Results 51 to 60 of about 2,665,841 (300)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Enhanced Bearing Fault Analysis under Inconstant Loads Conditions by Cosine Weighted K-Nearest Neighbours Model [PDF]
ITM Web of ConferencesBearing faults often lead to machinery failures, underscoring the importance of analyzing bearing vibrations to avert undesirable consequences. Leveraging Artificial Intelligence (AI) in this context benefits from the strides in intelligent data ...
Yap J.S., Lim M.H., Leong M. Salman
doaj +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Review of Underground Storage Tank Condition Monitoring Techniques
MATEC Web of Conferences, 2019 This article aims to provide a comprehensive review on the condition monitoring techniques of underground storage tanks (UST). Generally, the UST has long been a favourite toxic substance reservation apparatus, thanks to its large capacity and minimum ...
Ching Sheng Ooi +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Shock and VibrationActive noise control technology provides a means for actively controlling pipeline pulsations. The control signal emitted by the secondary source feeds back into the reference input signal, thereby generating a pulsation coupling phenomenon.
Qichao Liu, Wenjing Yu, Guo Cheng
doaj +1 more source
Optimzation design of resonance changer for marine propulsion shafting in longitudinal vibration
Zhongguo Jianchuan Yanjiu, 2019 [Objectives] The transmission path of the longitudinal vibration of propeller shafting can be changed and the base response attenuated via a Resonance Changer(RC)integrated in the thrust bearing, enabling the natural frequency of the shafting to be ...
Hu Zechao +4 more
doaj +1 more source
A Novel Adaptive Kalman Filter With Inaccurate Process and Measurement Noise Covariance Matrices
IEEE Transactions on Automatic Control, 2018 In this paper, a novel variational Bayesian (VB)-based adaptive Kalman filter (VBAKF) for linear Gaussian state-space models with inaccurate process and measurement noise covariance matrices is proposed.
Yulong Huang +4 more
semanticscholar +1 more source