Results 51 to 60 of about 16,568 (299)

Tumor‐Derived Exosomes Deliver Membrane‐Bound Fgl2 to Activate FcγRIIB‐Mediated Immunosuppression in Myeloid‐Derived Suppressor Cells

Advanced Science, EarlyView.
This study reveals that the Fgl2‐FcγRIIB signaling axis is a key mechanism by which MDSCs mediate tumor immune evasion. Tumor‐derived exosomes systemically activate MDSCs via this pathway, positioning this axis as a promising broad‐spectrum target for cancer immunotherapy.
Fenglin Lin, Dingqin Cai, Chunli Jian, Yaxian Qi, Linpeng Zheng, Qiao Yang, Longyao Zhang, Diangang Chen, Lingchen Li, Ping Cai, Lingyou Sun, Luping Zhang, Jianguo Sun   +12 more
wiley   +1 more source

Disrupted Topological Organization in White Matter Networks in Unilateral Sudden Sensorineural Hearing Loss

Frontiers in Neuroscience, 2021
Sudden sensorineural hearing loss (SSNHL) is a sudden-onset hearing impairment that rapidly develops within 72 h and is mostly unilateral. Only a few patients can be identified with a defined cause by routine clinical examinations. Recently, some studies
Yan Zou, Yan Zou, Hui Ma, Hui Ma, Bo Liu, Dan Li, Dingxi Liu, Dingxi Liu, Xinrong Wang, Siqi Wang, Siqi Wang, Wenliang Fan, Wenliang Fan, Ping Han, Ping Han   +14 more
doaj   +1 more source

Nodal morphogens

, 2009
Nodal signals belong to the TGF-beta superfamily and are essential for the induction of mesoderm and endoderm and the determination of the left-right axis.
Schier, Alexander F.
core   +1 more source

Targeting Supramolecular Active Complexes of Nav1.7/Nav1.8 to Relieve Chronic Neuropathic Pain

Advanced Science, EarlyView.
In mice and patients with severe chronic neuropathic pain (NP), Nav1.7, Nav1.8, TrkB, and five cytoskeletal proteins form supramolecular active complexes (SMACs) with polygonal lattice structures as noxious signal amplifiers in dorsal root ganglion (DRG) neurons.
Liting Sun, Hang Xian, Yunxin Shi, Taotan Yang, Hongyan Shuai, Wenchao Hu, Siying Fei, Miao Xu, Taoyuan Yang, Ruilong Xia, Ting Wen, Fengting Zhu, Yan Fu, Yang Li, Wei Xia, Ran Qian, Yuanying Liu, Zhicheng Tian, Lamei Li, Qian Zhou, Lize Xiong, Rui Cong, Ceng Luo, Shengxi Wu, Xiafeng Shen, Xin Yu, Rou‐Gang Xie, Changgeng Peng   +27 more
wiley   +1 more source

Resolution of the Generalized Eigenvalue Problem in the Neutron Diffusion Equation Discretized by the Finite Volume Method

Abstract and Applied Analysis, 2014
Numerical methods are usually required to solve the neutron diffusion equation applied to nuclear reactors due to its heterogeneous nature. The most popular numerical techniques are the Finite Difference Method (FDM), the Coarse Mesh Finite Difference ...
Álvaro Bernal, Rafael Miró, Damián Ginestar, Gumersindo Verdú   +3 more
doaj   +1 more source

Dumbbell‐Structured Plasmonic‐Enhanced Optical Nanoprobes Boosting Photo‐Magnetic‐Acoustic Multimodal Imaging‐Guided Photodynamic‐Photothermal Synergistic Treatment and Immunogenic Death in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
This study reports a novel rationally‐designed optical nanoprobe based on dumbbell‐shaped mesoporous silica‐coated gold nanorods, loaded with rare‐earth oxides, photosensitizers, and tumor‐targeted peptides, enabling plasmonic‐enhanced multimodal imaging and PTT‐PDT synergy.
Baikang Zhuang, Yubiao Yang, Wen Han, Yi Tang, Chengxin Yao, Fuli Zhao, Wenxiao Fang, Jinjie Li, Xiaolan Huo, Yiqian An, Yuanzhi Shao, Botao Gao, Jinchang Yin   +12 more
wiley   +1 more source

2D Inorganic Electrides: Interstitial Electrons as Key Drivers of Multifunctional Properties and Applications

Advanced Science, EarlyView.
Eight AB‐type 2D inorganic electrides with negatively charged transition metals are theoretically designed. Their monolayers exhibit intrinsic magnetic ordering, rich topological phases, and ultralow work functions. Supported metal Ru on these 2D inorganic electrides effectively alleviates hydrogen poisoning and enables efficient ammonia synthesis ...
Qianwen Zhang, Xia Cheng, Zhenzhou Guo, Weiyao Jia, Ying Yang, Zhenxiang Cheng, Weizhen Meng   +6 more
wiley   +1 more source

Alterations of White Matter Network Properties in Patients With Functional Constipation

Frontiers in Neurology, 2021
Background: The abnormalities in brain function and structure of patients with functional constipation (FC) have been identified using multiple neuroimaging studies and have confirmed the abnormal processing of visceral sensation at the level of the ...
Ma Peihong, Ma Peihong, Yin Tao, Yin Tao, He Zhaoxuan, He Zhaoxuan, Yang Sha, Yang Sha, Chen Li, Chen Li, Xie Kunnan, Xie Kunnan, Chen Jingwen, Chen Jingwen, Hou Likai, Hou Likai, Teng Yuke, Teng Yuke, Guo Yuyi, Guo Yuyi, Wang Fumin, Wang Fumin, Tian Zilei, Tian Zilei, Sun Ruirui, Sun Ruirui, Zeng Fang, Zeng Fang   +27 more
doaj   +1 more source

Analytic Basis Function Expansion Nodal Method for Neutron Diffusion Equations in Triangular Geometry

, 2010
An analytic basis function expansion nodal method for directly solving the two-group neutron diffusion equation in the triangular geometry is proposed in the present paper. In this method, the distribution of neutron flux is expanded by a set of analytic
Kunpeng Wang, Liangzhi Cao, Changhui Wang, Hongchun Wu   +3 more
core   +1 more source

Topological Materials and Related Applications

Advanced Electronic Materials, EarlyView.
This review covers topological materials—including topological insulators, quantum valley Hall and quantum spin Hall insulators, and topological Weyl and Dirac semimetals—as well as their most recent advancements in fields such as spintronics, electronics, photonics, thermoelectrics, and catalysis.
Carlo Grazianetti, Roberto Mantovan, Emanuele Longo, Harold J. W. Zandvliet, Pantelis Bampoulis, Yu Pan, Fan Li, Xia Wang, Payton Downey, Alessandro Molle   +9 more
wiley   +1 more source