Results 1 to 10 of about 128,038 (170)

Immune checkpoint inhibitors plus capecitabine and oxaliplatin in unresectable or advanced biliary tract cancer patients: A retrospective study

Frontiers in Oncology, 2022
ObjectiveImmune checkpoint inhibitors (ICIs) have recently been increasingly used in cancer treatment, whereas their clinical application in biliary tract cancer (BTC) patients is uncommon.
Jie Zhao, Yongzhong Guo, Wenzhou Ding, Guoyong Han, Chuanwei Jiang, Chao Yang, Yuanchang Hu, Long Zhang, Chen Wu, Ming Ni, Xiangyi Kong, Tian Huang, Chuanyong Zhang, Yongxiang Xia   +13 more
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GLIS1 intervention enhances anti-PD1 therapy for hepatocellular carcinoma by targeting SGK1-STAT3-PD1 pathway

Journal for ImmunoTherapy of Cancer, 2023
Background GLI-similar 1 (GLIS1) is one of of Krüppel-like zinc finger proteins, which are either stimulators or inhibitors of genetic transcription. Nevertheless, its effects on T cell were elusive.Methods In this study, we intend to explore the effects
Li Liu, Guoqiang Sun, Yongxiang Xia, Xuehao Wang, Hanyuan Liu, Tian Huang, Ziyi Chen, Weiwei Tang, Guangshun Sun, Hengsong Cao, Dawei Rong, Yuliang Wang, Xiaopei Hao, Zhiying Zheng, Junwei Kang   +14 more
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The Living Donor Collective: A Scientific Registry for Living Donors [PDF]

American Journal of Transplantation, 2017
In the setting of an overall decline in living organ donation and new questions about long-term safety, a better understanding of outcomes after living donation has become imperative. Adequate information on outcomes important to donors may take many years to ascertain and may be evident only by comparing large numbers of donors with suitable controls.
Kasiske, BL, Asrani, SK, Dew, MA, Henderson, ML, Henrich, C, Humar, A, Israni, AK, Lentine, KL, Matas, AJ, Newell, KA, Rudow, D LaPointe, Massie, AB, Snyder, JJ, Taler, SJ, Trotter, JF, Waterman, AD, participants, on behalf of the Living Donor Collective   +16 more
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Development and external validation of a nomogram for predicting the effect of tumor size on survival of patients with perihilar cholangiocarcinoma

BMC Cancer, 2020
Background The effect of tumor size on account of long-term survival results in perihilar cholangiocarcinoma (PCCA) patients has remained a controversial debate.
Yaodong Zhang, Zhengshan Wu, Xing Wang, Changxian Li, Jiang Chang, Wangjie Jiang, Hongwei Wang, Yirui Wang, Xiangcheng Li   +8 more
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m6A modification of circHPS5 and hepatocellular carcinoma progression through HMGA2 expression

Molecular Therapy: Nucleic Acids, 2021
N6-methyladenosine (m6A) is capable of mediating circRNA generation in carcinoma biology. Nevertheless, the posttranscriptional systems of m6A and circRNA in hepatocellular carcinoma (HCC) development are still unclear.
Dawei Rong, Fan Wu, Chen Lu, Guangshun Sun, Xiaoli Shi, Xiaoyuan Chen, Yongjiu Dai, Weizhe Zhong, Xiaopei Hao, Jinren Zhou, Yongxiang Xia, Weiwei Tang, Xuehao Wang   +12 more
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CircPAK1 promotes the progression of hepatocellular carcinoma via modulation of YAP nucleus localization by interacting with 14-3-3ζ

Journal of Experimental & Clinical Cancer Research, 2022
Background Circular RNA (circRNA), a new class of non-coding RNA, has obvious correlations with the occurrence and development of many diseases, including tumors. This study aimed to investigate the potential roles of circPAK1 in hepatocellular carcinoma
Xiaopei Hao, Yao Zhang, Xiaoli Shi, Hanyuan Liu, Zhiying Zheng, Guoyong Han, Dawei Rong, Chuanyong Zhang, Weiwei Tang, Xuehao Wang   +9 more
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Living donor nephrectomy [PDF]

Revista da Associação Médica Brasileira, 2018
The Guidelines Project, an initiative of the Brazilian Medical Association, aims to combine information from the medical field in order to standardize producers to assist the reasoning and decision-making of doctors.The information provided through this project must be assessed and criticized by the physician responsible for the conduct that will be ...
Antonio Silvinato, Wanderley M. Bernardo, Luis Sérgio Santos   +2 more
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Targeting Immune Cells in the Tumor Microenvironment of HCC: New Opportunities and Challenges

Frontiers in Cell and Developmental Biology, 2021
Immune associated cells in the microenvironment have a significant impact on the development and progression of hepatocellular carcinoma (HCC) and have received more and more attention.
Xiaopei Hao, Guangshun Sun, Yao Zhang, Xiangyi Kong, Dawei Rong, Jinhua Song, Weiwei Tang, Xuehao Wang   +7 more
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Single-cell RNA-sequencing atlas reveals an FABP1-dependent immunosuppressive environment in hepatocellular carcinoma

Journal for ImmunoTherapy of Cancer, 2023
Background Single-cell RNA sequencing, also known as scRNA-seq, is a method profiling cell populations on an individual cell basis. It is particularly useful for more deeply understanding cell behavior in a complicated tumor microenvironment.
Li Liu, Tingting Feng, Qian Zhang, Chuan Liu, Yongxiang Xia, Xuehao Wang, Hanyuan Liu, Tian Huang, Xiaoyi Zhang, Weiwei Tang, Guangshun Sun, Hengsong Cao, Gu-Wei Ji, Wenhao Wu   +13 more
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CHSY1 promotes CD8+ T cell exhaustion through activation of succinate metabolism pathway leading to colorectal cancer liver metastasis based on CRISPR/Cas9 screening

Journal of Experimental & Clinical Cancer Research, 2023
Background The most common site of metastasis in colorectal cancer (CRC) is the liver and liver metastases occur in more than 50% of patients during diagnosis or treatment.
Guangshun Sun, Siqi Zhao, Zhongguo Fan, Yuliang Wang, Hanyuan Liu, Hengsong Cao, Guoqiang Sun, Tian Huang, Hongzhou Cai, Hong Pan, Dawei Rong, Yun Gao, Weiwei Tang   +12 more
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