Results 71 to 80 of about 9,513,177 (193)
Analgesia da placebo, anticipazione dolorifica e i possibili correlati neurali dell'effetto nocebo
The nocebo effect is a psychobiological effect that occurs when a negative psychosocial context that accompanies a therapy. Since the study of pain anticipation takes into account the temporal phase of the “expectation of hyperalgesia”, and considering ...
Sara Palermo
doaj +1 more source
Abstract This paper analyzes two disparate experiences of buprenorphine, a medication for opioid addiction, in California. Within the context of the U.S. War on Drugs and after decades of criminalization, buprenorphine represents a shift toward outpatient medical treatment of opioid addiction, but it has been unequally distributed and experienced ...
Lauren Textor
wiley +1 more source
Can a Brief Relaxation Exercise Modulate Placebo or Nocebo Effects in a Visceral Pain Model?
Translational research aiming to elucidate mediators and moderators of placebo and nocebo effects is highly relevant. This experimental study tested effects of a brief progressive muscle relaxation (PMR) exercise, designed to alter psychobiological ...
Sigrid Elsenbruch +3 more
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Contemporary psychiatric ethics emphasize autonomy and shared decision‐making, yet these frameworks may be strained in severe mental illnesses characterized by cognitive rigidity, fluctuating decisional capacity, and undue clinician influence. Severe and enduring anorexia nervosa serves as a case example to explore how therapeutic alliance, clinician ...
Elizabeth M. Olson +2 more
wiley +1 more source
Nocebo Responses in Brain Diseases: A Systematic Review of the Current Literature
Placebo is an intervention with no therapeutic effect that is used as a control in randomized controlled trials (RCTs). Placebo effects and responses can produce a beneficial effect that cannot be attributed to the properties of the intervention itself, since it is usually inactive, and should, therefore, be due to the patient's expectations about ...
Zis, Panagiotis +3 more
openaire +4 more sources
Classical Conditioning as a Distinct Mechanism of Placebo Effects
Classical conditioning was suggested as a mechanism of placebo effects in the 1950s. It was then challenged by response expectancy theory, which proposed that classical conditioning is just one of the means by which expectancies are acquired and changed.
Przemysław Bąbel
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Across 47 Phase 3 trials in Crohn's disease and ulcerative colitis, placebo exposure was associated with measurable harm. Disease exacerbation events showed the greatest excess risk, with one additional exacerbation occurring for every 8–13 patients assigned to placebo rather than active therapy.
Joëlle St‐Pierre +5 more
wiley +1 more source
Risk Assessment of Radio Frequencies and Public Information [PDF]
The rapid, worldwide development of mobile phones is accompanied in many countries by public concern over the possible health risks of radio frequencies (RF).
Marc Poumadère, Anne Perrin
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From preclinical promise to clinical translation in intervertebral disc degeneration (IDD). Robust preclinical evidence supports a range of biologic therapies, with consistent improvements in imaging, extracellular matrix composition, inflammation, and behavior.
Luca Ambrosio +5 more
wiley +1 more source
Conscious Expectation and Unconscious Conditioning in Analgesic, Motor, and Hormonal Placebo/Nocebo Responses [PDF]
The placebo and nocebo effect is believed to be mediated by both cognitive and conditioning mechanisms, although little is known about their role in different circumstances. In this study, we first analyzed the effects of opposing verbal suggestions on experimental ischemic arm pain in healthy volunteers and on motor performance in Parkinsonian ...
Fabrizio, Benedetti +5 more
openaire +2 more sources

