Results 71 to 80 of about 4,484,233 (290)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Aerodynamic noise from a train pantograph

, 2014
Many studies have shown that when the speed of high speed trains exceeds around 300km/h, aerodynamic noise becomes the most significant noise source. The pantograph, or current collector, is mounted on the top of the train and is therefore not shielded ...
Liu, Xiaowan, Hu, Zhiwei, Jurdic, Vincent, Thompson, David J.   +3 more
core   +1 more source

Active noise reduction system

Archives of Acoustics, 2014
In this article, active noise reduction system has been described. The ANR system was made on basis of finite impulse response filter and realised algorithms LMS or NLMS.
Wojciech CIESIELKA
doaj  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Adaptive Noise Reduction System

Interdisciplinary Description of Complex Systems, 2013
Noise is an all-present environment pollutant, considered to be one of the greatest contemporary pollutants. World-wide, co-ordinated actions are conducted in order to develop systems which minimise the noise influence onto society.In this article we ...
Ivana Ropuš, Vesna Alar, Biserka Runje
doaj  

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Airfoil noise reductions through leading edge serrations

This paper provides an experimental investigation into the use of leading edge (LE) serrations as a means of reducing the broadband noise generated due to the interaction between the aerofoil’s LE and impinging turbulence.
Joseph, P.F., Polacsek, C., Narayanan, S., Kim, J.W., Haeri, S., Chaitanya, P.   +5 more
core   +1 more source

Representation Transfer via Invariant Input-driven Continuous Attractors for Fast Domain Adaptation

Communications Biology
Conventional end-to-end deep neural networks often degrade under domain shifts and require costly retraining when deployed in unpredictable, noisy environments.
Tie Xu, Shengdun Wu, Junwen Luo, Yao Yang, Feng Lin, Junjie Jiang, Guozhang Chen, Dongping Yang   +7 more
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Perforated fairings for landing gear noise control

, 2008
Landing gears of commercial aircraft make an important contribution to total aircraft noise in the approach configuration. Using fairings to shield components from high speed impingement reduces noise.
Boorsma, K., Koen Boorsma, Xin Zhang, Molin, N., Zhang, X., Nicolas Molin   +5 more
core   +2 more sources