Threshold and rate sensitivity of low‐threshold thermal nociception
Barry G. Green, Carol Akirav
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Voltage-sensitive calcium channels in spinal nociceptive processing: blockade of N- and P-type channels inhibits formalin-induced nociception [PDF]
AB Malmberg, TL Yaksh
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Stabilized Ion Selectivity Corrects Activation Drift in Kalium Channelrhodopsins
As newly emerged optogenetic tools, potassium channelrhodopsins (KCRs) can drift from inhibition to activation during illumination as K⁺ selectivity declines. It is shown that both the absolute K⁺/Na⁺ permeability ratio and its stability over time govern this drift, identify KCR1‐C29D as a reliably inhibitory variant, and outline design principles for ...
Xiao Duan +14 more
wiley +1 more source
Orofacial antinociceptive effect of a novel 2-amino-thiophene derivative and its possible targets of action. [PDF]
Silva AJD +10 more
europepmc +1 more source
Acute inflammation reveals GABAAreceptor-mediated nociception in mouse dorsal root ganglion neurons via PGE2receptor 4 signaling [PDF]
In Jeong Jang +9 more
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This study describes derivation of two distinct mechanosensory subpopulations from human pluripotent stem cells using a transcription factor mediated approach. Of significance, functional interrogation of induced mechanosensory subtypes reveal their unique responses to mechanical stimulation in the absence of end‐organs.
Amy J. Hulme +12 more
wiley +1 more source
Spreading depolarization activates the cGAS-STING pathway and drives cranial nociception: therapeutic potential of STING modulation. [PDF]
Soylu KO +7 more
europepmc +1 more source
Effects of COX‐2 inhibition on spinal nociception: the role of endocannabinoids [PDF]
LE Staniaszek +4 more
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