Results 221 to 230 of about 914,178 (235)
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Experimental Pathology, 1989
Four methods for intra- and inter-species dose extrapolation for inhalation reference doses are discussed. Dichloromethane is used as an example to illustrate quantitative differences in the methods. The methods include a procedure recommended by the U.S.
J H, Overton, A M, Jarabek
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Four methods for intra- and inter-species dose extrapolation for inhalation reference doses are discussed. Dichloromethane is used as an example to illustrate quantitative differences in the methods. The methods include a procedure recommended by the U.S.
J H, Overton, A M, Jarabek
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A new approach to deriving community exposure guidelines from “no-observed-adverse-effect levels”
Regulatory Toxicology and Pharmacology, 1990The world community desires accurate and reliable information about possible health hazards from exposure to chemicals in the environment. For example, Title III of the Superfund Amendments and Reauthorization Act (SARA, U.S. Congress, 1986) requires plant operators to disclose data on air, water, and waste emissions for over 300 chemicals.
S C, Lewis, J R, Lynch, A I, Nikiforov
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Critical Reviews in Toxicology, 2016
Although consumption of chrysotile asbestos has decreased since the 1970s, the latency period of asbestos-related cancers is thought to be at least 20-30 years, and therefore the potential health risks associated with historical exposures is still actively researched.
Jennifer S, Pierce +2 more
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Although consumption of chrysotile asbestos has decreased since the 1970s, the latency period of asbestos-related cancers is thought to be at least 20-30 years, and therefore the potential health risks associated with historical exposures is still actively researched.
Jennifer S, Pierce +2 more
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Journal of Allergy and Clinical Immunology, 2006
Current labeling practices for allergenic foods like peanut can be inadequate. For future regulatory and industry guidelines, information on no-observed-adverse-effect levels (NOAELs) and eliciting doses (EDs) for allergenic foods is necessary.To determine NOAEL and ED in a representative group of peanut-sensitized children, relate these data to ...
Annebeth E, Flinterman +8 more
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Current labeling practices for allergenic foods like peanut can be inadequate. For future regulatory and industry guidelines, information on no-observed-adverse-effect levels (NOAELs) and eliciting doses (EDs) for allergenic foods is necessary.To determine NOAEL and ED in a representative group of peanut-sensitized children, relate these data to ...
Annebeth E, Flinterman +8 more
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Zhongguo yi liao qi xie za zhi = Chinese journal of medical instrumentation, 2020
The purpose of this study was to investigate the NOAEL of the nickel ion and provide with basic data for the biological evaluation of those medical devices containing nickel. Five groups SD rats were repeatedly exposed during 14 d respectively to nickel at first stage doses of 4.9, 3.7, 2.5 mg/(kg.d), and the second stage doses of 1.2, 0.25 mg/(kg.d ...
Xueying, He +9 more
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The purpose of this study was to investigate the NOAEL of the nickel ion and provide with basic data for the biological evaluation of those medical devices containing nickel. Five groups SD rats were repeatedly exposed during 14 d respectively to nickel at first stage doses of 4.9, 3.7, 2.5 mg/(kg.d), and the second stage doses of 1.2, 0.25 mg/(kg.d ...
Xueying, He +9 more
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Nigerian Journal of Animal Production
There is the need to determine the no observed adverse effect level and no observed effect level (NOAEL and NOEL) of fipronil using haematological indices and liver markers of albino rats as recent trend in development of resistance by pests may lead to increasing the quantity of fipronil required to control them. Acute toxicity of fipronil (Terminator"
V. U. OMOJA +4 more
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There is the need to determine the no observed adverse effect level and no observed effect level (NOAEL and NOEL) of fipronil using haematological indices and liver markers of albino rats as recent trend in development of resistance by pests may lead to increasing the quantity of fipronil required to control them. Acute toxicity of fipronil (Terminator"
V. U. OMOJA +4 more
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2000
The purpose of the present study was to establish for both saline-pretreated and pyridostigmine-pretreated conscious guinea pigs whole-body exposed to low levels of GB vapor: (i) The Lowest Observable Effect Level (LOEL) for GB, i.e., the C.t-value (t = 5-h) of exposure at which an internal dose (fluoride-regenerated GB from blood ChE) becomes ...
Trap, H.C. +8 more
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The purpose of the present study was to establish for both saline-pretreated and pyridostigmine-pretreated conscious guinea pigs whole-body exposed to low levels of GB vapor: (i) The Lowest Observable Effect Level (LOEL) for GB, i.e., the C.t-value (t = 5-h) of exposure at which an internal dose (fluoride-regenerated GB from blood ChE) becomes ...
Trap, H.C. +8 more
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Determining the No-Observed-Adverse-Effect Level in Continuous Response
1993Yasuki Kikuchi +2 more
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Statistical uncertainty in the no-observed-adverse-effect level*1
Fundamental and Applied Toxicology, 1989openaire +1 more source