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Nucleotide-binding oligomerization domain 2 (NOD2) is a cytoplasmic pattern recognition receptor (PRR), which is involved in innate antibacterial and antiviral responses.
Ming Xian Chang, Tiehui Wang, Pin Nie
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Aggressive periodontitis and NOD2 variants
Journal of Human Genetics, 2020Aggressive periodontitis (AgP) occurs at an early age and causes rapid periodontal tissue destruction. Nucleotide-binding oligomerization domain-containing protein 2 (NOD2) encodes a protein with two caspase recruitment domains and eleven leucine-rich repeats.
Noriyoshi Mizuno +17 more
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Freund's adjuvant, NOD2 and mycobacteria
Current Opinion in Microbiology, 2015Mycobacterium tuberculosis contributed to the discovery of delayed-type hypersensitivity and cell-mediated immunity. However, the biochemical basis for the immunogenicity of the mycobacterial cell wall has until recently remained unknown.Nucleotide-binding oligomerization domain-containing protein 2 (NOD2) responds to bacterial peptidolycan-derived ...
Marcel A, Behr, Maziar, Divangahi
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