Results 61 to 70 of about 755,676 (315)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Noise landing charges and passengers' choice of airport. [PDF]

, 1995
This study demonstrates how aircraft noise can be translated into a form of landing charge. The objectives of the thesis were to develop noise landi'ng charges for six of the major airports in England and to determine what the implication it has on ...
Yeahiya, Mohammed
core  

Evaluate traffic noise level based on traffic microsimulation combined with a refined classic noise prediction method

, 2014
In this paper, a refined classic noise prediction method based on the VISSIM and FHWA noise prediction model is formulated to analyze the sound level contributed by traffic on the Nanjing Lukou airport connecting freeway before and after widening.
He, Jie, Mark King, Chen Zhang, Zhang, Chen, Jie He, King, Mark, Wang, Haifeng, Haifeng Wang   +7 more
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

What’s that noise—tackling sound pollution in the NICU: a systematic review

Frontiers in Pediatrics
BackgroundPreterm infants are highly susceptible to environmental influences due to the immaturity of their sensory and neurological systems. In neonatal intensive care units (NICUs), ambient noise frequently exceeds recommended thresholds and may ...
Vito Giordano, Sophie Mandl, Lisa Bartha-Doering, Christoph Reuter, Matthias Bertsch, Brigitte Wildner, Sophie Stummer, Katrin Klebermass-Schrehof, Marcus Maeder, Angelika Berger, Philipp Deindl, Philipp Deindl   +11 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Noise and levels of processing

Acta Psychologica, 1981
Abstract Three experiments investigated the view that people make more use of relatively surface levels of coding when noise is present, neglecting semantic levels of analysis. In experiment 1 subjects classified words in different ways and then recalled as many as possible. Subjects who received the noise conditions in the order noise-quiet recalled
Andrew P. Smith, Donald E. Broadbent
openaire   +1 more source

Wind turbines noise measurements inside homes

, 2019
Wind energy is a primary source for achieving the objectives of the Oil Free Society. However, noise emission is often a significant problem encountered during wind turbines operation.
Ciaburro G., Trematerra A., Iannace G., Berardi U.   +3 more
core