Diagnostic Accuracy Studies: Sensitivity, Specificity, and Beyond
This methodological article covers key diagnostic accuracy measures, common pitfalls in diagnostic accuracy studies, and how evidence should progress from diagnostic accuracy to clinical effectiveness, with examples from various fields. ABSTRACT Diagnostic tests are central to medical care, and their evaluation remains methodologically challenging ...
Nancy Vegas +2 more
wiley +1 more source
Evaluation of the Safety and Effectiveness of Two Nomograms for the Management of Diabetic Ketoacidosis. [PDF]
Dhak M, Ammar A, Giuliano C.
europepmc +1 more source
Prescription of aminoglycosides by nomogram [PDF]
openaire +2 more sources
Abstract Background Periodontal clinical trials commonly use surrogate end points (e.g., probing pocket depth [PPD], clinical attachment level [CAL], bleeding on probing [BoP], and composite scores such as the Periodontal Risk Score [PRS]) for efficiency, yet tooth loss, treatment burden/cost, and re‐treatment are the definitive patient‐relevant ...
Muhammad H. A. Saleh +7 more
wiley +1 more source
Reply to Asim Armagan Aydin, Erkan Kayikcioglu, and Ramazan Oguz Yuceer's Letter to the Editor re: Muhammet Demirbilek, Göktuğ Kalender, Said Bıyıkoglu, et al. External Validation of Nomograms for Predicting Pelvic Lymph Node Metastases in Patients with Prostate Cancer and the Added Value of the Prostate-specific Membrane Antigen Positron Emission Tomography-based PRIMARY Score. Eur Urol Open Sci 2025;82:170-7. [PDF]
Önal B, Demirbilek M, Kabasakal L.
europepmc +1 more source
The isolated working guinea pig heart: A functional and electrophysiological characterisation
Abstract Small animal isolated perfused hearts have been used for over 150 years for the study of cardiac physiology and pharmacology. The guinea pig heart represents the smallest mammalian heart that replicates key features of the human heart – for example, with respect to cardiac action potential duration, ion channel expression, excitation ...
Grace C. Anderson‐Barker +1 more
wiley +1 more source
Prognostic Nomograms and Scoring System: Novel Approaches to Forecast Overall Survival and Cancer-Specific Survival in Patients With Testicular Cancer. [PDF]
Huang X +5 more
europepmc +1 more source
ABSTRACT Aim To evaluate whether preoperative prognostic nutritional index (PNI) values predict prolonged postoperative hospital stay in patients with oral cancer undergoing highly invasive surgery. Methods We retrospectively evaluated background factors (age, sex, primary site, preoperative clinical stage, type of free flap, and the PNI) and ...
Go Ohara +6 more
wiley +1 more source

