Results 31 to 40 of about 551,283 (308)

Numerical modeling techniques for noise emission of free railway wheels

Railway Engineering Science
In this article, we consider the numerical prediction of the noise emission from a wheelset in laboratory conditions. We focus on the fluid–structure interaction leading to sound emission in the fluid domain by analyzing three different methods to ...
Linus Taenzer, Urs Pachale, Bart Van Damme, Andrea Bergamini, Domenico Tallarico   +4 more
doaj   +1 more source

A Method for Determining the Optimal Location of a Distributed Sensor/Actuator

Shock and Vibration, 1994
The optimal location problem of distributed sensor/actuator for observation and control of a flexible structure is investigated. Using a property of controllability and observability grammian matrices, this approach employs a nonlinear optimization ...
Byeongsik Ko, Benson H. Tongue, Andrew Packard   +2 more
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Effects of Background Sounds on Annoyance Reaction to Foreground Sounds in Psychoacoustic Experiments in the Laboratory: Limits and Consequences

Applied Sciences, 2019
In a variety of applications, e.g., psychoacoustic experiments, virtual sound propagation demonstration, or synthesized noise production, noise samples are played back in laboratories.
Armin Taghipour, Eduardo Pelizzari
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Study on the impact of Gurney flap parameters on rotor performance improvement

Hangkong gongcheng jinzhan
At present, most of the research on installing Gurney flaps is focused on two-dimensional airfoils. The three-dimensional blade model is established to investigate the influence of different Gurney flap parameters on rotor aerodynamic performance ...
LIU Shaoteng, LIU Xiangnan, SHAO Tianshuang, WANG Puyuan   +3 more
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Nonlinear Responses and Stability of an Elastic Suspended Cable System Subjected to Parametrical External Excitations

Nonlinear Engineering, 2017
This research investigates the nonlinear behavior and stability of an elastic suspended cable system under combined parametric and external excitations, with an approach of higher accuracy and reliability.
Dai Liming, Xia Dandan, Chen Changping
doaj   +1 more source

Vibration, acoustic, temperature, and motor current dataset of rotating machine under varying operating conditions for fault diagnosis

Data in Brief, 2023
Rotating machines are often operated under various operating conditions. However, the characteristics of the data varies with their operating conditions.
Wonho Jung, Seong-Hu Kim, Sung-Hyun Yun, Jaewoong Bae, Yong-Hwa Park   +4 more
doaj   +1 more source