Results 21 to 30 of about 3,456 (197)

Beyond the evidence: The cervical collar as cultural artefact [PDF]

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Background Cervical collar application remains prevalent in trauma care despite the absence of evidence of neurological benefit from spinal immobilisation.
Tim Nutbeam
doaj   +2 more sources

Placebo and nocebo responses in restless legs syndrome [PDF]

Neurology, 2017
To estimate the placebo and nocebo responses in restless legs syndrome (RLS) and explore their determinants.Databases were searched up to October 2015. Randomized, double-blind, placebo-controlled trials of patients with RLS were included if quantitative data were extractable in the placebo arm.
Silva, Maria A., Duarte, Gonçalo Silva, Camara, Raquel, Rodrigues, Filipe Brogueira, Fernandes, Ricardo M., Abreu, Daisy, Mestre, Tiago, Costa, João, Trenkwalder, Claudia, Ferreira, Joaquim J   +9 more
openaire   +5 more sources

Between placebo and nocebo: Response to control treatment is mediated by amygdala activity and connectivity. [PDF]

Eur J Pain, 2020
BACKGROUND: In experimental placebo and nocebo studies, neutral control treatments are often administered for comparison with active treatments, but are of little interest, as, on average, they result in little change.
Egorova N, Benedetti F, Gollub RL, Kong J.   +3 more
europepmc   +2 more sources

Nocebo Effect on Pain-Related Autonomic Responses in a State of Experimentally-Induced Sensitization. [PDF]

Eur J Pain
ABSTRACTBackgroundEnhanced pain‐related autonomic responses were reported after experimentally‐induced secondary mechanical hyperalgesia (SMH) in healthy individuals as well as in a variety of chronic pain cohorts. Stimulus‐induced autonomic responses can also be modulated by positive and negative expectations towards the applied stimulus.
Allmendinger F, Rosner J, Egger T, Scheuren PS, Hubli M.   +4 more
europepmc   +4 more sources

Sex Differences in the Blood Oxygen Level-Dependent Signal to Placebo Analgesia and Nocebo Hyperalgesia in Experimental Pain: A Functional MRI Study

Frontiers in Behavioral Neuroscience, 2021
ObjectivePlacebo as well as nocebo responses are widely found in scientific research and clinical practice. Growing evidence suggests sex differences in placebo as well as nocebo responses.
Yu Shi, Yu Shi, Hongrui Zhan, Hongrui Zhan, Yanyan Zeng, Yanyan Zeng, Shimin Huang, Shimin Huang, Guiyuan Cai, Guiyuan Cai, Jianming Yang, Wen Wu, Wen Wu   +12 more
doaj   +1 more source

New Insights into the Placebo and Nocebo Responses [PDF]

Neuron, 2008
In modern medicine, the placebo response or placebo effect has often been regarded as a nuisance in basic research and particularly in clinical research. The latest scientific evidence has demonstrated, however, that the placebo effect and the nocebo effect, the negative effects of placebo, stem from highly active processes in the brain that are ...
Enck, Paul, Benedetti, Fabrizio, Schedlowski, Manfred   +2 more
openaire   +3 more sources

Brain Network to Placebo and Nocebo Responses in Acute Experimental Lower Back Pain: A Multivariate Granger Causality Analysis of fMRI Data

Frontiers in Behavioral Neuroscience, 2021
Background and Objective: Placebo and nocebo responses are widely observed. Herein, we investigated the nocebo hyperalgesia and placebo analgesia responses in brain network in acute lower back pain (ALBP) model using multivariate Granger causality ...
Yu Shi, Shaoye Cui, Yanyan Zeng, Shimin Huang, Guiyuan Cai, Jianming Yang, Wen Wu   +6 more
doaj   +1 more source

Nonconscious activation of placebo and nocebo pain responses [PDF]

Proceedings of the National Academy of Sciences, 2012
The dominant theories of human placebo effects rely on a notion that consciously perceptible cues, such as verbal information or distinct stimuli in classical conditioning, provide signals that activate placebo effects. However, growing evidence suggest that behavior can be triggered by stimuli presented outside of conscious awareness.
Jensen, Karin B., Kaptchuk, Ted J., Kirsch, Irving, Raicek, Jacqueline, Lindstrom, Kara M., Berna, Chantal, Gollub, Randy Lyanne, Ingvar, Martin, Kong, Jian   +8 more
openaire   +3 more sources

Understanding Placebo and Nocebo Responses for Pain Management [PDF]

Current Pain and Headache Reports, 2014
Placebo analgesia makes individuals experience relief of their pain simply by virtue of the anticipation of a benefit. A reduction of pain can occur also when placebos follow the administration of active and effective painkillers. In fact, studies indicate that placebos mimic the action of active treatments and promote the endogenous release of opioids
Luana, Colloca, Christian, Grillon
openaire   +2 more sources

Placebo and nocebo phenomena from the perspective of evidence based and person centered medicine [PDF]

Hospital Pharmacology, 2017
Introduction: Placebo and nocebo phenomena in pharmacology are very important, but controversial issues from the perspective of evidence-based medicine (EBM) in many ways.
Jakovljević Miro I.
doaj   +1 more source