Results 31 to 40 of about 4,293 (313)

Case Endings in Standard Arabic

open access: yesالآداب, 2018
This study aims briefly at describing and analyzing some aspects of Case endings in Standard Arabic. This is because that Case seems to play a significant role in the grammar of not only Arabic but also in the grammar of many other languages.
محمد علي محمد قرابش
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

CD4+ Tregs Drive Post‐Ischemic Sprouting Angiogenesis via Endothelial YY1/MAML1 Reactivation

open access: yesAdvanced Science, EarlyView.
ABSTRACT Microvascular complications of diabetes are chronic diseases of small vessels. We previously found that CD4+ regulatory T‐cells (Tregs) are markedly reduced in type 2 diabetes (T2D) after ischemic injury in both mice and humans, and that Treg deficiency in immunodeficient mice impairs vascular regeneration.
Hang Qu   +10 more
wiley   +1 more source

Voice and Modal Verbs in Estonian; 173-186 [PDF]

open access: yesLinguistica Uralica, 2007
The interaction of voice and modal verbs in Estonian confirms the impersonal nature of the basic voice opposition in Estonian and clarifies the constraints on impersonalization.
Reeli Torn-Leesik
doaj   +1 more source

Decoding IGLL5 Mutation‐Mediated BCR Signaling: A Novel Mechanism of CD8+ T Cell Exhaustion and Ocular MALT Lymphoma Progression

open access: yesAdvanced Science, EarlyView.
OAML harbors recurrent IGLL5 mutations that reinforce CD79A/CD79B‐associated BCR signaling. Mechanistic analysis of the S47G and A54G variants reveals induction of CXCL10/CXCL11, enhanced CD8+ T‐cell recruitment, and exhaustion‐associated dysfunction, supporting an immune‐tolerant niche.
Andi Zhao   +12 more
wiley   +1 more source

Set-theoretic Analysis of Nominative Data [PDF]

open access: yesComputer Science Journal of Moldova, 2015
In the paper we investigate the notion of nominative data that can be considered as a general mathematical model of data used in computing systems. The main attention is paid to flat nominative data called nominative sets.
Volodymyr G. Skobelev   +2 more
doaj  

On Determination Method for Resolution of Secondary Electron Images in Scanning Electron Microscopy

open access: yesAdvanced Science, EarlyView.
An idealized SEM, termed Rayleigh's microscope, is constructed by Monte Carlo simulation to represent imaging conditions that just satisfy the Rayleigh criterion. Based on this physically defined model, sharpness–resolution conversion curves are established and combined with the Rose criterion, enabling automated resolution evaluation from practical ...
Tongfang Yang, Yanbo Zou, Zejun Ding
wiley   +1 more source

Ergative Verbs in English and Arabic

open access: yesمجلة كلية الفقه
Ergativity is one the distinctive features that differentiate between two types of languages: ergative languages such as Basque and Eskimo languages and non-ergative languages such as Indo European languages.
Asst. Prof. Dr. Ameer Ali Hussein Al Majtoomy   +1 more
doaj   +1 more source

On the subject-orientation of the dispositional middle construction

open access: yesLinguistics, 2023
This article argues against the claim that the dispositional middle construction is always subject-oriented, by discussing dispositional constructions in Japanese and impersonal middle constructions formed with the causative verb lassen ‘let’ in German ...
Oya Toshiaki
doaj   +1 more source

Tumor‐Derived LAMB3 Drives Immunosuppressive LRRC15+ Fibroblast Formation During Pancreatic Ductal Adenocarcinoma Development

open access: yesAdvanced Science, EarlyView.
A single‐cell atlas of pancreatic ductal adenocarcinoma development reveals progressive ductal‐fibroblast‐immune crosstalk. Tumor‐derived LAMB3 drives the formation of immunosuppressive LRRC15+ fibroblasts through the ITGB1/FAK/MAPK/FOSL2 signaling. Glycolytic reprogramming upregulates LAMB3 and correlates with LRRC15+ fibroblast enrichment.
Xuqing Shi   +23 more
wiley   +1 more source

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