Results 251 to 260 of about 85,874 (280)
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Current Drug Target -CNS & Neurological Disorders, 2004
Noxious thermal, mechanical, or chemical stimuli evoke pain through excitation of the peripheral terminals called nociceptor, and many kinds of ionotropic and metabotropic receptors are involved in this process. Capsaicin receptor TRPV1 is a nociceptor-specific ion channel that serves as the molecular target of capsaicin.
Mitsuko, Numazaki, Makoto, Tominaga
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Noxious thermal, mechanical, or chemical stimuli evoke pain through excitation of the peripheral terminals called nociceptor, and many kinds of ionotropic and metabotropic receptors are involved in this process. Capsaicin receptor TRPV1 is a nociceptor-specific ion channel that serves as the molecular target of capsaicin.
Mitsuko, Numazaki, Makoto, Tominaga
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Intraoperative Nociception Monitoring
Anesthesiology Clinics, 2021Nociception refers to the process of encoding and processing noxious stimuli. Its monitoring can have potential benefits. Under anesthesia, nociceptive signals are continuously generated to cause involuntary effects on the autonomic nervous system, reflex movement, and stress response. Most available systems depend on the identification and measurement
Girish P. Joshi +2 more
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Minerva Anestesiologica, 2019
INTRODUCTION Under-dosage or over-dosage of intraoperative analgesia can cause harm to patients. Many studies have demonstrated the clinical advantages of nociception monitoring tools, but with some conflicting results.
Yang Jiao +5 more
semanticscholar +1 more source
INTRODUCTION Under-dosage or over-dosage of intraoperative analgesia can cause harm to patients. Many studies have demonstrated the clinical advantages of nociception monitoring tools, but with some conflicting results.
Yang Jiao +5 more
semanticscholar +1 more source
Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 1985
There is evidence that the cerebral cortex is involved in the perception of pain but no specific area appears to be the ‘pain centre’. Limited knowledge exists on the cortical processing of the noxious input. The nociceptors are most likely to activate at least two different systems with different characteristics.
S. A. Andersson, B. Rydenhag
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There is evidence that the cerebral cortex is involved in the perception of pain but no specific area appears to be the ‘pain centre’. Limited knowledge exists on the cortical processing of the noxious input. The nociceptors are most likely to activate at least two different systems with different characteristics.
S. A. Andersson, B. Rydenhag
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Prostanoids in nociception and pain
Biochemical Pharmacology, 2007Prostaglandins are lipid mediators produced by cyclooxygenases from arachidonic acid, which serve pivotal functions in inflammation and pain. Inhibition of their production is the major analgesic mechanism of action of non-steroidal anti-inflammatory drugs (NSAIDs)-but also the source of most of their unwanted effects.
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Nociceptive pathways: anatomy and physiology of nociceptive ascending pathways
Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 1985In primates, the principal nociceptive pathways ascend in the anterolateral quadrant of the spinal cord. Among these, the spinothalamic tract (s.t.t.) is the best studied. Cells in Rexed’s laminae I and V project to the ventro-posterolateral (v.p.l.) thalamic nucleus.
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Nociceptive and Non-nociceptive Hypersensitivity at Latent Myofascial Trigger Points
The Clinical Journal of Pain, 2009The aim of the study was to evaluate whether or not there exists nociceptive and non-nociceptive hypersensitivity at latent myofascial trigger points (MTrPs).Eleven healthy volunteers participated in this study, which consisted of 3 sessions of electromyography-guided intramuscular injection with a minimum of a week interval in between. In each session,
Li, Lian-Tao +3 more
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1996
By far the majority of studies with cytokines relate to neuroendocrine functions, fever and sleep.1 Recently, however, the possibility of a role for cytokines in nociception has been explored. In particular the work of Watkins et al2,3 have studied central and peripheral involvement of IL-1β in nociception in depth.
A. J. Davis, M. N. Perkins
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By far the majority of studies with cytokines relate to neuroendocrine functions, fever and sleep.1 Recently, however, the possibility of a role for cytokines in nociception has been explored. In particular the work of Watkins et al2,3 have studied central and peripheral involvement of IL-1β in nociception in depth.
A. J. Davis, M. N. Perkins
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Minerva Anestesiologica, 2018
BACKGROUND The NOL index is based on multiparametric analysis of heart rate (HR), skin conductance, wave plethysmography, and their time derivative. The aim of this study was to evaluate the NOL to detect standardized nociceptive stimuli with various ...
Pierre-André Stöckle +12 more
semanticscholar +1 more source
BACKGROUND The NOL index is based on multiparametric analysis of heart rate (HR), skin conductance, wave plethysmography, and their time derivative. The aim of this study was to evaluate the NOL to detect standardized nociceptive stimuli with various ...
Pierre-André Stöckle +12 more
semanticscholar +1 more source
2013
Pain is a fundamental self-defense mechanism for warning against damage so that action can be taken to avoid or minimize injury. According to the International Association for the Study of Pain (IASP) pain is defined as “An unpleasant sensory and emotional experience associated with actual or potential tissue damage or described in terms of such damage”
Angelo Reggiani, Maria P. Abbracchio
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Pain is a fundamental self-defense mechanism for warning against damage so that action can be taken to avoid or minimize injury. According to the International Association for the Study of Pain (IASP) pain is defined as “An unpleasant sensory and emotional experience associated with actual or potential tissue damage or described in terms of such damage”
Angelo Reggiani, Maria P. Abbracchio
openaire +2 more sources