Results 41 to 50 of about 2,301,764 (289)

Tumor-draining lymph nodes are pivotal in PD-1/PD-L1 checkpoint therapy.

open access: yesJCI Insight, 2018
PD-1/PD-L1 checkpoint therapy for cancer is commonly considered to act by reactivating T cells in the tumor microenvironment. Here, we present data from 2 mouse tumor models demonstrating an essential involvement of tumor-draining lymph nodes in PD-1 and
M. Fransen   +7 more
semanticscholar   +1 more source

Carcinomas and Carcinoid Tumors of the Lungs and Bronchi in Children and Adolescents: The EXPeRT Recommendations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Primary lung carcinomas and bronchial carcinoid tumors (BC) are very rare malignancies in childhood. While typical BC and mucoepidermoid carcinomas are mostly low‐grade, localized tumors with a more favorable prognosis than in adults, necessitating avoidance of overtreatment, adenocarcinomas of the lung are often diagnosed at advanced disease ...
Michael Abele   +19 more
wiley   +1 more source

Reconstructing the Antikythera Mechanism lost eclipse events applying the Draconic gearing - the impact of gear error [PDF]

open access: yesCultural Heritage and Modern Technologies
We present new observations concerning the procedure for the reconstruction of the lost eclipse events engraved in the Saros spiral cells of the Antikythera Mechanism.
Aristeidis Voulgaris   +2 more
doaj   +1 more source

Diversification of Galianthe species (Rubiaceae) in the Neotropical seasonally dry forests: a case study of a mainly subshrubby genus [PDF]

open access: yesPlant Ecology and Evolution, 2018
Aim ‒ To evaluate the current distribution of the species of the genus Galianthe by track analysis, and to establish the distributional patterns based on the available tectonic information and the biogeographical regionalization of the Neotropical region.
Javier Elias Florentín   +4 more
doaj   +3 more sources

Transmission with Energy Harvesting Nodes in Fading Wireless Channels: Optimal Policies [PDF]

open access: yesIEEE Journal on Selected Areas in Communications, 2011
Wireless systems comprised of rechargeable nodes have a significantly prolonged lifetime and are sustainable. A distinct characteristic of these systems is the fact that the nodes can harvest energy throughout the duration in which communication takes ...
Omur Ozel   +4 more
semanticscholar   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

A harmonized data set of ruminant livestock presence and grazing data for the European Union and neighbouring countries

open access: yesScientific Data
Improving the sustainability of the European livestock sector requires recent data at high spatial resolutions. Only then can we analyse potential negative impacts of livestock related to ecosystem degradation, and positive ones such as preserving ...
Žiga Malek   +3 more
doaj   +1 more source

Near-infrared fluorescence for detection of sentinel lymph nodes in women with cervical and uterine cancers (FILM): a randomised, phase 3, multicentre, non-inferiority trial.

open access: yesThe Lancet Oncology, 2018
BACKGROUND Accurate identification of sentinel lymph nodes in patients with cancer improves detection of metastatic disease and decreases surgical morbidity.
M. Frumovitz   +8 more
semanticscholar   +1 more source

Alveolar Soft Part Sarcoma in Pediatric and Young Adult Patients: A Report From the Children's Oncology Group Study ARST0332

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Alveolar soft part sarcoma (ASPS) is a rare soft tissue sarcoma occurring most commonly in adolescence and young adulthood. Methods We present the clinical characteristics, treatments, and outcomes of patients with newly diagnosed ASPS enrolled on the Children's Oncology Group study ARST0332.
Jacquelyn N. Crane   +11 more
wiley   +1 more source

Features of the work of flat large-span structures

open access: yesВестник Дагестанского государственного технического университета: Технические науки, 2023
Objective. The purpose of the study is to prove the features of the operation of largespan flat structures, which are also taken into account in their design.Method. A technique is presented that makes it possible to reduce span bending moments. Examples
A. K. Yusupov   +2 more
doaj   +1 more source

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