Results 51 to 60 of about 2,301,764 (289)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Relaxation Mechanisms, Structure and Properties of Semi-Coherent Interfaces

open access: yesMetals, 2015
In this work, using the Cu–Ni (111) semi-coherent interface as a model system, we combine atomistic simulations and defect theory to reveal the relaxation mechanisms, structure, and properties of semi-coherent interfaces.
Shuai Shao, Jian Wang
doaj   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Oribatid mites (Acariformes: Sarcoptiformes) in Sub-Antarctic Islands and Antarctica: a track analysis

open access: yesУкраїнський антарктичний журнал
Southern non-marine mites are widely distributed in the continents that developed out of the macrocontinent Gondwana, with similar groups found in Australia, New Zealand, Sub-Antarctic Islands, and southern South America.
Patricio R. De los Ríos-Escalante   +2 more
doaj   +1 more source

Impact of Number of Positive Lymph Nodes and Lymph Node Ratio on Survival of Women with Node-Positive Breast Cancer.

open access: yesEuropean Journal of Breast Health, 2019
Objective This study aimed to evaluate the association of axillary lymph node ratio (LNR) and number of positive lymph nodes (pN) with the risk of breast cancer recurrence and death.
Fabiana Tonellotto   +5 more
semanticscholar   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Improving the representation of cattle grazing patterns in the European Union

open access: yesEnvironmental Research Letters
Improving the sustainability of the European cattle sector requires improved knowledge not only of the density of cattle, but also of the grazing patterns.
Žiga Malek   +6 more
doaj   +1 more source

Application of the Network Analysis in Psychological Research

open access: yesPsychological Topics, 2020
The network approach represents a novel paradigm for exploring relations between psychological constructs and observable variables. According to this approach, variables form an autonomous dynamical system; the psychological construct is therefore not ...
Anamarija Lonza
doaj  

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