Results 41 to 50 of about 99,611 (256)

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source

Speech enhancement by LSTM-based noise suppression followed by CNN-based speech restoration

EURASIP Journal on Advances in Signal Processing, 2020
Single-channel speech enhancement in highly non-stationary noise conditions is a very challenging task, especially when interfering speech is included in the noise.
Maximilian Strake, Bruno Defraene, Kristoff Fluyt, Wouter Tirry, Tim Fingscheidt   +4 more
doaj   +1 more source

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao, Rongwei Du, Zhujun Wang, Yang Gao, Meiling Cheng, Xianglong Wang, Wen Wu   +6 more
wiley   +1 more source

A Review of Neural Network-Based Image Noise Processing Methods

Sensors
This review explores the current landscape of neural network-based methods for digital image noise processing. Digital cameras have become ubiquitous in fields like forensics and medical diagnostics, and image noise remains a critical factor for ensuring
Anton A. Volkov, Alexander V. Kozlov, Pavel A. Cheremkhin, Dmitry A. Rymov, Anna V. Shifrina, Rostislav S. Starikov, Vsevolod A. Nebavskiy, Elizaveta K. Petrova, Evgenii Yu. Zlokazov, Vladislav G. Rodin   +9 more
doaj   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

Random noise suppression of seismic data based on CEEMD-MSSA

矿业科学学报
Random noise is one of the common noises in seismic data, which has a direct impact on high-resolution imaging processing and fine interpretation of seismic data. Random noise attenuation methods based on the low-rank hypothesis of seismic data have been
WANG Shubin, LIU Yulin, LI Xiaoli, LIN Peng, GAO Lijun   +4 more
doaj   +1 more source

Perceptual Enhancement of Low Light Images Based on Two-Step Noise Suppression

IEEE Access, 2018
Low-light images are seriously corrupted by noise due to the low signal-to-noise ratio. In low intensity, just-noticeable-difference (JND) is high, and thus the noise is not perceived well by human eyes.
Haonan Su, Cheolkon Jung
doaj   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Design of a Dual-Path Speech Enhancement Model

Applied Sciences
Although both noise suppression and speech restoration are fundamental to speech enhancement, many Deep neural network (DNN)-based approaches tend to focus disproportionately on one, often overlooking the importance of their joint handling. In this study,
Seorim Hwang, Sung Wook Park, Youngcheol Park   +2 more
doaj   +1 more source