Results 31 to 40 of about 9,513,177 (193)
It is generally believed that the placebo response can elicit an analgesic effect, whilst the nocebo response can elicit a hyperalgesia effect in pain. Placebo analgesia and nocebo hyperalgesia effects are increasing concerns for researchers.
Yu Shi +7 more
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PO104 Placebo and nocebo responses in rls: a meta-analysis [PDF]
Objective Our goals were to estimate the placebo and nocebo responses in restless legs syndrome (RLS). Methods Databases were searched up to October 2015. Randomised, double-blind, placebo-controlled trials of RLS patient were included. ‘Placebo response’ was defined as the within-group change from baseline, using any scale measuring RLS severity or
Rodrigues, Filipe Brogueira +8 more
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Background: Nocebo effects, including nocebo hyperalgesia, are a common phenomenon in clinical routine with manifold negative consequences. Both explicit expectations and learning by conditioning are known to induce nocebo effects, but the specific role ...
Anne-Kathrin Bräscher +7 more
doaj +1 more source
Nocebo Responses to Antihypertensive Medications [PDF]
Apatient was seen in consultation for intolerance to multiple antihypertensive medications. She presented a list of her experiences, which is summarized in the Table. Although the cough she experienced while taking angiotensinconverting enzyme inhibitors was a typical side effect of this drug class and consistent on rechallenge, this was not the case ...
openaire +3 more sources
Temporal structure of brain oscillations predicts learned nocebo responses to pain [PDF]
AbstractThis study aimed to identify electrophysiological correlates of nocebo-augmented pain. Nocebo hyperalgesia (i.e., increases in perceived pain resulting from negative expectations) has been found to impact how healthy and patient populations experience pain and is a phenomenon that could be better understood in terms of its neurophysiological ...
Thomaïdou, A.M. +5 more
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Expectation modulates the effect of deep brain stimulation on motor and cognitive function in tremor-dominant Parkinson's disease. [PDF]
Expectation contributes to placebo and nocebo responses in Parkinson's disease (PD). While there is evidence for expectation-induced modulations of bradykinesia, little is known about the impact of expectation on resting tremor. Subthalamic nucleus (STN)
Ariane Keitel +4 more
doaj +1 more source
The Temporal Modulation of Nocebo Hyperalgesia in a Model of Sustained Pain
BackgroundThe direction and the magnitude of verbal suggestions have been shown to be strong modulators of nocebo hyperalgesia, while little attention has been given to the role of their temporal content. Here, we investigate whether temporal suggestions
Eleonora Maria Camerone +12 more
doaj +1 more source
DISCONTINUATION RATES FOLLOWING A SWITCH FROM A REFERENCE TO A BIOSIMILAR BIOLOGIC IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE: A SYSTEMATIC REVIEW AND META-ANALYSIS [PDF]
BACKGROUND: Biologics have revolutionized the treatment of inflammatory bowel disease (IBD). However, these drugs had a significant influence on treatment-related costs, which resulted in the development of biosimilars.
Natália Sousa Freitas QUEIROZ +6 more
doaj +1 more source
A Neural Mechanism for Nonconscious Activation of Conditioned Placebo and Nocebo Responses [PDF]
Fundamental aspects of human behavior operate outside of conscious awareness. Yet, theories of conditioned responses in humans, such as placebo and nocebo effects on pain, have a strong emphasis on conscious recognition of contextual cues that trigger the response.
Jensen, Karin B. +6 more
openaire +4 more sources
A placebo effect is a positive clinical response to non-specific elements of treatment with a sham or inert replica of a drug, device, or surgical intervention. There is considerable evidence that placebo effects are driven by expectation of benefit from
Hailey E. Yetman +6 more
doaj +1 more source

