Results 1 to 10 of about 9,513,177 (193)

Nocebo response intensity and influencing factors in the randomized clinical trials of irritable bowel syndrome: A systematic review and meta-analysis [PDF]

Frontiers in Medicine, 2022
ObjectiveTo estimate the magnitude of the nocebo response and explore its influencing factors in irritable bowel syndrome (IBS).MethodsThe PubMed, Embase, and Cochrane Library databases were searched up to March 2021.
Ruijie Li, Fuping Chen, Xuanxuan He, Yuqing Feng, Qiaoqiao Pei, Dongke Wang, Xinghuang Liu, Jinsong Liu, Xiaohua Hou, Tao Bai   +9 more
doaj   +5 more sources

The concept of placebo/nocebo response and effect

EULAR Rheumatology Open
: The placebo response is different from the placebo effect. Whereas the placebo response is the global response to a placebo, including spontaneous remission, regression to the mean, patients’ and experimenters’ biases, possible effects of ...
Fabrizio Benedetti
doaj   +3 more sources

The High-Risk Model of Threat Perception Modulates Learning of Placebo and Nocebo Effects and Functional Somatic Disorders [PDF]

Brain Sciences
Threat activation or deactivation in the brain–body is associated with learned nocebo or placebo somatic effects induced by fake invasive medical–surgical procedures.
Ian Wickramasekera
doaj   +3 more sources

Between placebo and nocebo: Response to control treatment is mediated by amygdala activity and connectivity. [PDF]

Eur J Pain, 2020
In experimental placebo and nocebo studies, neutral control treatments are often administered for comparison with active treatments, but are of little interest, as, on average, they result in little change.
Egorova N, Benedetti F, Gollub RL, Kong J.   +3 more
europepmc   +2 more sources

Nocebo Response in Attention Deficit Hyperactivity Disorder: Meta-Analysis and Meta-Regression of 105 Randomized Clinical Trials

Journal of Attention Disorders, 2022
Objective: To determine nocebo response in ADHD, identify covariates modifying nocebo response, and study the relationship between nocebo response and drug safety. Method: Systematic review of randomized, double-blind, placebo-controlled clinical trials (
Magi Farré, Xavier Castells, Xavier Castells   +2 more
exaly   +2 more sources

Nocebo response intensity and influencing factors in the randomized clinical trials of functional dyspepsia: A systematic review and meta‐analysis

Journal of Digestive Diseases, 2023
In this study we aimed to evaluate the nocebo response rate in patients with functional dyspepsia (FD) and to explore its influencing factors.
Tao Bai
exaly   +2 more sources

The placebo response rate and nocebo events in obesity pharmacological trials. A systematic review and meta-analysis

EClinicalMedicine, 2022
Summary: Background: There is a growing number of trials examining the effectiveness of pharmacotherapies for obesity, however, little is known about placebo and nocebo effect in these trials. Hence, we sought to examine the effect of placebo in obesity
Yip Han Chin, Cheng Han Ng, Nicholas WS Chew, Gwyneth Kong, Wen Hui Lim, Darren Jun Hao Tan, Kai En Chan, Ansel Tang, Daniel Q Huang, Mark Y Chan, Gemma Figtree, Jiong-Wei Wang, Asim Shabbir, Chin Meng Khoo, Vincent Wai-Sun Wong, Dan Yock Young, Mohammad Shadab Siddiqui, Mazen Noureddin, Arun Sanyal, David E. Cummings, Nicholas Syn, Mark Dhinesh Muthiah   +21 more
doaj   +2 more sources

Evidence of a Media-Induced Nocebo Response Following a Nationwide Antidepressant Drug Switch

Clinical Psychology in Europe, 2019
[Background] In 2017, patients on a generic or branded antidepressant venlafaxine were switched to a new generic formulation (Enlafax). In February and April 2018, two major NZ media outlets ran stories about the new generic being less effective ...
Kate MacKrill, Greg D. Gamble, Debbie J. Bean, Tim Cundy, Keith J. Petrie   +4 more
doaj   +2 more sources

Effect of enhanced support for coping with side effects during medication counselling on the nocebo effect in patients with advanced lung cancer receiving initial chemotherapy: protocol for a multicentre exploratory open-label randomised controlled trial [PDF]

BMJ Open
Introduction Chemotherapy-induced nausea and vomiting (CINV) is a common symptom in cancer, and it is one of the distressing symptoms in patients with cancer receiving chemotherapy.
Yoshinobu Matsuda, Hideaki Hasuo, Ryohei Fujii, Miyuki Okada, Haruka Ishikura, Yusuke Imai, Risako Muraoka   +6 more
doaj   +2 more sources

Nocebo in Biosimilars and Generics in Neurology: A Systematic Review

Frontiers in Pharmacology, 2019
Background: Nocebo refers to adverse events related to patients’ negative expectations and previous experiences, mediated by several neurobiological pathways within the brain.
Ioanna Spanou, Theodoros Mavridis, Dimos D. Mitsikostas   +2 more
doaj   +3 more sources