Results 51 to 60 of about 11,770 (301)

Pre‐Regenerative Endothelial Cells Empowered by Antler Blood Exosomes Orchestrate Peripheral Nerve Repair

open access: yesAdvanced Science, EarlyView.
The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang   +11 more
wiley   +1 more source

Thymosin Alpha‐1 Provides Direct Neuroprotection by Engaging the Orexin Receptor HCRTR1 to Suppress Neuronal Necroptosis

open access: yesAdvanced Science, EarlyView.
In this study, we unveil a thymus‐brain endocrine axis wherein Tα1 engages HCRTR1 to inhibit RIPK3‐mediated necroptosis. This study nominates the Tal‐HCRTR1‐RIPK3 axis as a potent and clinically translatable therapeutic target for stroke and neurodegeneration.
Xinmei Kang   +11 more
wiley   +1 more source

Nominative Potential of the Word Anguish

open access: yesRUDN Journal of Language Studies, Semiotics and Semantics
The prerequisite for resolving the question of the nominative system is the recognition of nominative activity as a subject of linguistic science. The function of nominative activity, which consists of producing nominative units that verbalize and ...
Lazzat K. Zhanalina, Irina V. Kotlyarova
doaj   +1 more source

КОМУНІКАТИВНО-ПРАГМАТИЧНІ ВИМІРИ НОМІНАТИВНИХ РЕЧЕНЬ В АНГЛОМОВНОМУ ХУДОЖНЬОМУ ТЕКСТІ / COMMUNICATIVE AND PRAGMATIC DIMENSIONS OF NOMINATIVE SENTENCES IN ENGLISH LITERARY TEXT

open access: yesАктуальні питання суспільних наук та історії медицини, 2017
Томусяк А. Коммуникативно-прагматические измерения номинативных предложений в англоязычном художественном тексте. В статье проведен анализ односложных номинативных предложений с коммуникативно-прагматической точки зрения.
Аліна ТОМУСЯК
doaj   +1 more source

The Nominative Field of HAPPINESS Concept in the Middle English and Modern English Periods

open access: yesДискурс, 2023
Introduction. The article presents the result of the diachronical research of HAPPINESS concept nominative field. The research was conducted on the basis of English explanatory dictionaries and texts of corpus databases, using the methods of corpus ...
E. A. Nilsen, E. A. Okulova
doaj   +1 more source

Single‐Cell Transcriptomic Analysis of Tumor Heterogeneity and the Microenvironment in Pseudomyxoma Peritonei

open access: yesAdvanced Science, EarlyView.
This study presents a single‐cell atlas of pseudomyxoma peritonei spanning primary and paired metastatic lesions. Distinct epithelial substates, stromal remodeling, immune exclusion, lipid metabolic reprogramming, and a candidate angiogenic network were identified in metastatic lesions.
Xi Li   +14 more
wiley   +1 more source

Nominative Signature: Application, Security Model and Construction [PDF]

open access: yes, 2007
Since the introduction of nominative signature in 1996, there have been only a few schemes proposed and all of them have already been found flawed. In addition, there is no formal security model defined.
Willy Susilo   +6 more
core   +1 more source

SOX5 Orchestrates Malignant Evolution via Promoter‐Centric Chromatin Remodeling in MYC‐Driven B‐Cell Lymphoma

open access: yesAdvanced Science, EarlyView.
In MYC‐enforced B‐cell lymphoma, SOX5 occupies promoter‐proximal regulatory regions and is associated with reduced chromatin accessibility at the PCNP locus. PCNP repression promotes proliferative remodeling by limiting apoptosis and cell‐cycle restraint.
Yiyou Mao   +6 more
wiley   +1 more source

AI‐Assisted Engineering of Glycyrrhizic Acid/Simvastatin Nanocrystals for Multifunctional Treatment of Bacterial Osteomyelitis

open access: yesAdvanced Science, EarlyView.
Through AI‐assisted screening from FDA‐approved API to overcome the limitations of bacterial osteomyelitis treatment, glycyrrhizic acid and simvastatin are identified as a multifunctional combination capable of self‐assembling into mechanism‐targeting nanocrystals that effectively neutralize reactive oxygen species, suppress M1 macrophage polarization,
Yu Han   +11 more
wiley   +1 more source

Nominal SOS

open access: yesElectronic Notes in Theoretical Computer Science, 2012
AbstractPlotkinʼs style of Structural Operational Semantics (SOS) has become a de facto standard in giving operational semantics to formalisms and process calculi. In many such formalisms and calculi, the concepts of names, variables and binders are essential ingredients. In this paper, we propose a formal framework for dealing with names in SOS.
Matteo Cimini   +3 more
openaire   +3 more sources

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