Results 51 to 60 of about 3,074 (167)

Nocebo in Biosimilars and Generics in Neurology: A Systematic Review

Frontiers in Pharmacology, 2019
Background: Nocebo refers to adverse events related to patients’ negative expectations and previous experiences, mediated by several neurobiological pathways within the brain.
Ioanna Spanou, Theodoros Mavridis, Dimos D. Mitsikostas   +2 more
doaj   +1 more source

The Influence of Expectation on Nondeceptive Placebo and Nocebo Effects

Pain Research and Management, 2018
Nondeceptive placebo has demonstrated its efficiency in clinical practice. Although the underlying mechanisms are still unclear, nondeceptive placebo effect and nondeceptive nocebo effect may be mediated by expectation.
Hua Wei, Lili Zhou, Huijuan Zhang, Jie Chen, Xuejing Lu, Li Hu   +5 more
doaj   +1 more source

Does Sex/Gender Play a Role in Placebo and Nocebo Effects? Conflicting Evidence From Clinical Trials and Experimental Studies

Frontiers in Neuroscience, 2019
Sex has been speculated to be a predictor of the placebo and nocebo effect for many years, but whether this holds true or not has rarely been investigated.
Paul Enck, Sibylle Klosterhalfen
doaj   +1 more source

Putting the ‘Art’ Into the ‘Art of Medicine’: The Under-Explored Role of Artifacts in Placebo Studies

Frontiers in Psychology, 2020
Research in social psychology demonstrates that physical environmental factors – or “artifacts” such as provider clothing and office décor – can influence health outcomes.
Michael H. Bernstein, Cosima Locher, Cosima Locher, Tobias Kube, Tobias Kube, Sarah Buergler, Sif Stewart-Ferrer, Charlotte Blease, Charlotte Blease   +8 more
doaj   +1 more source

A Neural Mechanism for Nonconscious Activation of Conditioned Placebo and Nocebo Responses [PDF]

Cerebral Cortex, 2014
Fundamental aspects of human behavior operate outside of conscious awareness. Yet, theories of conditioned responses in humans, such as placebo and nocebo effects on pain, have a strong emphasis on conscious recognition of contextual cues that trigger the response.
Jensen, Karin B., Kaptchuk, Ted, Kirsch, Irving, Gollub, Randy, Kong, Jian, Chen, Xiaoyan, Ingvar, Martin   +6 more
openaire   +3 more sources

The Effect of Positive Therapeutic Communication on Pain (POPAIN) and Anxiety During Arterial Blood Gas Standardized Procedures in the Emergency Department Compared to Traditional Communication: Protocol for a Monocentric Randomized Controlled Trial

JMIR Research Protocols, 2023
BackgroundIn the emergency department (ED), medical procedures, such as arterial blood gas (ABG) testing, can cause pain and high stress levels.
Thomas Schmutz, Christophe Le Terrier, Vincent Ribordy, Katia Iglesias, Youcef Guechi   +4 more
doaj   +1 more source

The placebo response rate and nocebo events in obesity pharmacological trials. A systematic review and meta-analysis

EClinicalMedicine, 2022
Summary: Background: There is a growing number of trials examining the effectiveness of pharmacotherapies for obesity, however, little is known about placebo and nocebo effect in these trials. Hence, we sought to examine the effect of placebo in obesity
Yip Han Chin, Cheng Han Ng, Nicholas WS Chew, Gwyneth Kong, Wen Hui Lim, Darren Jun Hao Tan, Kai En Chan, Ansel Tang, Daniel Q Huang, Mark Y Chan, Gemma Figtree, Jiong-Wei Wang, Asim Shabbir, Chin Meng Khoo, Vincent Wai-Sun Wong, Dan Yock Young, Mohammad Shadab Siddiqui, Mazen Noureddin, Arun Sanyal, David E. Cummings, Nicholas Syn, Mark Dhinesh Muthiah   +21 more
doaj   +1 more source

Placebo and Nocebo Effects Are Defined by Opposite Opioid and Dopaminergic Responses [PDF]

Archives of General Psychiatry, 2008
Placebo and nocebo effects, the therapeutic and adverse effects, respectively, of inert substances or sham procedures, represent serious confounds in the evaluation of therapeutic interventions. They are also an example of cognitive processes, particularly expectations, capable of influencing physiology.To examine the contribution of 2 different ...
David J, Scott, Christian S, Stohler, Christine M, Egnatuk, Heng, Wang, Robert A, Koeppe, Jon-Kar, Zubieta   +5 more
openaire   +2 more sources

Psilocybin in alcohol use disorder and comorbid depressive symptoms: Results from a feasibility randomized clinical trial

Addiction, EarlyView.
Abstract Background and Aims Psilocybin has emerged as a potential treatment for alcohol use disorder (AUD), but early efficacy data are inconsistent. Depression following alcohol detoxification significantly increases the risk of relapse. This pilot study aimed to evaluate the feasibility, acceptability, and preliminary efficacy of psilocybin‐assisted
Amandine Luquiens, Dahbia Belahda, Carine Graux, Noe Igounenc, Chris Serrand, Paul Rochefort, Thibault Mura, Felix Sergent   +7 more
wiley   +1 more source

Placebo and the law of identification

Frontiers in Psychiatry
Thousands of essays and studies have been published on placebo and nocebo. Yet, despite this plethora of information, we are not much closer to a comprehensive understanding of the fundamental mechanism producing placebo and nocebo effects than we were ...
Steve F. Bierman, Andrew Weil, Stephen Dahmer   +2 more
doaj   +1 more source