Results 61 to 70 of about 844,062 (293)
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Understanding perceived tranquillity in urban Woonerf streets: case studies in two Dutch cities
Within the current urbanised society, the call for calm and quiet areas seems more pressing than ever. Such tranquil environments like the Woonerf streets in the Netherlands allow a more human-centred design, where traffic has a restricted speed limit of
Leereveld Theun +2 more
doaj +1 more source
The purpose of this research was to design and deploy tools that apply the concept of citizen observatories and empowering citizens in the assessment of acoustic comfort in public places. The research applies an iterative cycle of design and this article
Aspuru Itziar +3 more
doaj +1 more source
The soundscape of the Trevi fountain in Covid-19 silence
This paper is devoted to the analyses of sound-scape at fontana di Trevi in Rome (Italy) with the aim to compare its characteristics during the Italian lockdown due to the (Sars-COV2) Covid-19 sanitary emergency and its characteristics before and after ...
De Lauro Enza +2 more
doaj +1 more source
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
The aim of the paper is to define a method for evaluating infrastructural interventions for the mitigation of noise generated by roads based on multi-criteria analysis which considers a series of parameters (environmental, social, economic and health ...
D’Alessandro Francesco +3 more
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
This paper presents a bibliometric and critical review of auditory and non-auditory health impacts due to road traffic noise exposure. The paper discusses the general trends of studies conducted in the research domain using the bibliometric network ...
Manohare Manish +3 more
doaj +1 more source
Influence of a Random Telegraph Process on the Transport through a Point Contact
We describe the transport properties of a point contact under the influence of a classical two-level fluctuator. We employ a transfer matrix formalism allowing us to calculate arbitrary correlation functions of the stochastic process by mapping them on ...
A. Peres +29 more
core +2 more sources
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source

