Results 1 to 10 of about 39 (39)
European Journal of Pain, Volume 30, Issue 8, September 2026.ABSTRACT Background Low back pain (LBP) is the leading cause of years lived with disability. While education is recommended by most guidelines, the type of language used can lead to a placebo or nocebo effect. This study aims to compare the short‐term effect of negative language versus positive language on physical and functional capacity in ...
Yves Schwendenmann +3 more
wiley +1 more source
Journal of Evaluation in Clinical Practice, Volume 32, Issue 6, September 2026.ABSTRACT Placebo and nocebo phenomena are central in neuroscience, psychology, and clinical research, yet comprehensive bibliometric analyses remain limited. This study mapped placebo and nocebo research in pain, distinguishing mechanistic studies from randomised controlled trials (RCTs), using data from the Web of Science Core Collection up to March ...
Francesca Borghesi +7 more
wiley +1 more source
Human Brain Mapping, Volume 47, Issue 10, July 2026.This ALE meta‐analysis of brain imaging studies published between 2014 and 2025 identified the caudate nucleus/lentiform nucleus as a core neural substrate of explicit outcome expectation effects, with the red nucleus emerging as an additional significant cluster.
Junnan Zhou +3 more
wiley +1 more source
Health Science Reports, Volume 9, Issue 6, June 2026.ABSTRACT Background Inflammatory pain is a widespread global health concern arising from complex molecular pathways triggered by a consequence of tissue damage and immune activation. It significantly impacts quality of life and functional outcomes, necessitating a comprehensive understanding of underlying mechanisms and multidisciplinary approaches for
Fatma Mohamed Elmansy +6 more
wiley +1 more source
Chronic Pain: Epidemiology, Pathophysiology, and Clinical Management
MedComm, Volume 7, Issue 5, May 2026.The multidimensional nature of chronic pain is illustrated through four interconnected domains. (Left) Epidemiology and Global Burden: Chronic pain affects approximately one in five individuals globally, contributing to a rising trend in disability‐adjusted life years (YLDs) and a significant socioeconomic impact.
Zhihao Shang +12 more
wiley +1 more source
European Journal of Pain, Volume 30, Issue 4, April 2026.ABSTRACT Background Pain‐related autonomic responses are increased after experimentally‐induced secondary mechanical hyperalgesia (SMH), as well as in a variety of chronic pain cohorts. In this state of sensitization, negative expectations further amplify these enhanced responses.
Florin Allmendinger +5 more
wiley +1 more source
Can Nocebo Effects Be Reduced via Open‐ and Closed‐Label Counterconditioning?
European Journal of Pain, Volume 30, Issue 3, March 2026.ABSTRACT Background The overwhelming evidence of nocebo effects adversely affecting the experience of physical symptoms, such as pain, puts emphasis on the study of possible strategies to reduce nocebo effects. Counterconditioning, during which a previously conditioned effect is reversed, has been shown to be a possible promising strategy in a previous
Simone Meijer +3 more
wiley +1 more source
Sensory Neuroscience, Volume 2, Issue 1, March 2026.Chronic pain reflects maladaptive network interactions across sensory, salience/affective, and descending modulatory pathways. We review evidence for non‐invasive brain stimulation—rTMS, tES, and low‐intensity focused ultrasound—highlighting modest, variable, and often short‐lived analgesic effects under conventional protocols.
Fabian Broecker, Sven Vanneste
wiley +1 more source
Novel Technologies for Exploring the Skin–Brain Axis
Advanced Sensor Research, Volume 5, Issue 2, February 2026.The skin–brain axis mediates bidirectional communication between cutaneous physiology and the nervous system, influencing sensation, inflammation, and disease. This review surveys emerging microsensor, nanosensor, and bioelectronic technologies integrated with advanced skin and neural models, highlighting multimodal, real‐time strategies to decode ...
Dahiana Mojena Medina, Francesca Santoro
wiley +1 more source
European Journal of Pain, Volume 29, Issue 9, October 2025.ABSTRACT Background Persistent mismatches between predicted and actual pain‐related signals, namely prediction errors (PEs), can cause maladaptive overestimation of pain intensity, a common feature of chronic pain states. Experimental protocols used to assess the contribution of central sensitisation (CS) to dysregulated prediction systems are lacking.
Federico Palmisani +4 more
wiley +1 more source