacokinetics versus BuCy

Advances in Hematology, 2017
In the era of precision medicine, the impact of personalized dosing of busulfan is not clear. We undertook a retrospective analysis of 78 patients with myeloid malignancies who received fludarabine and busulfan (FluBu4) with or without measuring Bu ...
Shatha Farhan, Michael Bazydlo, Klodiana Neme, Nancy Mikulandric, Edward Peres, Nalini Janakiraman   +5 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Effects of Donor Oocytes and Cells Treated with Porcine Follicular Fluid-drived Exosome on SCNT embryo Development

Journal of the Korea Academia-Industrial cooperation Society
This study analyzed the effects of exosomes extracted from porcine follicular fluid (pFF) on porcine somatic cell nuclear transfer (SCNT). Exosomes were extracted using either ultracentrifugation alone or ultracentrifugation, followed by size exclusion ...
Jingu No, Taeuk Kwak, Seokho Kim, Haesun Lee, Poongyeon Lee, K. Oh, Seunghoon Lee   +6 more
semanticscholar   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source