Results 81 to 90 of about 4,964 (211)

Is the intention to use sport supplements a predictor of placebo and nocebo responding among athletes? [PDF]

, 2017
Background: Placebo and nocebo effects have been observed in relation to many interventions in sport. Given variance in response, a key question is whether individual difference variables identify likely ‘responders.’ Hypothetically, such a variable ...
Beedie, C., Hurst, P., Coleman, D., Foad, A.   +3 more
core  

Lost in Translation: Why Biologic Therapies for Intervertebral Disc Degeneration and Low Back Pain Have Not Reached the Clinic (Yet)

JOR SPINE, Volume 9, Issue 3, September 2026.
From preclinical promise to clinical translation in intervertebral disc degeneration (IDD). Robust preclinical evidence supports a range of biologic therapies, with consistent improvements in imaging, extracellular matrix composition, inflammation, and behavior.
Luca Ambrosio, Jordy Schol, Clara Ruiz‐Fernandez, Vincenzo Denaro, Gianluca Vadalà, Daisuke Sakai   +5 more
wiley   +1 more source

Switching Patients from Originator to Biosimilar Medications in Rheumatoid Arthritis: Limiting the ‘Nocebo’ Effect [PDF]

, 2017
Biosimilars have been available in Europe since 2006, and biosimilars of monoclonal antibodies since 2013, and are now a widespread clinical reality.
Biogen
core  

Placebo and nocebo effects in the neurological practice

Arquivos de Neuro-Psiquiatria, 2015
Knowledge of placebo and nocebo effects is essential to identify their influence on the results in clinical practice and clinical trials, and thereby properly interpret their results.
Caroline Bittar, Osvaldo J.M. Nascimento
doaj   +1 more source

Differential Impact of Pharmacokinetic and Pharmacodynamic Variability on Response to Combination Therapy

Pharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.
ABSTRACT Interindividual variability (IIV) in drug response complicates both fixed‐dose design and individualized therapy. Understanding how pharmacokinetic (PK) and pharmacodynamic (PD) processes jointly shape this variability is essential, particularly in combination therapy, where multiple interacting pathways influence outcomes. This study employed
Kuteesa R. Bisaso, Ronald Kadada Karyaburo, Jackson K. Mukonzo, Ene I. Ette   +3 more
wiley   +1 more source

FG. The nocebo effect and its relevance for clinical practice. Psychosom Med [PDF]

, 2020
Negative expectations deriving from the clinical encounter can produce negative outcomes, known as nocebo effects. Specifically, research on the nocebo effect indicates that information disclosure about potential side effects can itself contribute to ...
M.D Luana Colloca, Ph.D Franklin G Miller   +1 more
core  

Nocebo Effect in patients with Adverse Drug Reactions: The Role of Emotion Regulation

Mediterranean Journal of Clinical Psychology, 2019
Patients who have experienced adverse drug reactions (ADRs) can show some psychological problems both pre-existing than consequently the reactions.
Mara Donatella Fiaschi, Susanna Voltolini, Patrizia Velotti, Fabiola Bizzi   +3 more
doaj   +1 more source

No Evidence for Seasonal Variations in Fatigue, Sleepiness and Insomnia Symptoms: Spring Fatigue Is a Cultural Phenomenon Rather Than a Seasonal Syndrome

Journal of Sleep Research, Volume 35, Issue 4, August 2026.
ABSTRACT Although not as prominent as in other animals, humans also experience seasonal variations in sleep duration and circadian processes. These variations are likely primarily driven by changes in photoperiod length. Anecdotally, many people report experiencing fatigue and low energy levels, particularly during spring in Germany, Switzerland and ...
Christine Blume, Albrecht Vorster
wiley   +1 more source

Cholecystokinin input from the anterior cingulate cortex to the lateral periaqueductal gray mediates nocebo pain behavior in mice

Nature Communications
The nocebo effect, opposite of the better-known placebo effect, in which anticipation of harm worsens pain and other symptoms, is increasingly thought to be responsible for poor clinical outcomes.
Sandra J. Poulson, Aleksandrina Skvortsova, Fatama Tuz Zahra, Damien C. Boorman, Seyed Asaad Karimi, Lisiê V. Paz, Wanning Cui, Antonietta Mandatori, Jacob Burek, Zahra Siddiqi, Maryam I. Fazili, Shivani R. Gami, Oakley B. Morgan, Mélanie Di Maria, Anton Dinh, Lianfang Liang, Robert Contofalsky, Jeffrey S. Mogil, Loren J. Martin   +18 more
doaj   +1 more source

Psychological Factors and Treatment Experiences Associated With Chemotherapy Side‐Effect Expectations and Symptom Severity: A Prospective Longitudinal Study

Cancer Medicine, Volume 15, Issue 7, July 2026.
ABSTRACT Background Patients' expectations may influence how chemotherapy side effects are perceived and could contribute to symptom amplification. Psychological distress and prior treatment experiences are assumed to shape these expectations, yet their interplay and impact on side‐effect burden remain unclear.
Miriam Grapp, Kristin Lichtenberg, Marcel Wilhelm, Hans‐Christoph Friederich, Till Johannes Bugaj   +4 more
wiley   +1 more source