Results 41 to 50 of about 3,074 (167)

DISCONTINUATION RATES FOLLOWING A SWITCH FROM A REFERENCE TO A BIOSIMILAR BIOLOGIC IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE: A SYSTEMATIC REVIEW AND META-ANALYSIS [PDF]

Arquivos de Gastroenterologia, 2020
BACKGROUND: Biologics have revolutionized the treatment of inflammatory bowel disease (IBD). However, these drugs had a significant influence on treatment-related costs, which resulted in the development of biosimilars.
Natália Sousa Freitas QUEIROZ, Rogerio SAAD-HOSSNE, Renata de Sá Brito FRÓES, Francisco Guilherme Cancela e PENNA, Stefania Burjack GABRIEL, Adalberta Lima MARTINS, Fabio Vieira TEIXEIRA   +6 more
doaj   +1 more source

PO104 Placebo and nocebo responses in rls: a meta-analysis [PDF]

Journal of Neurology, Neurosurgery & Psychiatry, 2017
Objective Our goals were to estimate the placebo and nocebo responses in restless legs syndrome (RLS). Methods Databases were searched up to October 2015. Randomised, double-blind, placebo-controlled trials of RLS patient were included. ‘Placebo response’ was defined as the within-group change from baseline, using any scale measuring RLS severity or
Rodrigues, Filipe Brogueira, Duarte, Gonçalo Silva, Silva, Maria A., Fernandes, Ricardo M., Abreu, Daisy, Mestre, Tiago, Costa, João, Trenkwalder, Claudia, Ferreira, Joaquim J   +8 more
openaire   +2 more sources

What Do Placebo and Nocebo Effects Have to Do With Health Equity? The Hidden Toll of Nocebo Effects on Racial and Ethnic Minority Patients in Clinical Care

Frontiers in Psychology, 2021
A placebo effect is a positive clinical response to non-specific elements of treatment with a sham or inert replica of a drug, device, or surgical intervention. There is considerable evidence that placebo effects are driven by expectation of benefit from
Hailey E. Yetman, Nevada Cox, Shelley R. Adler, Kathryn T. Hall, Kathryn T. Hall, Valerie E. Stone, Valerie E. Stone   +6 more
doaj   +1 more source

Qualitative StuNocebo Phenomenon (NP) Involved in Doctor-Patient Communication [PDF]

International Journal of Health Policy and Management, 2014
Background Doctor-patient communication has far reaching influences on the overall well-being of the patients. Words are powerful tools in the doctor’s armamentarium, having both healing as well as harming effects.
Bushra Ashraf, Muhammad Saaiq , Khaleeq Uz-Zaman   +2 more
doaj   +1 more source

Preventing adverse events of chemotherapy for gastrointestinal cancer by educating patients about the nocebo effect: a randomized-controlled trial

BMC Cancer, 2022
Background Adverse events of chemotherapy may be caused by pharmacodynamics or psychological factors such as negative expectations, which constitute nocebo effects. In a randomized controlled trial, we examined whether educating patients about the nocebo
T. Michnevich, Y. Pan, A. Hendi, K. Oechsle, A. Stein, Y. Nestoriuc   +5 more
doaj   +1 more source

Nonmedical Switching From Originators to Biosimilars: Does the Nocebo Effect Explain Treatment Failures and Adverse Events in Rheumatology and Gastroenterology?

Rheumatology and Therapy, 2020
The act of nonmedical switching, defined as switching stable patients who are generally doing well with their current therapy from an originator biologic to its biosimilar, has been endorsed as a reasonable treatment strategy.
Roy Fleischmann, Vipul Jairath, Eduardo Mysler, Dave Nicholls, Paul Declerck   +4 more
doaj   +1 more source

Conditioned Placebo- and Nocebo-Like Effects in Adolescents: The Role of Conscious Awareness, Sensory Discrimination, and Executive Function

Frontiers in Psychiatry, 2020
Background: Conditioning is a key mechanism of placebo and nocebo effects in adults. Little is known about the underlying mechanisms of placebo and nocebo effects in youth and how they might be influenced by conscious awareness and cognitive abilities ...
Regula Neuenschwander, Regula Neuenschwander, Ella Weik, Christine M. Tipper, Karin Jensen, Tim F. Oberlander   +5 more
doaj   +1 more source

How the number of learning trials affects placebo and nocebo responses [PDF]

Pain, 2010
Conditioning procedures are used in many placebo studies because evidence suggests that conditioning-related placebo responses are usually more robust than those induced by verbal suggestions alone. However, it has not been shown whether there is a causal relation between the number of conditioning trials and the resistance to extinction of placebo and
Colloca L, Petrovic P, Wager TD, Ingvar M, BENEDETTI, Fabrizio   +4 more
openaire   +3 more sources

No Reason to Feel Sick? Nocebo Responses in the Placebo Arms of Experimental Endotoxemia Studies

Frontiers in Psychiatry, 2019
Adverse side effects are reported by a large proportion of patients undergoing medical treatment in clinical practice or clinical trials. Nocebo effects, induced by negative treatment expectancies, can contribute to negative patient-reported outcomes but
Sven Benson, Sigrid Elsenbruch
doaj   +1 more source

Does electromagnetic hypersensitivity originate from nocebo responses? Indications from a qualitative study [PDF]

Bioelectromagnetics, 2015
Idiopathic Environmental Intolerance attributed to Electromagnetic Fields (IEI‐EMF) is a condition in which symptoms are attributed to electromagnetic field (EMF) exposure. As electro‐hypersensitive (EHS) people have repeatedly been observed, during provocation trials, to report symptoms following perceived rather than actual exposure, the hypothesis ...
openaire   +3 more sources