The Temporal Modulation of Nocebo Hyperalgesia in a Model of Sustained Pain [PDF]
Frontiers in Psychiatry, 2022 BackgroundThe direction and the magnitude of verbal suggestions have been shown to be strong modulators of nocebo hyperalgesia, while little attention has been given to the role of their temporal content. Here, we investigate whether temporal suggestions
Luca Buzzatti +2 more
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Placebo Analgesia, Nocebo Hyperalgesia, and the Cardiovascular System: A Qualitative Systematic Review [PDF]
Frontiers in Physiology, 2020 Background: Placebo/nocebo effects involve the autonomic nervous system, including cardiac activity, but studies have reported inconsistent findings on how cardiac activity is modulated following a placebo/nocebo effect. However, no systematic review has
Magne Arve Flaten, Hojjat Daniali
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Fear of pain potentiates nocebo hyperalgesia [PDF]
Journal of Pain Research, 2015 Per M Aslaksen,1 Peter S Lyby2 1Department of Psychology, Research Group for Cognitive Neuroscience, The Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway; 2Catosenteret Rehabilitation Center,
Aslaksen PM, Lyby PS
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How Negative Experience Influences the Brain: A Comprehensive Review of the Neurobiological Underpinnings of Nocebo Hyperalgesia [PDF]
Frontiers in Neuroscience, 2021 This comprehensive review summarizes and interprets the neurobiological correlates of nocebo hyperalgesia in healthy humans. Nocebo hyperalgesia refers to increased pain sensitivity resulting from negative experiences and is thought to be an important ...
Kaya J. Peerdeman +2 more
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Distinct Neural Networks Subserve Placebo Analgesia and Nocebo Hyperalgesia
NeuroImage, 2021 Neural networks involved in placebo analgesia and nocebo hyperalgesia processes have been widely investigated with neuroimaging methods. However, few studies have directly compared these two processes and it remains unclear whether common or distinct ...
Julia A Camilleri +2 more
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Nocebo hyperalgesia can be induced by classical conditioning without involvement of expectancy. [PDF]
PLoS ONE, 2020 Influential theoretical accounts take the position that classical conditioning can induce placebo effects through conscious expectancies. In the current study two different conditioning procedures (hidden and open) were used to separate expectancy from ...
Elżbieta A Bajcar +3 more
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Association of nocebo hyperalgesia and basic somatosensory characteristics in a large cohort [PDF]
Scientific Reports, 2021 Medical outcomes are strongly affected by placebo and nocebo effects. Prediction of who responds to such expectation effects has proven to be challenging.
Mari Hanna Feldhaus +3 more
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No evidence that attentional bias towards pain-related words is associated with verbally induced nocebo hyperalgesia: a dot-probe study [PDF]
PAIN Reports, 2021 . Introduction:. Placebo and nocebo effects in pain are well documented. One leading explanation is that instructions indicating that pain will either increase or decrease after receipt of a treatment give rise to expectations for increased or decreased ...
Matthew James Coleshill +2 more
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Personality Differences of Brain Networks in Placebo Analgesia and Nocebo Hyperalgesia: A Psychophysiological Interaction (PPI) Approach in fMRI [PDF]
Neural Plasticity, 2020 It is generally believed that the placebo response can elicit an analgesic effect, whilst the nocebo response can elicit a hyperalgesia effect in pain. Placebo analgesia and nocebo hyperalgesia effects are increasing concerns for researchers.
Yu Shi +7 more
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Sex Differences in the Blood Oxygen Level-Dependent Signal to Placebo Analgesia and Nocebo Hyperalgesia in Experimental Pain: A Functional MRI Study [PDF]
Frontiers in Behavioral Neuroscience, 2021 ObjectivePlacebo as well as nocebo responses are widely found in scientific research and clinical practice. Growing evidence suggests sex differences in placebo as well as nocebo responses.
Yu Shi +12 more
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