Results 1 to 10 of about 60,239 (217)

Democratizing cheminformatics: interpretable chemical grouping using an automated KNIME workflow

Journal of Cheminformatics
With the increased availability of chemical data in public databases, innovative techniques and algorithms have emerged for the analysis, exploration, visualization, and extraction of information from these data.
José T. Moreira-Filho, Dhruv Ranganath, Mike Conway, Charles Schmitt, Nicole Kleinstreuer, Kamel Mansouri   +5 more
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Toxicological evaluation of the effect of phenol-contaminated water on the liver of albino rats

CHRISMED Journal of Health and Research, 2015
Phenol is a constituent of coal tar and is formed during the natural decomposition of organic materials. The effect of phenol-contaminated water on the liver of rats was investigated.
Aanuoluwa James Salemcity, Titilope Ayoola Iyanda, Olakunle Oladimeji, Ayobami Matthew Olajuyin   +3 more
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Assessing potential desflurane-induced neurotoxicity using nonhuman primate neural stem cell models

Experimental Biology and Medicine
Safety concerns about general anesthetics (GA), such as desflurane (a commonly used gaseous anesthetic agent), arose from studies documenting neural cell death and behavioral changes after early-life exposure to anesthetics and compounds with related ...
Cheng Wang, Leah E. Latham, Shuliang Liu, John Talpos, Tucker A. Patterson, Joseph P. Hanig, Fang Liu   +6 more
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Scientific support for preparing an EU position in the 55th Session of the Codex Committee on Pesticide Residues (CCPR)

EFSA Journal
The European Commission asked EFSA to provide support in the framework of Article 43 of Regulation (EC) No 396/2005 for the preparation of the EU position for 55th Session of the Codex Committee on Pesticide Residues (CCPR).
EFSA (European Food Safety Authority)
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Nutritional Potential and Toxicological Evaluation of Tetraselmis sp. CTP4 Microalgal Biomass Produced in Industrial Photobioreactors

Molecules, 2019
Commercial production of microalgal biomass for food and feed is a recent worldwide trend. Although it is common to publish nutritional data for microalgae grown at the lab-scale, data about industrial strains cultivated in an industrial setting are ...
Hugo Pereira, Joana Silva, Tamára Santos, Katkam N. Gangadhar, Ana Raposo, Cláudia Nunes, Manuel A. Coimbra, Luísa Gouveia, Luísa Barreira, João Varela   +9 more
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Extractables and Leachables in Pharmaceutical Products: Potential Adverse Effects and Toxicological Risk Assessment

Toxics
During production, storage, and administration, drug products (and their intermediates) are in contact with many different types of materials, which include manufacturing components, container closure systems, and administration materials; therefore ...
Samo Kuzmič, Tjaša Zlobec, Marija Sollner Dolenc, Robert Roškar, Tina Trdan Lušin   +4 more
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Scientific support for preparing an EU position in the 47th Session of the Codex Committee on Pesticide Residues (CCPR)

EFSA Journal, 2015
In accordance with Article 43 of Regulation (EC) 396/2005, EFSA received a request from the European Commission to provide support for the preparation of the EU position for 47th session of the Codex Committee on Pesticide Residues (CCPR).
European Food Safety Authority
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Tissue-specific mutagenicity of N-nitroso-methylphenylamine assayed by the transgenic rodent assay and duplex sequencing

Frontiers in Toxicology
N-Nitroso-methylphenylamine (NMPA) is a rat esophageal carcinogen that has been found in food, tobacco and drugs. In this study, NMPA was administered via drinking water to Big Blue transgenic rats over 28 days following methods recommended in OECD TG ...
Li Xia, Jian Yan, Kamela Mitchell, Robert H. Heflich, Ying Chen, Timothy J. McGovern, Aisar H. Atrakchi, Tao Chen   +7 more
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The effect of black cohosh extract and risedronate coadministration on bone health in an ovariectomized rat model

Frontiers in Pharmacology
Preparations of black cohosh extract are sold as dietary supplements marketed to relieve the vasomotor symptoms of menopause, and some studies suggest it may protect against postmenopausal bone loss.
Amy L. Inselman, Elysia A. Masters, Jalina N. Moore, Rajiv Agarwal, Audrey Gassman, Gemma Kuijpers, Richard D. Beger, Kenneth B. Delclos, Sybil Swift, Luísa Camacho, Michelle M. Vanlandingham, Daniel Sloper, Noriko Nakamura, Gonçalo Gamboa da Costa, Kellie Woodling, Matthew Bryant, Raul Trbojevich, Qiangen Wu, Florence McLellen, Donna Christner   +19 more
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Screening of foods additives on infusoria

RUDN Journal of Ecology and Life Safety, 2011
In the paper shows possibility of using the bioassay of food additives on the ciliates. The experiment was performed on an automated instrument BioLaT.
Е G Cheremnykh, А V Kuleshin, O N Kuleshina   +2 more
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