Results 61 to 70 of about 3,074 (167)

Hypersensitivity to Excipients in Drugs: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT Drugs contain active pharmaceutical ingredients and excipients, compounds which enhance the pharmacokinetics, stability and palatability of the pharmaceutical formulation. While most drug hypersensitivity reactions (DHR) are caused by active ingredients, excipients may also be involved.
Lene H. Garvey, Knut Brockow, Annick Barbaud, Charlotte G. Mortz, Gianfranco Calogiuri, Asli Gelincik, Osman O. Yeğit, Alla Nakonechna, Annette Wagner, Rik Schrijvers, Toon Ieven   +10 more
wiley   +1 more source

Conscious Expectation and Unconscious Conditioning in Analgesic, Motor, and Hormonal Placebo/Nocebo Responses [PDF]

The Journal of Neuroscience, 2003
The placebo and nocebo effect is believed to be mediated by both cognitive and conditioning mechanisms, although little is known about their role in different circumstances. In this study, we first analyzed the effects of opposing verbal suggestions on experimental ischemic arm pain in healthy volunteers and on motor performance in Parkinsonian ...
BENEDETTI, Fabrizio, POLLO, Antonella, LOPIANO, Leonardo, LANOTTE, Michele Maria Rosario, VIGHETTI S., RAINERO, Innocenzo   +5 more
openaire   +3 more sources

How Do Nocebo Phenomena Provide a Theoretical Framework for the COVID-19 Pandemic?

Frontiers in Psychology, 2020
The COVID-19 pandemic is a major health issue, which leads to psychological and behavioural changes. In particular, among various negative feelings, fear seems to be one of the main emotional reactions that can be as contagious as the virus itself.
Martina Amanzio, Martina Amanzio, Jeremy Howick, Massimo Bartoli, Giuseppina Elena Cipriani, Jian Kong   +5 more
doaj   +1 more source

Midwifery Communication for Childbirth: A Practical Approach

Journal of Midwifery &Women's Health, EarlyView.
Abstract During labor and birth, inadvertent negative suggestions from care givers and support people are common and may lead to negative experiences known as nocebo effects. Counteracting nocebo effects with the use of effective communication techniques can reduce distress, enhance birth experiences, and improve health outcomes.
Julie‐Anne Fleet, Laura Whitburn, Elizabeth Newnham, Allan Cyna   +3 more
wiley   +1 more source

Treatment journey in rheumatoid arthritis with biosimilars: from better access to good disease control through cost savings and prevention of nocebo effects

RMD Open, 2021
Early diagnosis and treatment of rheumatoid arthritis (RA) are of critical importance to halt the progression of the disease. Optimal use of advanced imaging techniques or biomarkers may facilitate early diagnosis of RA.
Bruno Fautrel, Josef S Smolen, Fabrizio Benedetti, Roberto Caporali, Thomas Doerner, Burkhard Pieper, Minjun Jang   +6 more
doaj   +1 more source

Trait Neuroticism and the Nocebo Effect: The Mediating Role of Side‐Effect Expectations

Journal of Personality, EarlyView.
ABSTRACT Objective Neuroticism has not only been linked to heightened negative expectations and general somatic complaints but also to increased nocebo responses following medical treatments. Since side‐effect expectations are considered a main driver of nocebo responses, we tested whether side‐effect expectations mediate the neuroticism–nocebo ...
Anton Fischer, Li‐Ching Chuang, Nick Augustat, Pia von Blanckenburg, Erik M. Mueller   +4 more
wiley   +1 more source

No Evidence for Seasonal Variations in Fatigue, Sleepiness and Insomnia Symptoms: Spring Fatigue Is a Cultural Phenomenon Rather Than a Seasonal Syndrome

Journal of Sleep Research, EarlyView.
ABSTRACT Although not as prominent as in other animals, humans also experience seasonal variations in sleep duration and circadian processes. These variations are likely primarily driven by changes in photoperiod length. Anecdotally, many people report experiencing fatigue and low energy levels, particularly during spring in Germany, Switzerland and ...
Christine Blume, Albrecht Vorster
wiley   +1 more source

Peripheral Inflammation and Sleep Loss Induce Coordinated Motivational Changes: An Experimental Two‐Hit Stress Model

Journal of Sleep Research, EarlyView.
ABSTRACT Sleep loss and low‐grade inflammation are common stressors that affect behaviour and recovery needs. To examine their separate and combined effects on motivation for everyday behaviours, we developed a two‐hit experimental model. Participants (N = 56, 31 women) completed three experimental visits: sleep saturation (two nights, 9 h in bed/night)
John Axelsson, Mats Lekander, Camilla I. Svensson, Nils Simon, Alexandra Kuliszkiewicz, Julie Lasselin, Leonie J. T. Balter   +6 more
wiley   +1 more source

Placebo and Nocebo Effects in Patients With Takotsubo Cardiomyopathy and Heart-Healthy Controls

Frontiers in Psychiatry, 2019
The etiology of takotsubo cardiomyopathy (TTC)—a rare, reversible, and acquired form of cardiac diseases—is not yet fully explained. An exaggerated activation of the sympathetic-nervous-system (SNS) following stressful psychosocial life events is ...
Elisabeth Olliges, Simon Schneider, Georg Schmidt, Daniel Sinnecker, Daniel Sinnecker, Alexander Müller, Christof Burgdorf, Christof Burgdorf, Siegmund Braun, Stefan Holdenrieder, Hansjörg Ebell, Karl-Heinz Ladwig, Karl-Heinz Ladwig, Karin Meissner, Karin Meissner, Joram Ronel, Joram Ronel   +16 more
doaj   +1 more source

Quantitative Sensory Testing Across Chronic Pain Conditions and Use in Special Populations

Frontiers in Pain Research, 2022
Chronic pain imposes a significant burden to the healthcare system and adversely affects patients' quality of life. Traditional subjective assessments, however, do not adequately capture the complex phenomenon of pain, which is influenced by a multitude ...
Kristen R. Weaver, Kristen R. Weaver, Mari A. Griffioen, Mari A. Griffioen, N. Jennifer Klinedinst, Elizabeth Galik, Ana C. Duarte, Luana Colloca, Luana Colloca, Barbara Resnick, Barbara Resnick, Susan G. Dorsey, Susan G. Dorsey, Cynthia L. Renn, Cynthia L. Renn   +14 more
doaj   +1 more source