Results 51 to 60 of about 6,177,823 (287)

Urban mobility sustainable plans: Tools and transport policies [PDF]

open access: yesMATEC Web of Conferences
This paper provides indications on how to develop a Sustainable Urban Mobility Plan (SUMP) in small and medium-sized cities, bringing the case study of an Italian town located in southern Italy, Brindisi. The guidelines are part of the output of the SuMo
Venezia Elisabetta, Gattullo Mariateresa
doaj   +1 more source

strategic approach to noise action planning?

open access: yes, 2022
Airports are required to manage noise impact owing to a requirement for them to obtain a social license to operate from the public, and to comply with legislation such as the ICAO Balanced Approach and Environmental Noise Directive. The latter requires the development of noise action plans to help direct noise management strategies over long-term ...
openaire   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Affirmative Action Plan, 1999-2000 [PDF]

open access: yes, 1999
Illinois State University Affirmative Action Planhttps://ir.library.illinoisstate.edu/affirmative-action-reports/1009/thumbnail ...
Affirmative Action Plan 1999-00 Working Team,
core   +2 more sources

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Evaluation of the urban transportation infrastructure and its urban surroundings in the Iztapalapa County: A geotechnology approach about its management

open access: yesCogent Engineering, 2017
The urban transportation infrastructure (UTI) is an essential asset for any city and it affects citizens, governments, economic growth and urban functioning. The UTI is more valuable than ever due to the urbanization process that concentrates more people
Ioannis Chatziioannou   +1 more
doaj   +1 more source

An mHealth System for Monitoring Medication Adherence in Obstructive Respiratory Diseases Using Content Based Audio Classification

open access: yesIEEE Access, 2018
Asthma and chronic obstructive pulmonary disease are obstructive respiratory diseases that affect negatively the quality of life for patients and their families worldwide.
Stavros Nousias   +7 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Kwale County Climate Change Action Plan 2023-2027 [PDF]

open access: yes, 2023
The Kwale County Climate Change Action Plan (CCCAP) 2022-2027 is prepared pursuant to Section 19 of the National Climate Change Act, 2016, which mandates counties to develop their climate action plans and integrate the National Climate Action Plan (NCCAP)

core   +1 more source

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