Results 231 to 240 of about 106,048 (268)

Integrating Multimodal MRI Habitat and Transformer‐Based Pathomics to Predict High‐Risk Molecular Subtypes and Explore Biological Mechanisms in Adult Diffuse Gliomas

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
Based on the 2021 WHO CNS5 guidelines, this study introduces an integrated high‐risk molecular classification for gliomas and constructs a predictive model by combining multimodal MRI habitat imaging, Transformer‐based WSI pathomics, and clinical information.
Wenju Niu   +9 more
wiley   +1 more source

Association of Reproductive Factors and Postmenopausal Sex Hormones With Cognitive Impairment in Postmenopausal Women With Parkinson's Disease

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
Shorter reproductive lifespan constitutes an independent risk factor for cognitive impairment among postmenopausal women with Parkinson's disease, while postmenopausal sex‐hormone levels exhibit no relevant correlation with such cognitive impairment.
Wen‐Zheng Hu   +10 more
wiley   +1 more source

A novel nomogram for predicting subsyndromal delirium in critically ill patients with diabetes. [PDF]

open access: yesFront Endocrinol (Lausanne)
Wei C   +8 more
europepmc   +1 more source

Multimodal Characterization of APOE ε4‐Associated Neurovascular Heterogeneity Using Retinal, Plasma, and Neuroimaging Biomarkers in Alzheimer's Disease

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
The LASSO and logistic regression model integrate neuroimaging measures and retinal vascular biomarkers to identify key predictors of APOE ε4 status, improving genotype‐specific stratification. The model's calibration curve and decision curve analysis demonstrate improved discrimination and clinical utility when retinal vascular data are integrated ...
Haoran Cheng   +8 more
wiley   +1 more source

Long‐Term Prognosis, Residual Recurrence Risk, and Postoperative Management After Pathological Complete Response in Rectal Cancer

open access: yesCancer Nexus, Volume 2, Issue 4, October 2026.
This graphical abstract summarizes the post‐pCR clinical pathway in locally advanced rectal cancer. After neoadjuvant radiotherapy and systemic therapy followed by surgery, patients achieving pCR (ypT0N0) generally have durable disease control, although residual risks of local and distant recurrence remain. Risk assessment, guideline‐based surveillance,
Jia‐ang Wang   +3 more
wiley   +1 more source

Gallstone formation and hepatobiliary tumour risk: Clinical implications of the bile acid–gut microbiota axis

open access: yesClinical and Translational Discovery, Volume 6, Issue 5, October 2026.
1. Irregular dietary patterns (e.g., late breakfast, reduced meal frequency) upregulate the bai gene cluster by disrupting cholecystokinin (CCK) release rhythms and gut microbiota circadian rhythms, leading to increased production of secondary bile acids, particularly DCA. High‐carbohydrate dietary patterns increase gallstone risk (OR = 1.329).
Rui Li   +6 more
wiley   +1 more source

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