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Frontiers in Behavioral Neuroscience, 2021 ObjectivePlacebo as well as nocebo responses are widely found in scientific research and clinical practice. Growing evidence suggests sex differences in placebo as well as nocebo responses.
Yu Shi +12 more
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Frontiers in Behavioral Neuroscience, 2021 Background and Objective: Placebo and nocebo responses are widely observed. Herein, we investigated the nocebo hyperalgesia and placebo analgesia responses in brain network in acute lower back pain (ALBP) model using multivariate Granger causality ...
Yu Shi +6 more
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New Insights into the Placebo and Nocebo Responses [PDF]
Neuron, 2008 In modern medicine, the placebo response or placebo effect has often been regarded as a nuisance in basic research and particularly in clinical research. The latest scientific evidence has demonstrated, however, that the placebo effect and the nocebo effect, the negative effects of placebo, stem from highly active processes in the brain that are ...
Enck, Paul +2 more
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Nonconscious activation of placebo and nocebo pain responses [PDF]
Proceedings of the National Academy of Sciences, 2012 The dominant theories of human placebo effects rely on a notion that consciously perceptible cues, such as verbal information or distinct stimuli in classical conditioning, provide signals that activate placebo effects. However, growing evidence suggest that behavior can be triggered by stimuli presented outside of conscious awareness.
Jensen, Karin B. +8 more
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Understanding Placebo and Nocebo Responses for Pain Management [PDF]
Current Pain and Headache Reports, 2014 Placebo analgesia makes individuals experience relief of their pain simply by virtue of the anticipation of a benefit. A reduction of pain can occur also when placebos follow the administration of active and effective painkillers. In fact, studies indicate that placebos mimic the action of active treatments and promote the endogenous release of opioids
Luana, Colloca, Christian, Grillon
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Trait responsiveness to verbal suggestions predicts nocebo responding: A meta-analysis [PDF]
British Journal of Health Psychology, 2023 Abstract Nocebo responding involves the experience of adverse health outcomes in response to contextual cues. These deleterious responses impact numerous features of mental and physical health but are characterized by pronounced heterogeneity.
Madeline V. Stein +4 more
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Placebo or Nocebo Interventions as Affected by Hypnotic Susceptibility
Applied Sciences, 2023 The purpose of the present study was to examine placebo and nocebo effects under hypnotic analgesia in lowly hypnotizable (LH) and highly hypnotizable (HH) subjects.
Yair Sharav, Yaron Haviv, Michael Tal
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Influence of the behaviour pattern on the nocebo response of healthy volunteers. [PDF]
British Journal of Clinical Pharmacology, 1995 The occurrence of a nocebo effect after placebo administration to healthy volunteers in a Phase I trial was analysed according to their type of personality (Bortner Rating Scale). More subjects with a behaviour pattern A (competitive and aggressive) (50%) described subjective side effects of the placebo than type B subjects (17%, P = 0.03).
M. Drici +4 more
semanticscholar +3 more sources
Placebo and nocebo phenomena from the perspective of evidence based and person centered medicine [PDF]
Hospital Pharmacology, 2017 Introduction: Placebo and nocebo phenomena in pharmacology are very important, but controversial issues from the perspective of evidence-based medicine (EBM) in many ways.
Jakovljević Miro I.
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European Headache Federation recommendations for placebo and nocebo terminology
The Journal of Headache and Pain, 2020 Background and aim Despite recent publications, practitioners remain unfamiliar with the current terminology related to the placebo and nocebo phenomena observed in clinical trials and practice, nor with the factors that modulate them.
Dimos D. Mitsikostas +17 more
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