Results 31 to 40 of about 142,808 (310)

Paired and altruistic kidney donation in the UK: algorithms and experimentation [PDF]

, 2012
We study the computational problem of identifying optimal sets of kidney exchanges in the UK. We show how to expand an integer programming-based formulation [1, 19] in order to model the criteria that constitute the UK definition of optimality.
David F. Manlove, O’Malley, G., Gregg O’Malley, Manlove, D.F.   +3 more
core   +1 more source

Deceased donor-initiated chains (DEC-K): efficacy and outcomes at 4 year of a pioneering program [PDF]

, 2022
openIl trapianto di rene è attualmente il miglior trattamento per i pazienti in insufficienza renale cronica terminale. Tra le due modalità di trapianto esistenti, da donatore deceduto e da donatore vivente, quest’ultima rappresenta la risorsa da ...
MALAGUTI, ALICE
core  

Defective efferocytosis by aged macrophages promotes STING signaling mediated inflammatory liver injury

Cell Death Discovery, 2023
Aged livers have shown aggravated liver ischemia and reperfusion (IR) injury. Timely efferocytosis of apoptotic cells is a key mechanism for avoiding excessive inflammation and tissue injury.
Haoran Hu, Xuyu Cheng, Fei Li, Zhu Guan, Jian Xu, Dongming Wu, Yiyun Gao, Xinyu Zhan, Ping Wang, Haoming Zhou, Zhuqing Rao, Feng Cheng   +11 more
doaj   +1 more source

Inhibition of APOC1 promotes the transformation of M2 into M1 macrophages via the ferroptosis pathway and enhances anti-PD1 immunotherapy in hepatocellular carcinoma based on single-cell RNA sequencing

Redox Biology, 2022
Single-cell RNA-sequencing (scRNA-seq) presents better insights into cell behavior in the context of a complex tumor microenvironment by profiling single-cell populations.
Xiaopei Hao, Zhiying Zheng, Hanyuan Liu, Yao Zhang, Junwei Kang, Xiangyi Kong, Dawei Rong, Guangshun Sun, Guoqiang Sun, Li Liu, Haibo Yu, Weiwei Tang, Xuehao Wang   +12 more
doaj   +1 more source

Living Kidney Donor Knowledge of Provided Information and Informed Consent: The PRINCE Study† [PDF]

, 2022
BACKGROUND: Informed consent for living kidney donation is paramount, as donors are healthy individuals undergoing surgery for the benefit of others. The informed consent process for living kidney donors is heterogenous, and the question concerns how ...
on behalf of the Dutch Working Group Informed Consent for Live Donor Nephrectomy (“PRINCE”)
core  

Nogo-B is a key mediator of hepatic ischemia and reperfusion injury

Redox Biology, 2020
Nogo-B is an endoplasmic reticulum-residential protein with distinctive functions in different diseases. However, it remains unclear the role of Nogo-B in liver sterile inflammatory injury.
Jianhua Rao, Feng Cheng, Haoming Zhou, Wenjie Yang, Jiannan Qiu, Chao Yang, Xuehao Ni, Shikun Yang, Yongxiang Xia, Xiongxiong Pan, Feng Zhang, Ling Lu, Xuehao Wang   +12 more
doaj   +1 more source

Carcinomas and Carcinoid Tumors of the Lungs and Bronchi in Children and Adolescents: The EXPeRT Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Primary lung carcinomas and bronchial carcinoid tumors (BC) are very rare malignancies in childhood. While typical BC and mucoepidermoid carcinomas are mostly low‐grade, localized tumors with a more favorable prognosis than in adults, necessitating avoidance of overtreatment, adenocarcinomas of the lung are often diagnosed at advanced disease ...
Michael Abele, Calogero Virgone, Michaela Kuhlen, Sabine Irtan, Yves Reguerre, Malgorzata Krawczyk, Ewa Bien, Tal Ben‐Ami, Maja Cesen, Ricardo Lopez‐Almaraz, Andrea Ferrari, Gianni Bisogno, Dominik T. Schneider, Abbas Agaimy, Constantin Lapa, Hubert Ducou le Pointe, Rainer Claus, Catherine Daniel, Ines B. Brecht, Daniel Orbach   +19 more
wiley   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Living-Donor Kidney Transplantation [PDF]

Journal of the American Society of Nephrology, 2005
The first successful living-donor kidney transplant was performed 50 yr ago. Since then, in a relatively brief period of medical history, living kidney transplantation has become the preferred treatment for those with ESRD. Organ replacement from either a live or a deceased donor is preferable to dialysis therapy because transplantation provides a ...
Connie L, Davis, Francis L, Delmonico
openaire   +2 more sources

Evolution of living donor liver transplantation over 10 years: experience of a single center. [PDF]

, 2008
PURPOSE: To evaluate the changes in living donor liver transplantations (LDLTs) over the last 10 years, we analyzed our experience of performing LDLT in a single center.
Takatsuki, Mitsuhisa, Hidaka, Masaaki, Tajima, Yoshitsugu, Kanematsu, Takashi, Eguchi, Susumu   +4 more
core   +1 more source