Results 181 to 190 of about 33,934 (312)

Diagnostic Accuracy Studies: Sensitivity, Specificity, and Beyond

open access: yesJournal of Periodontal Research, EarlyView.
This methodological article covers key diagnostic accuracy measures, common pitfalls in diagnostic accuracy studies, and how evidence should progress from diagnostic accuracy to clinical effectiveness, with examples from various fields. ABSTRACT Diagnostic tests are central to medical care, and their evaluation remains methodologically challenging ...
Nancy Vegas   +2 more
wiley   +1 more source

Accuracy of surrogate outcomes in predicting true endpoints of surgical periodontal therapy. A narrative review with a 20‐year longitudinal analysis

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Periodontal clinical trials commonly use surrogate end points (e.g., probing pocket depth [PPD], clinical attachment level [CAL], bleeding on probing [BoP], and composite scores such as the Periodontal Risk Score [PRS]) for efficiency, yet tooth loss, treatment burden/cost, and re‐treatment are the definitive patient‐relevant ...
Muhammad H. A. Saleh   +7 more
wiley   +1 more source

The isolated working guinea pig heart: A functional and electrophysiological characterisation

open access: yesExperimental Physiology, EarlyView.
Abstract Small animal isolated perfused hearts have been used for over 150 years for the study of cardiac physiology and pharmacology. The guinea pig heart represents the smallest mammalian heart that replicates key features of the human heart – for example, with respect to cardiac action potential duration, ion channel expression, excitation ...
Grace C. Anderson‐Barker   +1 more
wiley   +1 more source

Preoperative Prognostic Nutritional Index Predicts Prolonged Postoperative Hospital Stay in Patients With Oral Cancer Undergoing Highly Invasive Surgery

open access: yesOral Science International, Volume 23, Issue 3, September 2026.
ABSTRACT Aim To evaluate whether preoperative prognostic nutritional index (PNI) values predict prolonged postoperative hospital stay in patients with oral cancer undergoing highly invasive surgery. Methods We retrospectively evaluated background factors (age, sex, primary site, preoperative clinical stage, type of free flap, and the PNI) and ...
Go Ohara   +6 more
wiley   +1 more source

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