Results 31 to 40 of about 16,658 (137)

Short-Term Effect of Negative Verbal Language Versus Positive Verbal Language on Physical and Functional Capacity and Pain in People With Chronic Primary Low Back Pain. [PDF]

Eur J Pain
ABSTRACT Background Low back pain (LBP) is the leading cause of years lived with disability. While education is recommended by most guidelines, the type of language used can lead to a placebo or nocebo effect. This study aims to compare the short‐term effect of negative language versus positive language on physical and functional capacity in ...
Schwendenmann Y, Palacios PA, Descarreaux M, Marchand AA.   +3 more
europepmc   +2 more sources

Temporal structure of brain oscillations predicts learned nocebo responses to pain

Scientific Reports, 2021
This study aimed to identify electrophysiological correlates of nocebo-augmented pain. Nocebo hyperalgesia (i.e., increases in perceived pain resulting from negative expectations) has been found to impact how healthy and patient populations experience ...
Mia A. Thomaidou, Joseph S. Blythe, Simon J. Houtman, Dieuwke S. Veldhuijzen, Antoinette I. M. van Laarhoven, Andrea W. M. Evers   +5 more
doaj   +1 more source

Learning mechanisms in nocebo hyperalgesia: The role of conditioning and extinction processes

, 2021
Dataset by 'Learning mechanisms in nocebo hyperalgesia: The role of conditioning and extinction processes'
Thomaïdou, Mia
core   +2 more sources

Verbal modeling, counterconditioning, and operant conditioning are effective in nocebo hyperalgesia attenuation. [PDF]

Pain
Abstract Nocebo hyperalgesia, the increased pain following inert interventions, is frequently observed in clinical practice. This study investigates whether nocebo hyperalgesia can be reduced through counterconditioning, verbal modeling, and operant conditioning.
Rubanets D, Łaska I, Kłosowska J, Bąbel P, Bajcar EA.   +4 more
europepmc   +4 more sources

The role of pain expectancy and its confidence in placebo hypoalgesia and nocebo hyperalgesia. [PDF]

Pain
Abstract Placebo hypoalgesia and nocebo hyperalgesia, which exemplify the impact of expectations on pain, have recently been conceptualised as Bayesian inferential processes, yet empirical evidence remains limited. Here, we explore whether these phenomena can be unified within the same Bayesian framework by testing the predictive role of ...
Camerone EM, Tosi G, Romano D.
europepmc   +3 more sources

Placebo Effect on Pain-Related Autonomic Responses in a State of Experimentally-Induced Sensitization. [PDF]

Eur J Pain
ABSTRACT Background Pain‐related autonomic responses are increased after experimentally‐induced secondary mechanical hyperalgesia (SMH), as well as in a variety of chronic pain cohorts. In this state of sensitization, negative expectations further amplify these enhanced responses.
Allmendinger F, Utz O, Scheuren PS, Rosner J, Kramer JLK, Hubli M.   +5 more
europepmc   +2 more sources

Neural Correlates of Explicit Outcome Expectation Effects: An Activation Likelihood Estimation Meta-Analysis. [PDF]

Hum Brain Mapp
This ALE meta‐analysis of brain imaging studies published between 2014 and 2025 identified the caudate nucleus/lentiform nucleus as a core neural substrate of explicit outcome expectation effects, with the red nucleus emerging as an additional significant cluster.
Zhou J, Xu Y, Li T, Yang X.
europepmc   +2 more sources

Can Nocebo Effects Be Reduced via Open- and Closed-Label Counterconditioning? [PDF]

Eur J Pain
ABSTRACT Background The overwhelming evidence of nocebo effects adversely affecting the experience of physical symptoms, such as pain, puts emphasis on the study of possible strategies to reduce nocebo effects. Counterconditioning, during which a previously conditioned effect is reversed, has been shown to be a possible promising strategy in a previous
Meijer S, Evers AWM, Peerdeman KJ, van Middendorp H.   +3 more
europepmc   +2 more sources

Placebo or Nocebo Interventions as Affected by Hypnotic Susceptibility

Applied Sciences, 2023
The purpose of the present study was to examine placebo and nocebo effects under hypnotic analgesia in lowly hypnotizable (LH) and highly hypnotizable (HH) subjects.
Yair Sharav, Yaron Haviv, Michael Tal
doaj   +1 more source

Unraveling Inflammatory Pain: A Narrative Review of Molecular Pathways and Multidisciplinary Treatments. [PDF]

Health Sci Rep
ABSTRACT Background Inflammatory pain is a widespread global health concern arising from complex molecular pathways triggered by a consequence of tissue damage and immune activation. It significantly impacts quality of life and functional outcomes, necessitating a comprehensive understanding of underlying mechanisms and multidisciplinary approaches for
Elmansy FM, Elbqry MG, Al-Ahdal SA, Ashmieg FSO, Nasir PO, Abdullahi NM, Shalaby MN.   +6 more
europepmc   +2 more sources