Results 161 to 170 of about 33,934 (312)

T Cell Heterogeneity Shaped by Alternative Splicing Predicts Prognosis in Hepatocellular Carcinoma

Cancer Science, EarlyView.
T cell‐specific alternative splicing events shape T cell heterogeneity in HCC. Single‐cell analysis identified two splicing‐defined T cell subpopulations with distinct functional profiles. Subpopulation‐associated splicing events were used to construct a prognostic model predicting patient survival.
Xiaohui Peng, Zhenli Li, Xiuqing Dong, Zhixiong Cai, Chenfan Lu, Junjie Gao, Shuyue You, Yuwen Wang, Jianming Mao, Xiaolong Liu, Geng Chen, Yingchao Wang   +11 more
wiley   +1 more source

Epithelial YPEL3 Modulates CD8+ T‐Cell Infiltration and Tumor Progression Through CREB1–CXCL16 Signaling in HNSCC

Cancer Science, EarlyView.
YPEL3 functions as a tumor suppressor in HNSCC by inhibiting tumor progression and promoting apoptosis. Mechanistically, it enhances epithelial–immune crosstalk through the CREB1‐mediated CXCL16–CXCR6 axis, facilitating CD8+ T‐cell infiltration and highlighting its potential as a prognostic biomarker and immunotherapy target.
Yalun Li, Yumei Li, Caiyu Sun, Congxian Lu, Gang Chen, Tianshu Zhou, Bei Zhang, Xicheng Song   +7 more
wiley   +1 more source

Femtosecond Laser Created Corneal Allogenic Intrastromal Ring Segments for Keratoconus

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background To evaluate the clinical outcomes of femtosecond laser‐created corneal allogenic intrastromal ring segments (femto‐CAIRS) in keratoconic eyes using a newly described nomogram. Methods This retrospective case series recruited 85 eyes from 75 patients.
David J. Gunn, Rebecca A. Cox, Brendan Cronin   +2 more
wiley   +1 more source

New Standardized PSMA PET Reporting Framework for Long-Term Survival Prediction in Prostate Cancer. [PDF]

Radiol Imaging Cancer
Ali FZ.
europepmc   +1 more source

Nomogram for Anaesthetic Uptake [PDF]

Anaesthesia and Intensive Care, 1994
H J, Lowe, J F, Viljoen
openaire   +2 more sources

Comparative predictive accuracy of machine learning versus traditional statistical methods for diabetes‐related complications: A systematic review and analysis

Diabetic Medicine, EarlyView.
This systematic review of 36 studies comparing machine learning with traditional statistical models for predicting diabetes‐related complications found modest discrimination gains with ensemble approaches, particularly random forest and gradient boosting.
Bismah Ghafoor, Francesco Zaccardi, Kamlesh Khunti, Sharmin Shabnam   +3 more
wiley   +1 more source

Utilising VISULYZE-Generated Nomograms and OcuLign Alignment Tools to Improve Keratorefractive Lenticule Extraction Outcomes. [PDF]

J Clin Med
Siregar SR, Ardiani LS, Hutauruk JA.
europepmc   +1 more source

To Treat or Not to Treat: Navigating Early‐Stage CLL in the Era of Targeted Therapy

European Journal of Haematology, EarlyView.
ABSTRACT Chronic lymphocytic leukemia (CLL) is most frequently diagnosed at early, asymptomatic stages (Rai 0/Binet A), in which a watch‐and‐wait strategy remains the standard of care, based on historical trials demonstrating no overall survival benefit from early treatment.
Enrica Antonia Martino, Santino Caserta, Ernesto Vigna, Giovanna Cutrona, Antonella Bruzzese, Francesco Mendicino, Maria Eugenia Alvaro, Caterina Labanca, Eugenio Lucia, Virginia Olivito, Nicola Amodio, Franco Fais, Antonino Neri, Manlio Ferrarini, Valter Gattei, Fortunato Morabito, Massimo Gentile   +16 more
wiley   +1 more source

Clinico-genomic nomograms for estimation of survival risk in metastatic castrate-resistant prostate cancer. [PDF]

JNCI Cancer Spectr
Kohli M, Shankar A, Lloyd J, Wang L, Huo X, Fadlullah MZ, Tan AC, Finkelstein J.   +7 more
europepmc   +1 more source

Coronal and Root Caries in Older Adults: Associated Factors, Quality of Life Impact, and Treatment—A Scoping Review

Gerodontology, EarlyView.
ABSTRACT Background Dental caries remains one of the most common chronic diseases affecting older adults worldwide. As edentulism decreases and more natural teeth are retained into old age, the number of susceptible tooth surfaces increases. Age‐related factors such as polypharmacy, cognitive decline, and reduced oral hygiene skills, together with ...
Helena Dujic, Katrin Heck, Julia Schwärzler, Cristiane da Mata, Sayaka Tada, Falk Schwendicke   +5 more
wiley   +1 more source