Results 231 to 240 of about 70,074 (346)

Reviewing the Severity of Handling‐Induced Injuries in the LAKSVEL Protocol for Salmon Welfare

open access: yesReviews in Aquaculture, Volume 17, Issue 4, September 2025.
ABSTRACT Injuries from lice treatments are ranked as a major cause of mortality and poor welfare for Atlantic salmon in marine net pens. As a result, scoring schemes based on the external appearance of injuries and severity are now frequently used.
Lars Helge Stien   +9 more
wiley   +1 more source

Decoding Pain: Next‐Generation In Vitro Systems for Mechanistic Insights and Drug Discovery

open access: yesThe FASEB Journal, Volume 39, Issue 16, 31 August 2025.
Developing an in vitro pain model that mimics essential features of the in vivo pain circuit requires careful consideration of multiple components and choices. These include selecting the cellular population for the model, choosing from the origin of nociceptors and other cells that are cultured, deciding between 3D or 2D dimensions, designing the ...
Dara Khosrowshahi   +2 more
wiley   +1 more source

Corneal Sensory Receptors and Pharmacological Therapies to Modulate Ocular Pain. [PDF]

open access: yesInt J Mol Sci
Park R   +14 more
europepmc   +1 more source

Presbycusis: Pathology, Signal Pathways, and Therapeutic Strategy

open access: yesAdvanced Science, Volume 12, Issue 29, August 7, 2025.
In ARHL, the stria vascularis, acting as a cochlear battery, gradually loses its ability to maintain the endocochlear potential, leading to impaired hair cell function and progressive hearing loss. Single‐cell sequencing reveals age‐related cellular changes in the cochlea, providing insights into the underlying mechanisms of aging and potential ...
Xiaoxu Zhao   +12 more
wiley   +1 more source

Facial expressions during compound interventions of nociception, conspecific isolation, and sedation in horses. [PDF]

open access: yesSci Rep
Lundblad J   +5 more
europepmc   +1 more source

Trypsin mediates nociception via the proteinase-activated receptor 2: A potentially novel role in pancreatic pain [PDF]

open access: bronze, 2004
Willemijntje A. Hoogerwerf   +5 more
openalex   +1 more source

Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine

open access: yesAdvanced Science, Volume 12, Issue 29, August 7, 2025.
Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang   +4 more
wiley   +1 more source

Nano‐Anesthetics Regulate Neuro‐Immune Interaction for Treating Neuropathic Pain

open access: yesAdvanced Science, Volume 12, Issue 29, August 7, 2025.
Ce‐UiO‐66‐Bupivacaine (CUB) demonstrates triple therapeutic innovation: 1) Sustained analgesia with ROS scavenging synergistically resolves neuropathic pain; 2) Microglia/astrocyte polarization switch reprograms the pro‐regenerative immune microenvironment; 3) CGRP‐TSP‐1 axis activation couples inflammation suppression to axon regeneration, defining a ...
Yue Wang   +9 more
wiley   +1 more source

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