Results 41 to 50 of about 5,354,051 (164)

The placebo response rate and nocebo events in obesity pharmacological trials. A systematic review and meta-analysis

EClinicalMedicine, 2022
Summary: Background: There is a growing number of trials examining the effectiveness of pharmacotherapies for obesity, however, little is known about placebo and nocebo effect in these trials. Hence, we sought to examine the effect of placebo in obesity
Yip Han Chin, Cheng Han Ng, Nicholas WS Chew, Gwyneth Kong, Wen Hui Lim, Darren Jun Hao Tan, Kai En Chan, Ansel Tang, Daniel Q Huang, Mark Y Chan, Gemma Figtree, Jiong-Wei Wang, Asim Shabbir, Chin Meng Khoo, Vincent Wai-Sun Wong, Dan Yock Young, Mohammad Shadab Siddiqui, Mazen Noureddin, Arun Sanyal, David E. Cummings, Nicholas Syn, Mark Dhinesh Muthiah   +21 more
doaj   +1 more source

Is the intention to use sport supplements a predictor of placebo and nocebo responding among athletes? [PDF]

, 2017
Background: Placebo and nocebo effects have been observed in relation to many interventions in sport. Given variance in response, a key question is whether individual difference variables identify likely ‘responders.’ Hypothetically, such a variable ...
Beedie, C., Hurst, P., Coleman, D., Foad, A.   +3 more
core  

Time‐Resolved Multi‐Omics Identify Biomarkers of Immediate Reactions to mRNA Vaccination

Allergy, EarlyView.
We compared early vaccine‐induced immune and metabolic signatures and downstream immunity after second and booster BNT162b2 doses in participants with sARs, ISSRs, or no reactions. Neutrophil mobilization, antiviral programs, and robust anti‐S‐antibody responses occurred across reaction groups.
Ana Olivera, Benjamin Schwarz, Brittany Dulek, Ian S. LaCroix, Min Li, Lindsay Chatman, Muhammad B. Khalid, Ellen Zektser, Karen Laky, Stella Hartono, Eric Bohrnsen, Cole D. Kimzey, Eric Chu, Roa Harb, Pamela A. Frischmeyer‐Guerrerio   +14 more
wiley   +1 more source

Do psychological interventions in childhood and adolescence prevent later mental illness? A commentary on Vassard et al. (2026)

Journal of Child Psychology and Psychiatry, EarlyView.
Early intervention in youth mental health has long been assumed to confer long‐term benefits, altering developmental trajectories and reducing risk of later mental disorders. The 3‐year follow‐up of the Mind My Mind (MMM) trial challenges these assumptions.
Ian Kelleher
wiley   +1 more source

Research Review: No robust effects of Circle of Security‐Parenting (COSP) on parenting, parents, or children – a systematic review and meta‐analysis of randomized controlled trials

Journal of Child Psychology and Psychiatry, EarlyView.
Background Circle of Security‐Parenting (COSP) is one of the most popular attachment‐based preventive support programs for parents and children. More than 50,000 participants from different (para)professional disciplines have been trained in the formal COSP™ protocol. Methods In a preregistered meta‐analysis and synthesis of all eight randomized trials
Marian J. Bakermans‐Kranenburg, Megan Galbally, Erinn Hawkins, Marinus H. van IJzendoorn   +3 more
wiley   +1 more source

How Do Nocebo Phenomena Provide a Theoretical Framework for the COVID-19 Pandemic?

Frontiers in Psychology, 2020
The COVID-19 pandemic is a major health issue, which leads to psychological and behavioural changes. In particular, among various negative feelings, fear seems to be one of the main emotional reactions that can be as contagious as the virus itself.
Martina Amanzio, Martina Amanzio, Jeremy Howick, Massimo Bartoli, Giuseppina Elena Cipriani, Jian Kong   +5 more
doaj   +1 more source

Trait Neuroticism and the Nocebo Effect: The Mediating Role of Side‐Effect Expectations

Journal of Personality, EarlyView.
ABSTRACT Objective Neuroticism has not only been linked to heightened negative expectations and general somatic complaints but also to increased nocebo responses following medical treatments. Since side‐effect expectations are considered a main driver of nocebo responses, we tested whether side‐effect expectations mediate the neuroticism–nocebo ...
Anton Fischer, Li‐Ching Chuang, Nick Augustat, Pia von Blanckenburg, Erik M. Mueller   +4 more
wiley   +1 more source

Treatment journey in rheumatoid arthritis with biosimilars: from better access to good disease control through cost savings and prevention of nocebo effects

RMD Open, 2021
Early diagnosis and treatment of rheumatoid arthritis (RA) are of critical importance to halt the progression of the disease. Optimal use of advanced imaging techniques or biomarkers may facilitate early diagnosis of RA.
Bruno Fautrel, Josef S Smolen, Fabrizio Benedetti, Roberto Caporali, Thomas Doerner, Burkhard Pieper, Minjun Jang   +6 more
doaj   +1 more source

“Buprenorphine doesn't hold me”: Neurochemical afterlives of state violence and the struggle for meaning in addiction treatment

Medical Anthropology Quarterly, EarlyView.
Abstract This paper analyzes two disparate experiences of buprenorphine, a medication for opioid addiction, in California. Within the context of the U.S. War on Drugs and after decades of criminalization, buprenorphine represents a shift toward outpatient medical treatment of opioid addiction, but it has been unequally distributed and experienced ...
Lauren Textor
wiley   +1 more source

Placebo and Nocebo Effects in Patients With Takotsubo Cardiomyopathy and Heart-Healthy Controls

Frontiers in Psychiatry, 2019
The etiology of takotsubo cardiomyopathy (TTC)—a rare, reversible, and acquired form of cardiac diseases—is not yet fully explained. An exaggerated activation of the sympathetic-nervous-system (SNS) following stressful psychosocial life events is ...
Elisabeth Olliges, Simon Schneider, Georg Schmidt, Daniel Sinnecker, Daniel Sinnecker, Alexander Müller, Christof Burgdorf, Christof Burgdorf, Siegmund Braun, Stefan Holdenrieder, Hansjörg Ebell, Karl-Heinz Ladwig, Karl-Heinz Ladwig, Karin Meissner, Karin Meissner, Joram Ronel, Joram Ronel   +16 more
doaj   +1 more source