Results 61 to 70 of about 32,056 (280)

Urban mobility sustainable plans: Tools and transport policies [PDF]

MATEC Web of Conferences
This paper provides indications on how to develop a Sustainable Urban Mobility Plan (SUMP) in small and medium-sized cities, bringing the case study of an Italian town located in southern Italy, Brindisi. The guidelines are part of the output of the SuMo
Venezia Elisabetta, Gattullo Mariateresa
doaj   +1 more source

strategic approach to noise action planning?

, 2022
Airports are required to manage noise impact owing to a requirement for them to obtain a social license to operate from the public, and to comply with legislation such as the ICAO Balanced Approach and Environmental Noise Directive. The latter requires the development of noise action plans to help direct noise management strategies over long-term ...
openaire   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Evaluation of the urban transportation infrastructure and its urban surroundings in the Iztapalapa County: A geotechnology approach about its management

Cogent Engineering, 2017
The urban transportation infrastructure (UTI) is an essential asset for any city and it affects citizens, governments, economic growth and urban functioning. The UTI is more valuable than ever due to the urbanization process that concentrates more people
Ioannis Chatziioannou, Luis Alvarez-Icaza   +1 more
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An mHealth System for Monitoring Medication Adherence in Obstructive Respiratory Diseases Using Content Based Audio Classification

IEEE Access, 2018
Asthma and chronic obstructive pulmonary disease are obstructive respiratory diseases that affect negatively the quality of life for patients and their families worldwide.
Stavros Nousias, Aris S. Lalos, Gerasimos Arvanitis, Konstantinos Moustakas, Triantafillos Tsirelis, Dimitrios Kikidis, Konstantinos Votis, Dimitrios Tzovaras   +7 more
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A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Noise as an Indicator of Residential Areas’ Quality in the Municipality of Velenje, Slovenia

Kartografija i Geoinformacije, 2014
Noise has been recognized as the air pollutant since it affects the environmental quality. Its effect depends on its level; it may be slightly uncomfortable or so annoying that hinder our business or in extreme cases dangerous to health.
Natalija Špeh, Blaž Barborič
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