Results 41 to 50 of about 673,965 (277)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
SensorsThis paper proposes a point cloud post-processing method based on the minimum spanning tree (MST) and depth-first search (DFS) to extract laser stripe centerlines from the complex inner surfaces of deep holes.
Huifu Du +3 more
doaj +1 more source
Image noise reduction based on applying adaptive thresholding onto PDEs methods
The Journal of Engineering, 2017 In this study the authors present a novel image denoising method based on applying adaptive thresholding on partial differential (PDEs) methods. In the proposed method the authors utilise the adaptive thresholding to blend the total variation filter with
Ali Abdullah Yahya +4 more
doaj +1 more source
SmoothGrad: removing noise by adding noise
, 2017 Explaining the output of a deep network remains a challenge. In the case of an image classifier, one type of explanation is to identify pixels that strongly influence the final decision. A starting point for this strategy is the gradient of the class score function with respect to the input image.
Smilkov, Daniel +4 more
openaire +2 more sources
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Remote SensingThe high-precision motion state analysis of space targets has important scientific value and application potential in the fields of geodynamics, geodesy, space collision warning and avoidance, and the capture, recovery, and removal of space debris.
Yanning Zheng +7 more
doaj +1 more source
Innovative Demodulation Scheme for Coherent Detectors in CMB Experiments
, 2012 We propose an innovative demodulation scheme for coherent detectors used in cosmic microwave background polarization experiments. Removal of non-white noise, e.g., narrow-band noise, in detectors is one of the key requirements for the experiments.
Chinone, Y. +5 more
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Algorithms of statistical anomalies clearing for data science applications
Sistemnì Doslìdženâ ta Informacìjnì Tehnologìï, 2023 The paper considers the nature of input data used by Data Science algorithms of modern-day application domains. It then proposes three algorithms designed to remove statistical anomalies from datasets as a part of the Data Science pipeline.
Oleksii Pysarchuk +3 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source