Results 51 to 60 of about 608,210 (316)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Firewall insulation package simulation and noise auralisation for EV [PDF]

open access: yes, 2019
EV vehicle are now having a great influence on the market, with the number of vehicles sold increasing every year. For the engineer, the introduction of full electric vehicles means new challenges, a change in paradigms and new goals to achieve.
Qingmei Chang   +2 more
core  

DTI denoising for data with low signal to noise ratios [PDF]

open access: yes, 2005
Low signal to noise ratio (SNR) experiments in diffusion tensor imaging (DTI) give key information about tracking and anisotropy, e. g., by measurements with small voxel sizes or with high b values.
Prigarin, Sergej M.   +6 more
core   +1 more source

Parameter Estimation of Signal-Dependent Random Noise in CMOS/CCD Image Sensor Based on Numerical Characteristic of Mixed Poisson Noise Samples

open access: yesSensors, 2018
Parameter estimation of Poisson-Gaussian signal-dependent random noise in the complementary metal-oxide semiconductor/charge-coupled device image sensor is a significant step in eliminating noise.
Yu Zhang, Guangyi Wang, Jiangtao Xu
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Adaptive myriad filter with time-varying noise- and signal-dependent parameters

open access: yesРадіоелектронні і комп'ютерні системи, 2022
The research subject of this article is the methods of locally adaptive filtering of non-stationary signals. The goal is to develop a locally-adaptive algorithm for non-stationary noise (from the viewpoint of its time-varying variance) suppression in ...
Nataliya Tulyakova, Oleksandr Trofymchuk
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Impulse Noise Parameter Assessment in a Batch Radio Channel

open access: yesРоссийский технологический журнал, 2019
Modern radio communication means to provide safe data transmission due to adapting radio channel to the actual noise environment. It is impossible to conduct proper comparative tests on various radio stations offered by manufacturers and to compare ...
A. Yu. Bekkiev, V. A. Makoviy
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

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