Results 181 to 190 of about 34,329 (314)

Diagnostic Accuracy Studies: Sensitivity, Specificity, and Beyond

open access: yesJournal of Periodontal Research, EarlyView.
This methodological article covers key diagnostic accuracy measures, common pitfalls in diagnostic accuracy studies, and how evidence should progress from diagnostic accuracy to clinical effectiveness, with examples from various fields. ABSTRACT Diagnostic tests are central to medical care, and their evaluation remains methodologically challenging ...
Nancy Vegas   +2 more
wiley   +1 more source

Accuracy of surrogate outcomes in predicting true endpoints of surgical periodontal therapy. A narrative review with a 20‐year longitudinal analysis

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Periodontal clinical trials commonly use surrogate end points (e.g., probing pocket depth [PPD], clinical attachment level [CAL], bleeding on probing [BoP], and composite scores such as the Periodontal Risk Score [PRS]) for efficiency, yet tooth loss, treatment burden/cost, and re‐treatment are the definitive patient‐relevant ...
Muhammad H. A. Saleh   +7 more
wiley   +1 more source

RETRACTED: Polygenic risk score and prostate specific antigen predict death from prostate cancer in men with intermediate aggressive cancer

open access: yesInternational Journal of Cancer, Volume 159, Issue 5, Page E1-E13, 1 September 2026.
What's New? Using 21 SNPs, two novel PRS were constructed and used to develop two new machine‐learning classifiers, one for the detection of prostate cancer and the other for the prediction of its aggressiveness and subsequent mortality. The classifier for disease detection is built using the PRS as the sole feature, whereas the one for disease ...
Leandro Rodrigues Santiago   +3 more
wiley   +1 more source

Preoperative Prognostic Nutritional Index Predicts Prolonged Postoperative Hospital Stay in Patients With Oral Cancer Undergoing Highly Invasive Surgery

open access: yesOral Science International, Volume 23, Issue 3, September 2026.
ABSTRACT Aim To evaluate whether preoperative prognostic nutritional index (PNI) values predict prolonged postoperative hospital stay in patients with oral cancer undergoing highly invasive surgery. Methods We retrospectively evaluated background factors (age, sex, primary site, preoperative clinical stage, type of free flap, and the PNI) and ...
Go Ohara   +6 more
wiley   +1 more source

Early Risk Identification of Sepsis During Induction Chemotherapy in Newly Diagnosed AML: A Nomogram‐Based Tool

open access: yesCancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Background Patients with acute myeloid leukemia (AML) experience severe infections frequently during and after chemotherapy. The purpose of this study was to develop an early risk assessment tool to identify newly diagnosed AML patients at high risk of developing sepsis during the early phase of induction chemotherapy.
Cui‐Ying Gu   +4 more
wiley   +1 more source

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