Results 181 to 190 of about 19,932 (234)

Aggressive periodontitis and NOD2 variants

Journal of Human Genetics, 2020
Aggressive periodontitis (AgP) occurs at an early age and causes rapid periodontal tissue destruction. Nucleotide-binding oligomerization domain-containing protein 2 (NOD2) encodes a protein with two caspase recruitment domains and eleven leucine-rich repeats.
Noriyoshi Mizuno, Kodai Kume, Yukiko Nagatani, Shinji Matsuda, Tomoyuki Iwata, Kazuhisa Ouhara, Mikihito Kajiya, Katsuhiro Takeda, Yukiko Matsuda, Yui Tada, Ryosuke Ohsawa, Hiroyuki Morino, Keichiro Mihara, Tsuyoshi Fujita, Hiroyuki Kawaguchi, Hideki Shiba, Hideshi Kawakami, Hidemi Kurihara   +17 more
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Freund's adjuvant, NOD2 and mycobacteria

Current Opinion in Microbiology, 2015
Mycobacterium tuberculosis contributed to the discovery of delayed-type hypersensitivity and cell-mediated immunity. However, the biochemical basis for the immunogenicity of the mycobacterial cell wall has until recently remained unknown.Nucleotide-binding oligomerization domain-containing protein 2 (NOD2) responds to bacterial peptidolycan-derived ...
Marcel A, Behr, Maziar, Divangahi
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NOD2 and Mycobacteria

2010
The genus Mycobacterium comprises a variety of highly successful intracellular pathogens. Mycobacterium tuberculosis is the causative agent of tuberculosis (TB) in humans and currently infects one third of the world's population. Mycobacterium avium ssp.
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Nod2, Not Yet.

Inflammatory Bowel Diseases, 2005
Steven R, Brant, Dermot P B, McGovern
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The biology of Nod2

2006
The NOD-LRR (nucleotide-binding oligomerization domain, leucine-rich repeat) family of proteins in mammals form part of a wider, extremely well conserved pathogen detection system that includes the CED (cell death abnormality) proteins in C. elegans and the pathogen-detecting disease resistance (R) proteins in plants. The mammalian NOD-LRR protein Nod2
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