Results 231 to 240 of about 87,919 (361)

Stabilized Ion Selectivity Corrects Activation Drift in Kalium Channelrhodopsins

open access: yesAdvanced Science, Volume 13, Issue 6, 30 January 2026.
As newly emerged optogenetic tools, potassium channelrhodopsins (KCRs) can drift from inhibition to activation during illumination as K⁺ selectivity declines. It is shown that both the absolute K⁺/Na⁺ permeability ratio and its stability over time govern this drift, identify KCR1‐C29D as a reliably inhibitory variant, and outline design principles for ...
Xiao Duan   +14 more
wiley   +1 more source

Orofacial antinociceptive effect of a novel 2-amino-thiophene derivative and its possible targets of action. [PDF]

open access: yesBraz Oral Res
Silva AJD   +10 more
europepmc   +1 more source

Acute inflammation reveals GABAAreceptor-mediated nociception in mouse dorsal root ganglion neurons via PGE2receptor 4 signaling [PDF]

open access: gold, 2017
In Jeong Jang   +9 more
openalex   +1 more source

Induced Proprioceptor and Low‐Threshold Mechanoreceptor Neurons Derived from Human Pluripotent Stem Cells Exhibit Distinct Functional Mechanosensory Properties

open access: yesAdvanced Science, Volume 13, Issue 6, 30 January 2026.
This study describes derivation of two distinct mechanosensory subpopulations from human pluripotent stem cells using a transcription factor mediated approach. Of significance, functional interrogation of induced mechanosensory subtypes reveal their unique responses to mechanical stimulation in the absence of end‐organs.
Amy J. Hulme   +12 more
wiley   +1 more source

Spreading depolarization activates the cGAS-STING pathway and drives cranial nociception: therapeutic potential of STING modulation. [PDF]

open access: yesJ Headache Pain
Soylu KO   +7 more
europepmc   +1 more source

Effects of COX‐2 inhibition on spinal nociception: the role of endocannabinoids [PDF]

open access: bronze, 2010
LE Staniaszek   +4 more
openalex   +1 more source

Home - About - Disclaimer - Privacy