Prediction of distant metastasis and survival of appendiceal cancer patients: a SEER population-based study. [PDF]
Guo Y, Ji Y, Ren Y, Yao L, Yu J.
europepmc +1 more source
TCF/LEF family transcription factors: Molecular landscape and prognostic scoring in pan‐cancer
This study provides a comprehensive molecular landscape of TCF/LEF family transcription factors across 33 cancer types. We developed a TCF/LEF‐based prognostic score that correlates with immune infiltration, metabolic reprogramming and drug sensitivity, offering a robust transcriptomic signature for predicting patient survival and therapeutic response.
Zhengjun Yang +8 more
wiley +1 more source
Development and validation of prognostic nomograms based on peripheral blood T-cell counts and their dynamic changes for patients with nasopharyngeal carcinoma receiving radiotherapy. [PDF]
Weng K +6 more
europepmc +1 more source
Abstract Tumor‐educated platelets (TEPs) are emerging as a compelling frontier in liquid biopsy, functioning as dynamic, systemic sensors that sequester and process tumor‐derived biomolecules. This interaction imprints an integrated molecular signature of malignancy—spanning the transcriptome, proteome, lipidome, and crucially, the captured genome ...
Whi‐An Kwon +5 more
wiley +1 more source
Development and external validation of nomograms for predicting prostate cancer and clinically significant prostate cancer in patients with PSA between 4 and 20 ng/mL. [PDF]
Wu K +7 more
europepmc +1 more source
Drug Critical Limits for Urgent Physician Notification
Critical limits represent quantitative decision thresholds for drugs that require immediate clinician notification and potential life‐saving intervention. United States hospitals lack a national standard for drug critical limits. We collected critical limits from 417 US hospitals across all 50 states and Washington, D.C.; of these, 411 maintained drug ...
Elina Kuang +3 more
wiley +1 more source
Differential risk profiles for geriatric depression, anxiety, and sleep disturbances in rural China: insights from the Taierzhuang cohort. [PDF]
Zhang R +9 more
europepmc +1 more source
What's New? PD‐L1 is a reliable biomarker for predicting immunotherapy efficacy in patients with non‐small‐cell lung cancer lacking oncogenic driver mutations. However, its significance in patients with driver mutations remains unclear. In this study of 273 patients with stage IV non–‐small‐cell lung cancer harboring diverse driver alterations and PD ...
Xiaoxiao Fan +7 more
wiley +1 more source
Development of a Prognostic Nomogram Model and Establishment of a Risk Stratification System Based on the Naples Prognostic Score for Patients with Oropharyngeal Squamous Cell Carcinoma Who Have Undergone Radical Surgery. [PDF]
Meng X +9 more
europepmc +1 more source
Abstract Gastric signet ring cell carcinoma (GSRCC) is a special type of gastric cancer common in young women. Diffuse gastric cancer (DGC) begins with intramucosal lesions comprising differentiated GSRCC cells. Genetically, GSRCC and DGC are clonally identical, with their morphology influenced by extracellular Wnt signaling.
Qian Wang +5 more
wiley +1 more source

