Reviewing the Severity of Handling‐Induced Injuries in the LAKSVEL Protocol for Salmon Welfare
ABSTRACT Injuries from lice treatments are ranked as a major cause of mortality and poor welfare for Atlantic salmon in marine net pens. As a result, scoring schemes based on the external appearance of injuries and severity are now frequently used.
Lars Helge Stien+9 more
wiley +1 more source
Decoding Pain: Next‐Generation In Vitro Systems for Mechanistic Insights and Drug Discovery
Developing an in vitro pain model that mimics essential features of the in vivo pain circuit requires careful consideration of multiple components and choices. These include selecting the cellular population for the model, choosing from the origin of nociceptors and other cells that are cultured, deciding between 3D or 2D dimensions, designing the ...
Dara Khosrowshahi+2 more
wiley +1 more source
Corneal Sensory Receptors and Pharmacological Therapies to Modulate Ocular Pain. [PDF]
Park R+14 more
europepmc +1 more source
Terminal organization of C-fiber afferents related with nociception or non-nociception
Yasuo Sugiura
openalex +2 more sources
Nociception is the root cause of postoperative nausea and vomiting: hypothesis [PDF]
S. Rao Mallampati
openalex +1 more source
Presbycusis: Pathology, Signal Pathways, and Therapeutic Strategy
In ARHL, the stria vascularis, acting as a cochlear battery, gradually loses its ability to maintain the endocochlear potential, leading to impaired hair cell function and progressive hearing loss. Single‐cell sequencing reveals age‐related cellular changes in the cochlea, providing insights into the underlying mechanisms of aging and potential ...
Xiaoxu Zhao+12 more
wiley +1 more source
Facial expressions during compound interventions of nociception, conspecific isolation, and sedation in horses. [PDF]
Lundblad J+5 more
europepmc +1 more source
Trypsin mediates nociception via the proteinase-activated receptor 2: A potentially novel role in pancreatic pain [PDF]
Willemijntje A. Hoogerwerf+5 more
openalex +1 more source
Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine
Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang+4 more
wiley +1 more source
Nano‐Anesthetics Regulate Neuro‐Immune Interaction for Treating Neuropathic Pain
Ce‐UiO‐66‐Bupivacaine (CUB) demonstrates triple therapeutic innovation: 1) Sustained analgesia with ROS scavenging synergistically resolves neuropathic pain; 2) Microglia/astrocyte polarization switch reprograms the pro‐regenerative immune microenvironment; 3) CGRP‐TSP‐1 axis activation couples inflammation suppression to axon regeneration, defining a ...
Yue Wang+9 more
wiley +1 more source