Results 101 to 110 of about 1,583,705 (314)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Frontiers in Cardiovascular MedicineBackgroundThe impact of transcatheter closure of coronary artery fistula (CAF) and residual shunt after occlusion on improving blood flow in the donor vessel remains uncertain.ObjectivesTo evaluate the functional impact on the donor vessel following CAFs
Zhenchi Sang +5 more
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Donor complications and donor care [PDF]
ISBT Science Series, 2009 Vasovagal reaction (VVR) is the most common adverse reaction associated with blood donation, and we have analysed risk factors and suggested preventive measures for VVR.Donor complications In Japan, there were 5 137 612 donations in 2008, and the incidence of all donor complications was 1·16% (male 0·87%, female 1·76%).
openaire +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Causal Effect of Donor Source on Survival of Renal Transplantation Using Marginal Structural Models
Iranian Journal of Public Health, 2018 Background: Marginal Structural Models (MSMs) are novel methods to estimate causal effect in epidemiology by using Inverse Probability of Treatment Weighting (IPTW) and Stabilized Weight to reduce confounding effects.
Amir ALMASI-HASHIANI +3 more
doaj
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Thigh-based Breast Reconstruction: A Decade of Experience With the Diagonal Upper Gracilis Flap
Plastic and Reconstructive Surgery, Global OpenBackground:. The thigh is an alternative donor site for autologous breast reconstruction when abdominal flaps are unsuitable, though limited tissue and donor-site complications pose challenges.
Oriana Haran, MD +3 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source