Results 241 to 250 of about 106,048 (268)

Multi‐omics integration and machine learning identify an ACKR1+ endothelial cell‐based lactate‐immune signature associated with carotid plaque vulnerability and progression

open access: yesClinical and Translational Medicine, Volume 16, Issue 10, October 2026.
ACKR1+ endothelial cells mark intraplaque neovessels with hyperactive glycolysis and lactate metabolism. Lactate, HIF‐1α and CXCL12 link this state to CXCR4+ CD8+ T‐cell recruitment in situ. SLC16A3 and SLC16A4 serve as quantitative readouts of this lactate–immune state.
Ji Zhang   +10 more
wiley   +1 more source

Integrated Multi‐Omics and Single‐Cell Analyses Implicate NOX4 as an Icariin‐Associated Oxidative Stress Regulatory Node in Gastric Cancer

open access: yesFood Science &Nutrition, Volume 14, Issue 10, October 2026.
NOX4 represents a candidate icariin‐associated regulatory node in gastric cancer and may contribute to the cellular response to icariin through redox‐related signaling. ABSTRACT Icariin, a prenylated flavonoid glycoside from Epimedium species, is a representative dietary polyphenol with antioxidant, anti‐inflammatory, and antitumor properties.
Na Liang   +8 more
wiley   +1 more source

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