Results 61 to 70 of about 3,456 (197)

Nocebo Phenomena in Medicine

, 2012
Background: Nocebo phenomena are common in clinical practice and have recently become a popular topic of research and discussion among basic scientists, clinicians, and ethicists.
Ernil Hansen, Paul Enck, Hansen, Ernil, Winfried Häuser, Häuser, Winfried, Enck, Paul   +5 more
core   +1 more source

No Evidence for Seasonal Variations in Fatigue, Sleepiness and Insomnia Symptoms: Spring Fatigue Is a Cultural Phenomenon Rather Than a Seasonal Syndrome

Journal of Sleep Research, EarlyView.
ABSTRACT Although not as prominent as in other animals, humans also experience seasonal variations in sleep duration and circadian processes. These variations are likely primarily driven by changes in photoperiod length. Anecdotally, many people report experiencing fatigue and low energy levels, particularly during spring in Germany, Switzerland and ...
Christine Blume, Albrecht Vorster
wiley   +1 more source

Peripheral Inflammation and Sleep Loss Induce Coordinated Motivational Changes: An Experimental Two‐Hit Stress Model

Journal of Sleep Research, EarlyView.
ABSTRACT Sleep loss and low‐grade inflammation are common stressors that affect behaviour and recovery needs. To examine their separate and combined effects on motivation for everyday behaviours, we developed a two‐hit experimental model. Participants (N = 56, 31 women) completed three experimental visits: sleep saturation (two nights, 9 h in bed/night)
John Axelsson, Mats Lekander, Camilla I. Svensson, Nils Simon, Alexandra Kuliszkiewicz, Julie Lasselin, Leonie J. T. Balter   +6 more
wiley   +1 more source

Efectul placebo / nocebo în relația terapeutică [PDF]

, 2022
Background. The psychogenic component of the therapeutic relationship is critical in determining whether medication therapy is beneficial. The concepts of placebo and nocebo are highlighted in this way. Objective of the study. The goal of this research
Neculcea, Natalia
core  

Placebo and Nocebo Effects in Patients With Takotsubo Cardiomyopathy and Heart-Healthy Controls

Frontiers in Psychiatry, 2019
The etiology of takotsubo cardiomyopathy (TTC)—a rare, reversible, and acquired form of cardiac diseases—is not yet fully explained. An exaggerated activation of the sympathetic-nervous-system (SNS) following stressful psychosocial life events is ...
Elisabeth Olliges, Simon Schneider, Georg Schmidt, Daniel Sinnecker, Daniel Sinnecker, Alexander Müller, Christof Burgdorf, Christof Burgdorf, Siegmund Braun, Stefan Holdenrieder, Hansjörg Ebell, Karl-Heinz Ladwig, Karl-Heinz Ladwig, Karin Meissner, Karin Meissner, Joram Ronel, Joram Ronel   +16 more
doaj   +1 more source

Quantitative Sensory Testing Across Chronic Pain Conditions and Use in Special Populations

Frontiers in Pain Research, 2022
Chronic pain imposes a significant burden to the healthcare system and adversely affects patients' quality of life. Traditional subjective assessments, however, do not adequately capture the complex phenomenon of pain, which is influenced by a multitude ...
Kristen R. Weaver, Kristen R. Weaver, Mari A. Griffioen, Mari A. Griffioen, N. Jennifer Klinedinst, Elizabeth Galik, Ana C. Duarte, Luana Colloca, Luana Colloca, Barbara Resnick, Barbara Resnick, Susan G. Dorsey, Susan G. Dorsey, Cynthia L. Renn, Cynthia L. Renn   +14 more
doaj   +1 more source

Ischaemic pre‐conditioning improves workload, fatigue and recovery in team sport: A randomized, double‐blind, placebo‐controlled crossover trial

Experimental Physiology, EarlyView.
Abstract Ischaemic preconditioning (IPC) is reported to improve performance, fatigue and recovery, yet evidence in team‐sport settings remains limited. We examined the effects of repeated IPC on external workload, perceptual strain and recovery during ecologically valid Gaelic football training.
Lorcan Daly, Shane Farrell, Alexander Gamble   +2 more
wiley   +1 more source

Differential Impact of Pharmacokinetic and Pharmacodynamic Variability on Response to Combination Therapy

Pharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.
ABSTRACT Interindividual variability (IIV) in drug response complicates both fixed‐dose design and individualized therapy. Understanding how pharmacokinetic (PK) and pharmacodynamic (PD) processes jointly shape this variability is essential, particularly in combination therapy, where multiple interacting pathways influence outcomes. This study employed
Kuteesa R. Bisaso, Ronald Kadada Karyaburo, Jackson K. Mukonzo, Ene I. Ette   +3 more
wiley   +1 more source

Analgesia da placebo, anticipazione dolorifica e i possibili correlati neurali dell'effetto nocebo

Rivista Internazionale di Filosofia e Psicologia, 2018
The nocebo effect is a psychobiological effect that occurs when a negative psychosocial context that accompanies a therapy. Since the study of pain anticipation takes into account the temporal phase of the “expectation of hyperalgesia”, and considering ...
Sara Palermo
doaj   +1 more source

Financial Toxicity Associated with Biological Medicines: A Scoping Review

Clinical Pharmacology &Therapeutics, Volume 120, Issue 1, Page 81-93, July 2026.
Financial toxicity, defined as the economic burden experienced by patients due to medication and other healthcare costs and their consequences, such as material, psychosocial and behavioral effects, represents a significant concern for individuals receiving biological medicines.
Laura Sara Maria Saarukka, Kamilla Yamileva, Kari Linden, Anniina Simonen, Anna‐Riia Holmström   +4 more
wiley   +1 more source