Results 51 to 60 of about 755,676 (315)

Efficiency evaluation of a noise barrier

Journal of Environmental Engineering and Landscape Management, 2007
Mechanization of industrial and agricultural production, increase of urban and rural traffic flows, modernization of domestic facilities cause a rapid expansion of acoustic discomfort zones.
Pranas Baltrėnas, Donatas Butkus, Vytautas Nainys, Raimondas Grubliauskas, Jurgita Gudaitytė   +4 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

An Intellectual–Analytical Platform for Assessing the Psychophysiological Load on Flight Instructors

Applied Sciences
This study aimed to develop an intellectual and analytical platform for assessing the psychophysiological load on flight instructors in a flight school (general aviation). As part of this study, an information model for evaluating the working environment’
Miroslav Kelemen, Volodymyr Polishchuk, Martin Kelemen, Miroslav Badida, Marek Moravec   +4 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

The effectiveness of noise protection of the green spaces of the city of Bryansk

RUDN Journal of Ecology and Life Safety
The most serious negative factor for life, and even more so for human recreation in urban conditions, is urban noise, the level of which has increased significantly recently. The city of Bryansk is also an exception - the administrative center of the Non-
Victoria M. Nesterenko
doaj   +1 more source

Light and noise conditions of buildings for breeding dairy cows

Research in Agricultural Engineering, 2010
Check measurement of the illuminance, the uniformity ratio of illuminance and noise level was made in the selected stable building to prove quality of lightning both for service workers and the cattle. The measurement discovered that the noise level, the
M. Šístková, A. Peterka, B. Peterka
doaj   +1 more source

福建省地震台网预警能力评估

Dizhen xuebao, 2023
由于常用的均方根值法和噪声功率谱法不能消除不同传感器记录的噪声干扰，为提高噪声水平计算的准确度，本文选用最大概率峰值位移作为背景噪声评估指标。基于可靠的噪声数据，借鉴震级-最大距离监测能力法并考虑预警时效，提出了地震预警最小震级评估方法，系统评估福建三类传感器网及其融合网的地震预警最小震级和预警首报时间。结果表明：测震强震融合网的地震预警最小震级高于单测震网，但明显低于强震网；强震烈度计融合网与单烈度计网的结果相近；三网融合后95%区域的地震预警最小震级约为ML3.2。由于烈度计网比测震和强震网密集 ...
Xiuzhen You, Binhua Lin, Jun Li, Yang Guo, Weiheng Yu, Shuilong Li   +5 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Studying the Effect of Noise Barrier Characteristics on Traffic Noise in Urban Areas

Civil and Environmental Engineering
This research aims to identify the optimal noise concrete barrier mix through two critical stages. The initial step involves calibrating a traffic noise model via a field survey at 18 locations, encompassing volume counts and noise levels at varying ...
Ramadan Ibrahim, Salah Tahra, Alhariri Osama   +2 more
doaj   +1 more source