Results 151 to 160 of about 11,770 (301)

A Longitudinal Exploratory Case-Series Comparing Morphological Trajectories in Four Early-Implanted Greek-Cypriot Children and Eight Typically Hearing Peers. [PDF]

Brain Sci
Yiangou E, Christodoulou Devledian M, Spanoudis G.   +2 more
europepmc   +1 more source

Digoxin Alleviates Osteoarthritis by Inhibiting Macrophage Extracellular Trap Formation via Disruption of the LSP1‐SOD1 Interaction

Advanced Science, EarlyView.
Synovial macrophages in osteoarthritis upregulate LSP1, which directly binds and inhibits SOD1, triggering a redox imbalance that activates both NOX and mitochondrial ROS pathways. This cascade drives the release of macrophage extracellular traps (METs), causing chondrocyte damage and disease progression.
Yankai Pan, Xinzhe Feng, Chuanju Liu, Jianfei Tong, Zhi Li, Chenxu Liu, Yutong Dong, Chen Meng, Yihong Xu, Weidong Xu   +9 more
wiley   +1 more source

Same Sentences, Different Grammars, Different Brain Responses?: An MEG Study on Case and Agreement Encoding in Hindi and Nepali Split-Ergative Structures. [PDF]

Neurobiol Lang (Camb)
Chacón DA, Shrestha S, Dillon BW, Bhatt R, Almeida D, Marantz A.   +5 more
europepmc   +1 more source

Structural Control of Stromal‐Immune Coupling by COL24A1 Underlies Pregnancy Maintenance

Advanced Science, EarlyView.
COL24A1 emerges as a collagen‐associated regulator of maternal‐fetal interface homeostasis. Its deficiency promotes a maladaptive TIMP1‐high stromal state, impaired ECM turnover, collagen accumulation, and stromal–immune dysregulation, contributing to pregnancy loss.
Teng Wu, Lingling Xie, Wenyi Liu, Hanjie Mo, Chengshu Xie, Jing Tang, Zhaorui Wang, Peixuan Lan, Jianping Zhang, Jie Gao, Qionglan Tang, Chunwei Cao, Hui Chen   +12 more
wiley   +1 more source

Processing ergativity in compound light verb constructions: electrophysiological evidence from Hindi. [PDF]

Front Hum Neurosci
Mathew AM, Muralikrishnan R, Gulati M, Bhattamishra S, Choudhary KK.   +4 more
europepmc   +1 more source

Mechanism‐Informed Language Modeling and Oxygenated 3D Screening Identify Berberine–Enzalutamide Synergy in Prostate Cancer Models

Advanced Science, EarlyView.
By integrating knowledge‐augmented artificial intelligence with an oxygen‐supplemented 3D screening platform, a synergistic interaction between berberine and enzalutamide is identified. The framework integrates compound mechanisms of action with disease‐relevant signaling context to prioritize candidate combinations and generate testable pathway‐based ...
Chih‐Hui Lo, Katie Shi, Lina Kafadarian, Alexandra Bermudez, Johnny Diaz, Liam Edwards, Yunqi Hong, Ziyi Chen, Hyeonji Hwang, Weihong Yan, Alan Levinson, Robert Damoiseaux, Cho‐Jui Hsieh, Tanya Stoyanova, Andrew S. Goldstein, Neil Y.C. Lin   +15 more
wiley   +1 more source

Tumor‐Intrinsic HEXB Drives Endothelial‐To‐Mesenchymal Transition and Confers Resistance to Anti‐Angiogenic Therapy in Glioblastoma

Advanced Science, EarlyView.
This study elucidates how glioblastoma tumors develop resistance to anti‐VEGF therapy through endothelial‐to‐mesenchymal transition (Endo‐MT). The researchers identify a novel signaling pathway where tumor‐derived HEXB stabilizes HSP60 to drive this vascular reprogramming.
Tianqi Liu, Xin Chen, Tao Sun, Jianqi Wu, Haixu Yan, Xing Liu, Hongda Lin, Xiangyu Wang, Ziao Xiao, Yang Xu, Qiang Fu, Peng Cheng, Wen Cheng, Anhua Wu   +13 more
wiley   +1 more source

Sécurisation du circuit du médicament expérimental dans les services investigateurs en cas de dispensation non nominative par la méthode AMDEC. [PDF]

Can J Hosp Pharm
Hinterlang M, Assefi M, Glasman P, Silvain J, Brugier D, Antignac M, Charbonnier-Beaupel F, Metz C.   +7 more
europepmc   +1 more source

Nominative subjects can’t move to the left periphery in Japanese

This paper attempts to argue convincingly that nominative subjects in Japanese cannot move to Spec-C if they are phonetically realized; in fact, they should remain in Spec-T from the viewpoint of the nominative case assignment mechanism in ...
Moritake, Nozomi, Nishioka, Nobuaki
core   +1 more source

Transitioning to nonpunitive school policies for addressing student substance use: Qualitative interviews with key school administrators

American Journal of Community Psychology, EarlyView.
Abstract Recent policy change in Massachusetts encourages schools to limit their use of exclusionary discipline to “extraordinary circumstances,” but little work has explored the opportunities and challenges of transitioning to nonpunitive practices after student substance use infractions in schools.
Kristina Conroy, M. Grace Albright, Kendall B. Roberts, Meghan A. Costello, Anthony J. Jannetti, Alexis R. Wing, Randi M. Schuster   +6 more
wiley   +1 more source