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American family physician, 2012
Up to 60 percent of adults report that they have had nocturnal leg cramps. The recurrent, painful tightening usually occurs in the calf muscles and can cause severe insomnia. The exact mechanism is unknown, but the cramps are probably caused by muscle fatigue and nerve dysfunction rather than electrolyte or other abnormalities. Nocturnal leg cramps are
Richard E, Allen, Karl A, Kirby
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Up to 60 percent of adults report that they have had nocturnal leg cramps. The recurrent, painful tightening usually occurs in the calf muscles and can cause severe insomnia. The exact mechanism is unknown, but the cramps are probably caused by muscle fatigue and nerve dysfunction rather than electrolyte or other abnormalities. Nocturnal leg cramps are
Richard E, Allen, Karl A, Kirby
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Are There Alternatives to the Use of Quinine to Treat Nocturnal Leg Cramps?
The Consultant Pharmacist, 2008To review the efficacy and tolerability profiles of quinine in nocturnal and dialysis-associated leg cramps and to examine potential alternative agents.Selection and extraction: a MEDLINE/PubMed, English-language literature search from 1966 to the present using quinine, leg cramps, vitamin E, verapamil, muscle relaxants, gabapentin as search terms ...
Guay David
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Spine, 2009
Questionnaire survey on leg cramps for patients with lumbar spinal canal stenosis (LCS).To evaluate the prevalence of leg cramps in patients with LCS treated surgically and the relationship between leg cramps and the surgical outcomes.Although it has been anecdotally reported that LCS patients have suffered from leg cramps, the true prevalence remains ...
Morio, Matsumoto +9 more
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Questionnaire survey on leg cramps for patients with lumbar spinal canal stenosis (LCS).To evaluate the prevalence of leg cramps in patients with LCS treated surgically and the relationship between leg cramps and the surgical outcomes.Although it has been anecdotally reported that LCS patients have suffered from leg cramps, the true prevalence remains ...
Morio, Matsumoto +9 more
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JAMA: The Journal of the American Medical Association, 1980
NOCTURNAL leg muscle cramping (NLMC) is a frequent complaint heard by physicians in all specialties, from patients of all age groups, though probably most commonly in the elderly. Such muscle cramping usually involves the calf muscles (gastrocnemius or soleus) or the small intrinsic muscles of the sole of the foot.
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NOCTURNAL leg muscle cramping (NLMC) is a frequent complaint heard by physicians in all specialties, from patients of all age groups, though probably most commonly in the elderly. Such muscle cramping usually involves the calf muscles (gastrocnemius or soleus) or the small intrinsic muscles of the sole of the foot.
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Treatment of Nocturnal Leg Cramps
Archives of Internal Medicine, 1992Objective.— This study compared the efficacy and safety of quinine sulfate, vitamin E, and placebo in the treatment of nocturnal leg cramps. Design.— A random-order, double-blind, placebocontrolled crossover trial was performed. Setting.— The study was conducted at the Veterans Affairs Medical Center, White River Junction, Vt.
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Treatment of Nocturnal Leg Cramps-Reply
Archives of Internal Medicine, 1994We thank Brunetti and colleagues for their comments. They make some interesting points about the potential biases inherent in crossover trials, but we do not feel that they invalidate the conclusions of our study showing the effectiveness of quinine as a treatment for nocturnal leg cramps. The initial "run-in" period was to ensure some measurable cramp
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[Nocturnal leg cramps--their causes and treatment].
Medizinische Klinik, 1980Organic causes for nocturnal or recumbency leg cramps as venous, arterial, statical, nervous, rheumatical and metabolic diseases such as tetany, diabetes and gout must be excluded. This means also electrolyte disturbances during a medical treatment, for example with diuretics. In addition there is a very high portion of idiopathic cramps.
H, Mörl, H A, Dieterich
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