Results 71 to 80 of about 2,763,116 (335)

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

The Synergistic Effect of WS₂ and SWNTs on Tribological Performance of Polyether MDI Polyurethane Elastomer under Dry and Wet Friction Conditions

Nanomaterials, 2022
To adapt to the complex application of polyurethane bearings, it is feasible to improve the tribological performance of single polyurethane-based friction materials through the synergistic effect produced by multi-component-lubricating fillers.
Gang Lu, Changgeng Shuai, Yinsong Liu, Xue Yang, Xiaoyang Hu   +4 more
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Optimzation design of resonance changer for marine propulsion shafting in longitudinal vibration

Zhongguo Jianchuan Yanjiu, 2019
[Objectives] The transmission path of the longitudinal vibration of propeller shafting can be changed and the base response attenuated via a Resonance Changer(RC)integrated in the thrust bearing, enabling the natural frequency of the shafting to be ...
Hu Zechao, He Lin, Xu Wei, Li Zhengmin, Zhao Xingqian   +4 more
doaj   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source

Adaptive Narrowband Compensation Algorithm for Active Control of the Pressure Pulsation Line Spectrum in A Liquid Pipeline System

Shock and Vibration
Active noise control technology provides a means for actively controlling pipeline pulsations. The control signal emitted by the secondary source feeds back into the reference input signal, thereby generating a pulsation coupling phenomenon.
Qichao Liu, Wenjing Yu, Guo Cheng
doaj   +1 more source

WHO Environmental Noise Guidelines for the European Region: A Systematic Review on Environmental Noise and Effects on Sleep

International Journal of Environmental Research and Public Health, 2018
To evaluate the quality of available evidence on the effects of environmental noise exposure on sleep a systematic review was conducted. The databases PSYCINFO, PubMed, Science Direct, Scopus, Web of Science and the TNO Repository were searched for non ...
M. Basner, S. Mcguire
semanticscholar   +1 more source

Combustion noise

Proceedings of the Combustion Institute, 2015
AbstractCombustion noise is becoming increasingly important as a major noise source in aeroengines and ground based gas turbines. This is partially because advances in design have reduced the other noise sources, and partially because next generation combustion modes burn more unsteadily, resulting in increased external noise from the combustion.
Dowling, Ann P., Mahmoudi, Yasser
openaire   +3 more sources

Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins

FEBS Open Bio, EarlyView.
We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó, Eszter Nagy‐Kanta, Soma Varga, Edit Andrea Jáger, Csaba István Pongor, Mária Laki, András József Laki, Zoltán Gáspári   +7 more
wiley   +1 more source

A Comparison of Finite Element Analysis (With Additional Aspects) For Predicting the Noise and Vibration for Railway Project in Malaysia

MATEC Web of Conferences, 2019
This paper is about predicting the noise and vibrations for railways project in Malaysia by using Finite Element Analysis method. In recent years, Malaysia is massively developing railways industry.
Yeo Siang Chuan, Lim Meng Hee, Eng Hoe Cheng   +2 more
doaj   +1 more source