Results 41 to 50 of about 5,065,669 (199)

Nonmedical Switching From Originators to Biosimilars: Does the Nocebo Effect Explain Treatment Failures and Adverse Events in Rheumatology and Gastroenterology?

Rheumatology and Therapy, 2020
The act of nonmedical switching, defined as switching stable patients who are generally doing well with their current therapy from an originator biologic to its biosimilar, has been endorsed as a reasonable treatment strategy.
Roy Fleischmann, Vipul Jairath, Eduardo Mysler, Dave Nicholls, Paul Declerck   +4 more
doaj   +1 more source

Conditioned Placebo- and Nocebo-Like Effects in Adolescents: The Role of Conscious Awareness, Sensory Discrimination, and Executive Function

Frontiers in Psychiatry, 2020
Background: Conditioning is a key mechanism of placebo and nocebo effects in adults. Little is known about the underlying mechanisms of placebo and nocebo effects in youth and how they might be influenced by conscious awareness and cognitive abilities ...
Regula Neuenschwander, Regula Neuenschwander, Ella Weik, Christine M. Tipper, Karin Jensen, Tim F. Oberlander   +5 more
doaj   +1 more source

A neural mechanism of direct and observational conditioning for placebo and nocebo responses [PDF]

NeuroImage, 2019
Classical theories suggest placebo analgesia and nocebo hyperalgesia are based on expectation and conditioned experience. Whereas the neural mechanism of how expectation modulates placebo and nocebo effects during pain anticipation have been extensively studied, little is known about how experience may change brain networks to produce placebo and ...
Yiheng Tu, Joel Park, Seppo P. Ahlfors, Sheraz Khan 0002, Natalia Egorova, Courtney Amanda Lang, Jin Cao, Jian Kong   +7 more
openaire   +4 more sources

Placebo and Nocebo Effects Are Defined by Opposite Opioid and Dopaminergic Responses [PDF]

Archives of General Psychiatry, 2008
Placebo and nocebo effects, the therapeutic and adverse effects, respectively, of inert substances or sham procedures, represent serious confounds in the evaluation of therapeutic interventions. They are also an example of cognitive processes, particularly expectations, capable of influencing physiology.To examine the contribution of 2 different ...
David J, Scott, Christian S, Stohler, Christine M, Egnatuk, Heng, Wang, Robert A, Koeppe, Jon-Kar, Zubieta   +5 more
openaire   +2 more sources

Relational autonomy, maternalism, and the nocebo effect [PDF]

, 2017
In their target article, Menkes et al. suggest that the nocebo effect, in which an individual experiences an adverse effect of medical treatment due to negative expectations, occasions a dilemma between autonomy and nonmaleficence.
Niker, Fay, Specker Sullivan, Laura, Fay Niker, Laura Specker Sullivan   +3 more
core   +1 more source

Influence of the behaviour pattern on the nocebo response of healthy volunteers. [PDF]

British Journal of Clinical Pharmacology, 1995
The occurrence of a nocebo effect after placebo administration to healthy volunteers in a Phase I trial was analysed according to their type of personality (Bortner Rating Scale). More subjects with a behaviour pattern A (competitive and aggressive) (50%) described subjective side effects of the placebo than type B subjects (17%, P = 0.03).
M D, Drici, F, Raybaud, C, De Lunardo, P, Iacono, P, Gustovic   +4 more
openaire   +2 more sources

Does Sex/Gender Play a Role in Placebo and Nocebo Effects? Conflicting Evidence From Clinical Trials and Experimental Studies

Frontiers in Neuroscience, 2019
Sex has been speculated to be a predictor of the placebo and nocebo effect for many years, but whether this holds true or not has rarely been investigated.
Paul Enck, Sibylle Klosterhalfen
doaj   +1 more source

Nocebo response in attention-deficit/hyperactivity disorder:meta-analysis and meta-regression of 105 randomized

, 2022
BACKGROUND Nocebo response (worsening of clinical symptoms or the experiencing of treatment-emergent adverse effects when administering an inert substance) is relevant in both clinical practice and research due to role played in withdrawals and lack ...
Ramírez Saco, David
core   +1 more source

Putting the ‘Art’ Into the ‘Art of Medicine’: The Under-Explored Role of Artifacts in Placebo Studies

Frontiers in Psychology, 2020
Research in social psychology demonstrates that physical environmental factors – or “artifacts” such as provider clothing and office décor – can influence health outcomes.
Michael H. Bernstein, Cosima Locher, Cosima Locher, Tobias Kube, Tobias Kube, Sarah Buergler, Sif Stewart-Ferrer, Charlotte Blease, Charlotte Blease   +8 more
doaj   +1 more source

The placebo and nocebo effect on sports performance: A systematic review [PDF]

, 2019
This is an accepted manuscript of an article published by Taylor and Francis in European Journal of Sport Science on 20/08/2019, available online: https://www.tandfonline.com/doi/full/10.1080/17461391.2019.1655098 The accepted version of the publication
Foad, Abby, Raglin, John S., Lane, A., Raglin, John, Hettinga, F., Coleman, D., Szabo, Attila, Hettinga, Florentina, Raglin, J., Foad, A., Szabo, A., Hurst, Phillip, Coleman, Damian, Roelands, Bart, Roelands, B., Hurst, Philip, Schiphof-Godart, l., Beedie, C., Schipof-Godart, Lieke, Beedie, Chris, Lane, Andrew, Hurst, P.   +21 more
core   +1 more source