Nocebo effects are stronger and more persistent than placebo effects in healthy individuals [PDF]
eLifePlacebo and nocebo effects illustrate the profound influence of cognitive-affective processes on symptom perception and treatment outcomes, with the potential to significantly alter responses to medical interventions.
Angelika Kunkel +6 more
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Counterconditioning as Treatment to Reduce Nocebo Effects in Persistent Physical Symptoms: Treatment Protocol and Study Design [PDF]
Frontiers in Psychology, 2022 Persistent physical symptoms have a high prevalence and a large impact for patients and society. To date, treatment effects for these symptoms are often limited.
Simone Meijer +9 more
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Risk factors associated with nocebo effects: A review of reviews [PDF]
Brain, Behavior, & Immunity - HealthObjective: This meta-review aims to identify and categorize the risk factors that are associated with nocebo effects. The nocebo effect can exert a negative impact on treatment outcomes and have detrimental outcomes on health.
Francesca Grosso +4 more
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Understanding and leveraging placebo and nocebo effects in perioperative care: a cross-sectional survey of German-speaking anesthesiologists [PDF]
BMC AnesthesiologyBackground Placebo and nocebo effects, beneficial or adverse responses shaped by patient expectations, modulate perioperative outcomes including pain, opioid requirement, recovery, and complication risk.
Johannes Wessels +7 more
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Nocebo Effects and Scratching Behaviour on Itch [PDF]
Acta Dermato-Venereologica, 2018 Nocebo effects, i.e. reduced treatment effects due to patients’ negative expectations, play a role in itch. Recent studies have shown that nocebo effects can be induced experimentally on itch and also be minimized and even turned into the opposite ...
Danielle J.P. Bartels +3 more
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Nocebo Effects on Cowhage-evoked Itch: A Randomized Controlled Trial of Classical Conditioning and Observational Learning [PDF]
Acta Dermato-Venereologica, 2021 To investigate learning processes underlying nocebo effects on itch, this study measured the efficacy of classical conditioning and observational learning for inducing nocebo effects on cowhage-evoked itch and scratching behaviour.
Joseph S. Blythe +6 more
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Nocebo effects in the treatment of endometriosis [PDF]
Reproduction and Fertility, 2021 The current approach to treating endometriosis is often inadequate or intolerable for many patients. Until more effective therapies are available, we should aim to maximize the effectiveness of our current options.
Peter Thiel +3 more
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The Other Side of the Coin: Nocebo Effects and Psychotherapy [PDF]
Frontiers in Psychiatry, 2019 Psychotherapy and placebo have a long history, and both have been shown to have significant and clinically meaningful effects. In the last 100 years and up to today, psychotherapy has been subject to an enduring and often heated debate about its ...
Cosima Locher +5 more
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Learning by observing: a systematic exploration of modulatory factors and the impact of observationally induced placebo and nocebo effects on treatment outcomes [PDF]
Frontiers in PsychologyIntroductionObservational learning (OL) refers to learning through observing other people’s behavior. OL has been suggested as an effective and simple tool to evoke treatment expectations and corresponding placebo and nocebo effects.
Helena Klauß +4 more
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The Clinical Implications of Nocebo Effects for Biosimilar Therapy [PDF]
Frontiers in Pharmacology, 2019 Nocebo effects encompass negative responses to inert interventions in the research setting and negative outcomes with active treatments in the clinical research or practice settings, including new or worsening symptoms and adverse events, stemming from ...
Luana Colloca +3 more
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