Results 51 to 60 of about 5,065,669 (199)

The Effect of Positive Therapeutic Communication on Pain (POPAIN) and Anxiety During Arterial Blood Gas Standardized Procedures in the Emergency Department Compared to Traditional Communication: Protocol for a Monocentric Randomized Controlled Trial

JMIR Research Protocols, 2023
BackgroundIn the emergency department (ED), medical procedures, such as arterial blood gas (ABG) testing, can cause pain and high stress levels.
Thomas Schmutz, Christophe Le Terrier, Vincent Ribordy, Katia Iglesias, Youcef Guechi   +4 more
doaj   +1 more source

The placebo response rate and nocebo events in obesity pharmacological trials. A systematic review and meta-analysis

EClinicalMedicine, 2022
Summary: Background: There is a growing number of trials examining the effectiveness of pharmacotherapies for obesity, however, little is known about placebo and nocebo effect in these trials. Hence, we sought to examine the effect of placebo in obesity
Yip Han Chin, Cheng Han Ng, Nicholas WS Chew, Gwyneth Kong, Wen Hui Lim, Darren Jun Hao Tan, Kai En Chan, Ansel Tang, Daniel Q Huang, Mark Y Chan, Gemma Figtree, Jiong-Wei Wang, Asim Shabbir, Chin Meng Khoo, Vincent Wai-Sun Wong, Dan Yock Young, Mohammad Shadab Siddiqui, Mazen Noureddin, Arun Sanyal, David E. Cummings, Nicholas Syn, Mark Dhinesh Muthiah   +21 more
doaj   +1 more source

Outcomes of adalimumab biosimilar nonmedical switches in children and young adults with inflammatory bowel disease

JPGN Reports, EarlyView.
Abstract Objectives Adalimumab biosimilars are as safe and effective compared to the originator. Adult patients with inflammatory bowel disease (IBD) who switched to a biosimilar have comparable outcomes, but pediatric data are limited. This study evaluates clinical outcomes of children and young adults with IBD following a nonmedical, insurance‐driven
Daniel Himelstein, Megan McNicol, Mahmoud Abdel‐Rasoul, Brendan M. Boyle, Hilary K. Michel, Ross Maltz   +5 more
wiley   +1 more source

Placebo and the law of identification

Frontiers in Psychiatry
Thousands of essays and studies have been published on placebo and nocebo. Yet, despite this plethora of information, we are not much closer to a comprehensive understanding of the fundamental mechanism producing placebo and nocebo effects than we were ...
Steve F. Bierman, Andrew Weil, Stephen Dahmer   +2 more
doaj   +1 more source

Psilocybin in alcohol use disorder and comorbid depressive symptoms: Results from a feasibility randomized clinical trial

Addiction, EarlyView.
Abstract Background and Aims Psilocybin has emerged as a potential treatment for alcohol use disorder (AUD), but early efficacy data are inconsistent. Depression following alcohol detoxification significantly increases the risk of relapse. This pilot study aimed to evaluate the feasibility, acceptability, and preliminary efficacy of psilocybin‐assisted
Amandine Luquiens, Dahbia Belahda, Carine Graux, Noe Igounenc, Chris Serrand, Paul Rochefort, Thibault Mura, Felix Sergent   +7 more
wiley   +1 more source

Time‐Resolved Multi‐Omics Identify Biomarkers of Immediate Reactions to mRNA Vaccination

Allergy, EarlyView.
We compared early vaccine‐induced immune and metabolic signatures and downstream immunity after second and booster BNT162b2 doses in participants with sARs, ISSRs, or no reactions. Neutrophil mobilization, antiviral programs, and robust anti‐S‐antibody responses occurred across reaction groups.
Ana Olivera, Benjamin Schwarz, Brittany Dulek, Ian S. LaCroix, Min Li, Lindsay Chatman, Muhammad B. Khalid, Ellen Zektser, Karen Laky, Stella Hartono, Eric Bohrnsen, Cole D. Kimzey, Eric Chu, Roa Harb, Pamela A. Frischmeyer‐Guerrerio   +14 more
wiley   +1 more source

How Do Nocebo Phenomena Provide a Theoretical Framework for the COVID-19 Pandemic?

Frontiers in Psychology, 2020
The COVID-19 pandemic is a major health issue, which leads to psychological and behavioural changes. In particular, among various negative feelings, fear seems to be one of the main emotional reactions that can be as contagious as the virus itself.
Martina Amanzio, Martina Amanzio, Jeremy Howick, Massimo Bartoli, Giuseppina Elena Cipriani, Jian Kong   +5 more
doaj   +1 more source

Cognitive behavioural therapy compared to control conditions in treating bulimia nervosa and binge‐eating disorder: A systematic review and meta‐analysis

British Journal of Clinical Psychology, EarlyView.
Abstract Objective Our systematic review and meta‐analysis aimed to investigate how Cognitive‐Behavioural Therapy (CBT) performs against control conditions, such as waiting‐list, self‐help interventions, psychological and pill placebos and treatment as usual (TAU) in Bulimia Nervosa (BN) and Binge Eating Disorder (BED).
Angeliki L. Sioziou, Anastasios Stefanou, Felicia Dimitrakopoulou, Menelaos Skarlatos, Andreas S. Lappas, Christina Mesiari, Aikaterini Argyrou, Evangelos Ntouros, Nikolaos Christodoulou, Vasilios‐Panteleimon Bozikas, Myrto Samara   +10 more
wiley   +1 more source

Treatment journey in rheumatoid arthritis with biosimilars: from better access to good disease control through cost savings and prevention of nocebo effects

RMD Open, 2021
Early diagnosis and treatment of rheumatoid arthritis (RA) are of critical importance to halt the progression of the disease. Optimal use of advanced imaging techniques or biomarkers may facilitate early diagnosis of RA.
Bruno Fautrel, Josef S Smolen, Fabrizio Benedetti, Roberto Caporali, Thomas Doerner, Burkhard Pieper, Minjun Jang   +6 more
doaj   +1 more source

Do psychological interventions in childhood and adolescence prevent later mental illness? A commentary on Vassard et al. (2026)

Journal of Child Psychology and Psychiatry, EarlyView.
Early intervention in youth mental health has long been assumed to confer long‐term benefits, altering developmental trajectories and reducing risk of later mental disorders. The 3‐year follow‐up of the Mind My Mind (MMM) trial challenges these assumptions.
Ian Kelleher
wiley   +1 more source