Results 141 to 150 of about 524,132 (248)

Does perceived stigma impact opioid use disorder treatment uptake? A cross-sectional secondary analysis of buprenorphine engagement among syringe service program participants. [PDF]

Addict Sci Clin Pract
Campbell B, Riback LR, Portillo JG, Maricic S, Fox AD.   +4 more
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Substance Use, Sexual Activity Prevalence, and Knowledge Gaps in Young Adults with Type 1 Diabetes in a Pediatric Clinic. [PDF]

Diabetes Metab Syndr Obes
Waterman LA, Polsky S, Akturk HK, Stewart B, Karami AJ, Taylor K, Cobry EC.   +6 more
europepmc   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Risk reduction behaviours following the detection of unexpected drugs through community drug checking: a cross-sectional study. [PDF]

Harm Reduct J
Tobias S, Grant C, Lysyshyn M, Roux P, Wood E, Kerr T, Ti L.   +6 more
europepmc   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Mindfulness-Based Interventions for Adolescent Substance Use and Substance Use Disorders: A Systematic Review. [PDF]

Pediatrics
Hammond CJ, Webb L, Lee CY, Adegbindin A, Park G, Lebo R, Nanavati J, Sibinga E.   +7 more
europepmc   +1 more source

Hillsborough County Board of Education and Hillsborough School Employees Federation, Florida Education Association, National Education Association (NEA), (2002) [PDF]

, 2002

core   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Protocol for a randomized controlled trial to evaluate the efficacy of inhibitory control training for aggressive behaviours among individuals with co-occurring substance use disorder and gambling behaviour. [PDF]

Trials
Ahluwalia Y, Sarkar S, Kaloiya GS, Deo V, Singh S, Gupta SK, Balhara YPS.   +6 more
europepmc   +1 more source