Results 191 to 200 of about 40,810 (316)

Mitogen- and stress-activated kinase 1 in primary sensory neurons contributes to formalin-induced tonic pain. [PDF]

open access: yesPain Rep
Irfan J   +11 more
europepmc   +1 more source

CGRP‐Loaded ROS‐Responsive Hydrogel Restores Neuro‐Angiogenic Signaling to Promote Bone Regeneration in Diabetes‐Associated Periodontitis

open access: yesAdvanced Science, Volume 12, Issue 40, October 27, 2025.
This study shows that diabetes damages sensory nerve fibers, especially CGRP‐positive ones, in the periodontium and disrupts autophagy in trigeminal ganglion neurons, affecting bone homeostasis by inhibiting type H vessel formation. To address this, CGRP@PVA/tsPBA hydrogels are developed to release CGRP in response to ROS, which binds to endothelial ...
Chaoning Zhan   +7 more
wiley   +1 more source

Type I IFNs enhance human dorsal root ganglion nociceptor excitability and induce TRPV1 sensitization. [PDF]

open access: yesJCI Insight
Franco-Enzástiga Ú   +5 more
europepmc   +1 more source

μ‐Opioid Receptor Dynamics in the Parameningeal Tissue During Migraine Attacks

open access: yesAnnals of Neurology, Volume 98, Issue 4, Page 777-787, October 2025.
Objective The possible impact of meningeal μ‐opioid receptor (μOR) binding in migraine remains unknown. This study investigated μOR availability in the cranial parameninges involved in migraine initiation via nociceptor activation. Methods We used positron emission tomography with [11C] carfentanil, and measured μOR availability in meninges and ...
Dajung J. Kim   +6 more
wiley   +1 more source

Association Between Interictal Sensory Hypersensitivities and Vestibular Symptoms in Migraine: A Cross‐Sectional Study

open access: yesBrain and Behavior, Volume 15, Issue 10, October 2025.
This cross‐sectional study of 274 migraine patients examined the association between interictal hypersensitivities (photophobia, phonophobia, and osmophobia) and vestibular symptoms. Vestibular symptoms were significantly more frequent in patients with interictal hypersensitivities, and risk increased with the number of modalities affected.
Alex Jaimes   +4 more
wiley   +1 more source

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