Results 291 to 300 of about 40,810 (316)
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Sympathetic Activation of A-Delta Nociceptors
Somatosensory Research, 1985Primary afferent units in the saphenous nerve of cats, functionally identified as A-delta myelinated nociceptors, were tested for their responses to stimulation of the sympathetic trunk. The units were subdivided functionally into A-mechano-heat receptors (AMHs), which respond to both noxious heat and pressure, and high-threshold mechanoreceptors (HTMs)
S. M. Elardo, W. J. Roberts
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Effects of Bradykinin on Nociceptors
2009Abstract Bradykinin is a potent mediator formed upon tissue damage and inflammation. It can both excite and sensitize nociceptors to heat, mechanical, and chemical stimuli. Two types of bradykinin receptors (B1 and B2) have been identified of which the constitutive B2 receptors mediate most of the acute effects of bradykinin in uninflamed tissues ...
Gábor Pethő, Peter W. Reeh
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Chloride Channels in Nociceptors
2019Abstract Pain may be induced by activation of various ion channels expressed in primary afferent neurons. These channels function as molecular sensors that detect noxious chemical, temperature, or tactile stimuli and transduce them into nociceptor electrical signals.
Uhtaek Oh, Jooyoung Jung
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The changing sensitivity in the life of the nociceptor
Pain, 1999Plasticity of the central nervous system has been shown to be an important correlate in the generation of chronic pain. However, there is now also increasing evidence for profound changes of the primary sensory neurons including nociceptors throughout the life of an organism and these changes account for clinically relevant alterations of pain ...
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Cutaneous Mechanoreceptors and Nociceptors
1973Although information from sense organs is used by all animals, only man can verbally report his sensory experience. A brief consideration of these experiences may be useful in providing insight into cutaneous sensory mechanisms. Nonnoxious deformation of the human skin with a stimulator having a small surface area (2–3 mm2) evokes sensations usually ...
Paul R. Burgess, Edward R. Perl
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