Results 161 to 170 of about 116,458 (273)
This study is the first to identify a novel neutrophil subpopulation, N4, that is closely associated with the progression of cervical cancer. Characterized by high PLAU expression and specific interactions with tumor cells, N4 neutrophils were shown to promote tumor growth and immune modulation.
Ze Wang +7 more
wiley +1 more source
The safety and antitumor activity of crizotinib at a dose of 165 mg/m2 BID were evaluated in 16 patients with ALK‐positive ALCL in Japan. The most common grade 3 or 4 adverse event was neutropenia. The steady‐state Cmax and AUCtau of crizotinib at 165 mg/m2 BID were higher than expected. The objective response rate was 72.7% (90% CI, 43.6%–92.1%) among
Tetsuya Mori +12 more
wiley +1 more source
Development and internal validation of a nomogram to predict in-hospital mortality in patients with cirrhosis and acute kidney injury receiving continuous renal replacement therapy: A retrospective cohort study. [PDF]
Liao T +5 more
europepmc +1 more source
Nomogram for Anaesthetic Uptake [PDF]
H J, Lowe, J F, Viljoen
openaire +2 more sources
We generated endocrine‐resistant BC cell lines and identified CLEC3A, PCDH10, and ST3GAL1 as key endocrine‐resistant genes. More importantly, we validated their role in mediating resistance through PI3K‐AKT signalling and developed a predictive ERS with strong clinical relevance.
Liqin Ping +7 more
wiley +1 more source
A parsimonious nomogram for individualized prediction of 1-year functional outcome after STN-DBS in Parkinson's disease: a single-center retrospective study. [PDF]
Zhang Y, Zhu Q, Fang B, Geng F.
europepmc +1 more source
Mechanism of ITGB2 in Osteoclast Differentiation in Osteoarthritis
In osteoclast precursors, higher ITGB1 than ITGB2 expression increases ITGA2‐ITGB1 integrin. In OA, extracellular signals upregulate ITGB2 and downregulate ITGB1, enhancing ITGA2‐ITGB2 integrin. This activates Rac1 to Rac‐GTP, driving osteoclast differentiation. Hyperactive subchondral osteoclasts accelerate OA progression.
Yang Yang +16 more
wiley +1 more source
Construction and validation of a nutritional status (CONUT)-based nomogram for predicting prolonged hematological toxicity in relapsed/refractory multiple myeloma after CAR-T cell therapy. [PDF]
Xu P +8 more
europepmc +1 more source

