Nocebo response intensity and influencing factors in the randomized clinical trials of irritable bowel syndrome: A systematic review and meta-analysis [PDF]
Frontiers in Medicine, 2022 ObjectiveTo estimate the magnitude of the nocebo response and explore its influencing factors in irritable bowel syndrome (IBS).MethodsThe PubMed, Embase, and Cochrane Library databases were searched up to March 2021.
Ruijie Li +9 more
doaj +4 more sources
The concept of placebo/nocebo response and effect [PDF]
EULAR Rheumatology Open: The placebo response is different from the placebo effect. Whereas the placebo response is the global response to a placebo, including spontaneous remission, regression to the mean, patients’ and experimenters’ biases, possible effects of ...
Fabrizio Benedetti
doaj +3 more sources
A systematic review of sex differences in the placebo and the nocebo effect [PDF]
Journal of Pain Research, 2017 Sara M Vambheim,1 Magne Arve Flaten2 1Department of Psychology, UiT, The Arctic University of Norway, Tromsø, 2Department of Psychology, Norwegian University of Science and Technology (NTNU), Trondheim, Norway Objectives: The present review ...
Vambheim SM, Flaten MA
doaj +4 more sources
Placebo and nocebo effects on pain through the lens of the predictive brain: Neurobiological mechanisms and translational implications. [PDF]
Exp PhysiolAbstract Placebo and nocebo effects on pain provide a model for investigating how cognitive and contextual factors modulate the physiological processes underlying nociception and its regulation. However, existing accounts remain fragmented and lack a unifying mechanistic framework linking brain, behaviour and autonomic responses.
Zamfira DA +4 more
europepmc +2 more sources
A Comprehensive Scientometric Analysis of Placebo and Nocebo Effects in Pain Research: From Placebo Mechanisms to Clinical Trials. [PDF]
J Eval Clin PractABSTRACT Placebo and nocebo phenomena are central in neuroscience, psychology, and clinical research, yet comprehensive bibliometric analyses remain limited. This study mapped placebo and nocebo research in pain, distinguishing mechanistic studies from randomised controlled trials (RCTs), using data from the Web of Science Core Collection up to March ...
Borghesi F +7 more
europepmc +2 more sources
Nocebo in Biosimilars and Generics in Neurology: A Systematic Review
Frontiers in Pharmacology, 2019 Background: Nocebo refers to adverse events related to patients’ negative expectations and previous experiences, mediated by several neurobiological pathways within the brain.
Ioanna Spanou +2 more
doaj +3 more sources
The physiology of survival: From the third man to placebo escape hatch? [PDF]
Exp PhysiolExperimental Physiology, EarlyView.
Marino FE, Marino AF.
europepmc +2 more sources
Effect of enhanced support for coping with side effects during medication counselling on the nocebo effect in patients with advanced lung cancer receiving initial chemotherapy: protocol for a multicentre exploratory open-label randomised controlled trial [PDF]
BMJ OpenIntroduction Chemotherapy-induced nausea and vomiting (CINV) is a common symptom in cancer, and it is one of the distressing symptoms in patients with cancer receiving chemotherapy.
Yoshinobu Matsuda +6 more
doaj +2 more sources
The High-Risk Model of Threat Perception Modulates Learning of Placebo and Nocebo Effects and Functional Somatic Disorders [PDF]
Brain SciencesThreat activation or deactivation in the brain–body is associated with learned nocebo or placebo somatic effects induced by fake invasive medical–surgical procedures.
Ian Wickramasekera
doaj +2 more sources
Beyond the evidence: The cervical collar as cultural artefact [PDF]
Scandinavian Journal of Trauma, Resuscitation and Emergency MedicineBackground Cervical collar application remains prevalent in trauma care despite the absence of evidence of neurological benefit from spinal immobilisation.
Tim Nutbeam
doaj +2 more sources