Results 51 to 60 of about 627,745 (234)

Construction of China’s automobile financial market network and its sustainability evaluation

open access: yesFrontiers in Environmental Science, 2022
“Made in China” has spread all over the world, and China has the status of “world factory”. However, the weak ability of independent innovation has affected the sustainable development of China’s manufacturing industry.
Hongzhen Liang   +2 more
doaj   +1 more source

Dynamic importance sampling for queueing networks

open access: yes, 2007
Importance sampling is a technique that is commonly used to speed up Monte Carlo simulation of rare events. However, little is known regarding the design of efficient importance sampling algorithms in the context of queueing networks.
Dupuis, Paul   +2 more
core   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Multimodal Brain Network Jointly Construction and Fusion for Diagnosis of Epilepsy

open access: yesFrontiers in Neuroscience, 2021
Brain network analysis has been proved to be one of the most effective methods in brain disease diagnosis. In order to construct discriminative brain networks and improve the performance of disease diagnosis, many machine learning–based methods have been
Qi Zhu   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Attributed Network Embedding for Learning in a Dynamic Environment

open access: yes, 2018
Network embedding leverages the node proximity manifested to learn a low-dimensional node vector representation for each node in the network. The learned embeddings could advance various learning tasks such as node classification, network clustering, and
Chang, Yi   +5 more
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Roadmap Modeling and Assessment Approach for Defense Technology System of Systems

open access: yesApplied Sciences, 2018
Advanced defense technology plays a crucial role in safeguarding national safety and development interests. Aiming to handle the problems of current research and development (R&D) management approaches faced with the rocketing complexities of system ...
Hui Lu, Hanlin You
doaj   +1 more source

Spin and pseudospin symmetries of the Dirac equation with confining central potentials

open access: yes, 2013
We derive the node structure of the radial functions which are solutions of the Dirac equation with scalar $S$ and vector $V$ confining central potentials, in the conditions of exact spin or pseudospin symmetry, i.e., when one has $V=\pm S+C$, where $C ...
Alberto, P.   +2 more
core   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

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